Kosakonia cowanii: BWI95_21170
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Entry
BWI95_21170 CDS
T04691
Name
(GenBank) bifunctional tetrahydrofolate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
kco
Kosakonia cowanii
Pathway
kco00790
Folate biosynthesis
kco01100
Metabolic pathways
kco01240
Biosynthesis of cofactors
Module
kco_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
kco00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
BWI95_21170
Enzymes [BR:
kco01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
BWI95_21170
6.3.2.17 tetrahydrofolate synthase
BWI95_21170
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
APZ07378
UniProt:
A0A830ZEB1
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Position
complement(4470164..4471432)
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AA seq
422 aa
AA seq
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MDTLSTPQATSPLAAWLSYLEQLHSKPIDLGLDRVSQVAARLDVLRPAPFVFTVAGTNGK
GTTCRTLESILLAAGYRVGVYSSPHLVRYTERVRVQGGELAESAHTASFAEIEAVRGDIS
LSYFEFSTLSALWLFKQAQLDVVILEVGLGGRLDATNMVDADVAVVTSIALDHTDWLGPD
RESIGREKAGIFRAGKPAVVGEPDMPHTIADVAQEKGAQLLQRDVAWHYEVGAQSWRFRD
AQGELSDLPLPQVPQPNAATALAALRASKLAVSEQAICDGIERAILPGRFQIVSESPRLI
LDVAHNPHAAGYLAGRLAALPKSGRVLAVVGMLHDKDISGTLACLEPVVDSWYCAPLEGP
RGATAEQLLAHLTSGQAFPDVTQAWQAAMAEADACDTVLVCGSFHTVAHVMEAMEAGRTG
GK
NT seq
1269 nt
NT seq
+upstream
nt +downstream
nt
atggacactctctctactccgcaagccacgtcgcccctggccgcatggctctcttatctg
gaacagctgcacagtaaacctatcgatttagggctcgatcgcgtaagccaggtggcggcg
cggcttgatgtgctgcgtcccgcaccttttgtcttcaccgtcgccggaaccaacggcaaa
ggcaccacctgccgtacgctggagtcgatcctgctggcggccggttatcgcgttggtgtt
tatagctcgccgcatctggtgcgctacaccgaacgcgtgcgcgtacagggcggggagctg
gcagaaagcgcgcataccgcttccttcgcggagatcgaagccgtgcgcggcgatatctct
ttaagctattttgaatttagcaccctgtcagcgctgtggctgtttaagcaggcgcaactg
gacgtggtgatcctcgaagtgggcctcggtggacgtctcgacgccaccaatatggtcgat
gccgatgtcgcggtggtcaccagcattgcgctcgatcataccgactggctcgggccggat
cgcgaaagcatcggccgtgaaaaagcgggcatcttccgtgccggtaaacccgcggtggtt
ggcgagccggatatgccgcacaccatcgctgatgtggcgcaggagaaaggcgcgcagctg
ttacagcgcgatgtggcgtggcactacgaggttggcgcgcagagctggcgttttcgcgat
gcgcagggtgagctgagcgatctgccgctgccgcaggtgccgcagccgaacgcggctacc
gcgctggccgcgctgcgcgccagtaaactggcagtaagcgagcaggcgatctgcgacggc
atagaacgggcgattttacccggtcgttttcagattgtgagcgaatcaccacgtctgatc
cttgatgtcgcgcataatcctcatgccgcaggctatcttgccgggcggctggcggcgctg
ccaaaaagcggccgcgtgctggcggtggttggcatgctgcatgataaagacattagcgga
acgcttgcctgtctggagccggtggtcgatagctggtattgtgcccctctggaggggccg
cgcggcgcgacggcggagcagctgctggcgcacctgacgtcggggcaagcattcccggac
gtgacccaggcctggcaggcggcaatggcggaggccgacgcctgcgataccgtgctggtg
tgtggctcgttccacaccgtggcgcatgtcatggaagcgatggaagcggggagaaccggt
ggcaagtaa
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