KEGG T05915: DA718

Klebsiella huaxiensis: DA718_08250

Entry

DA718_08250       CDS       T05915

Symbol

folC

Name

(GenBank) bifunctional tetrahydrofolate synthase/dihydrofolate synthase

K11754

dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17]

Organism

klw Klebsiella huaxiensis

Pathway

klw00790

Folate biosynthesis

klw01100

Metabolic pathways

klw01240

Biosynthesis of cofactors

Module

klw_M00126

Tetrahydrofolate biosynthesis, GTP => THF

Brite

KEGG Orthology (KO) [BR:klw00001]
09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    DA718_08250 (folC)
Enzymes [BR:klw01000]
6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.12  dihydrofolate synthase
     DA718_08250 (folC)
    6.3.2.17  tetrahydrofolate synthase
     DA718_08250 (folC)

SSDB

Motif

Pfam:

Mur_ligase_M Mur_ligase_C

Other DBs

NCBI-ProteinID:

QBG07179

LinkDB

Position

1710360..1711628

AA seq 422 aa
MEKQPIPQAASPLATWLSYLEHLHSKTIDLGLARVSEVAVRMAVLKPAPFVFTVAGTNGK
GTTCRTLESVLMAAGFKVGVYSSPHLVRYTERVRVQGEELSELAHTTSFAEIEAARGEIS
LSYFEFGTLSALWLFQQAQLDVVILEVGLGGRLDATNIVDADVAVVTSIALDHTDWLGPD
RESIGREKAGIFRGGKPAIVGEPDMPQTIAEVASEKGAQLLRRDVDWGYEAGEQSWSFSD
ENGALTDLPLPQVPMPNAATALAALRASKLKVDEQAIRDGIQKAMLPGRFQIISDTPRVI
LDVAHNPHAATYLAGRLKTLPKTGRVLAVIGMLHDKDIAGTLENLKAEVDDWYCAPLEGP
RGATAEQLLEHLRAGKVYTSVVQAWYAAMADARPQDTVLVCGSFHTVAHVMEEIDAGRIG
GE

NT seq 1269 nt +upstreamnt +downstreamnt
atggaaaaacaacctattcctcaggccgcgtcgcccctggctacgtggctttcttatctg
gaacatctgcacagcaaaacaatcgacctgggactggcgcgcgtcagcgaggtggctgtg
cggatggcggtattaaaacctgcgccgtttgtgttcacggtggcgggaaccaacggcaaa
ggaacgacctgccgtaccctggaatcggtactgatggccgcgggcttcaaagtgggtgtt
tatagttcgccgcatctggtgcgctataccgagcgggtgcgcgtacaaggcgaagagctg
tcggaacttgcgcataccacttcctttgctgaaatcgaagcggcgcgtggcgagatttct
ctgagctattttgaatttggtacgctttccgcgctgtggctatttcagcaggcgcaactg
gatgtcgttatccttgaagtgggtctcggcggtcgcctggatgcgactaatattgttgat
gccgacgtggcggtagtcaccagtattgcgcttgaccatacggactggctgggaccggat
cgcgaaagcattggccgcgagaaggcaggtatttttcgcggtggtaaaccggctatcgtt
ggtgaacccgatatgccccagactatcgccgaggttgcgagcgaaaagggcgcgcaactc
ctgcgccgcgacgttgactggggctatgaggccggtgagcagagctggtctttcagtgat
gaaaacggcgcactcaccgacctgccgctgccacaggtacctatgccgaatgccgcaact
gcgctcgctgccctgcgtgccagcaagctcaaggttgacgagcaggcgattcgcgacggt
attcaaaaggcgatgctgccggggcgttttcagataattagcgacaccccgagagtcatc
cttgatgttgctcataacccgcatgcggcgacgtatctcgccgggcgtctcaaaacctta
ccgaaaacggggcgcgtgctggcggttattggtatgctgcatgataaggacatcgccggt
acgctggaaaacctgaaggcggaagttgacgattggtactgtgcgccgctggaagggccg
cgcggcgcgacggcagagcaactgctggaacatttacgcgcaggcaaagtctataccagc
gttgtgcaggcctggtacgctgcgatggcagatgccagaccacaggatacggtgctggtg
tgtggttcattccacacggtggcgcatgtaatggaagagatagacgcggggagaatcggt
ggcgagtaa

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