Klebsiella michiganensis HKOPL1: J415_02430
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Entry
J415_02430 CDS
T03188
Symbol
metL
Name
(GenBank) bifunctional aspartate kinase II/homoserine dehydrogenase II
KO
K12525
bifunctional aspartokinase / homoserine dehydrogenase 2 [EC:
2.7.2.4
1.1.1.3
]
Organism
koy
Klebsiella michiganensis HKOPL1
Pathway
koy00260
Glycine, serine and threonine metabolism
koy00261
Monobactam biosynthesis
koy00270
Cysteine and methionine metabolism
koy00300
Lysine biosynthesis
koy01100
Metabolic pathways
koy01110
Biosynthesis of secondary metabolites
koy01120
Microbial metabolism in diverse environments
koy01230
Biosynthesis of amino acids
Module
koy_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
koy_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
koy00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
J415_02430 (metL)
00270 Cysteine and methionine metabolism
J415_02430 (metL)
00300 Lysine biosynthesis
J415_02430 (metL)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
J415_02430 (metL)
Enzymes [BR:
koy01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
J415_02430 (metL)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
J415_02430 (metL)
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Motif
Pfam:
Homoserine_dh
AA_kinase
NAD_binding_3
Motif
Other DBs
NCBI-ProteinID:
AHW86052
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Position
complement(544510..546942)
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AA seq
810 aa
AA seq
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MSVIAQAGAKGRQLHKFGGSSLADAKCYLRVAGIMTEYSQAGDMMVVSAAGSTTNQLISW
LKLSQTDRLSAHQVQQSLRRYQMELISGLLSPDAADTLIAIFIQDLERLAGLLDGGVTDA
VYAEVVGHGEVWSARLMAAVLNHLGVEAAWLDARSFLRAERSAQPQVDEGLSYPLLQQLI
AQHPNKRLVVTGFISRNNAGETVLLGRNGSDYSATQIGALAGASRVTIWSDVAGVYSADP
RKVKDACLLPLLRLDEASELARLAAPVLHARTLQPVSGSDIDLQLRCSYTPDQGSTRIER
VLASGTGARIVTSHDDVCLIEFQVPGGQDFKLAHKELDAILKRAQLRPLAVGVHADRKLL
QFCYTSEVADSALKLLDEAGLPGELRLRQKLALVAMVGAGVTRNPLHCHRFWQQLKGQPV
EFTWQSEEGISLVAVLRAGPTESLIQGLHQSLFRAEKRIGLVLFGKGNIGSRWLELFARE
QTTLSARTGFEFILAGVVDSRRSLLNYEGLDASRALAFFNDEAVEQDEESLFLWMRAHPY
DDLVVLDVTASAQLADQYLDFASHGFHVISANKLAGASSSSKYRQIHDAFEKTGRHWLYN
ATVGAGLPVNHTVRDLIDSGDTILALSGIFSGTLSWLFLQFDGTVPFTDLVDQAWQQGLT
EPDPRVDLSGKDVMRKLVILAREAGYNIEPDQVRVESLVPAHCEEGSVDHFFENGEALNE
QMLQRLEAAREMGLVLRYVARFDANGKARVGVEAVREEHPLAALLPCDNVFAIESRWYRD
NPLVIRGPGAGRDVTAGAIQSDINRLAQLL
NT seq
2433 nt
NT seq
+upstream
nt +downstream
nt
atgagtgtgattgcgcaggcaggggcgaagggtcgtcagctgcacaaatttggtgggagt
agtttagcggatgcgaaatgttacctgcgcgtcgcgggtattatgacggagtattcgcag
gcgggcgacatgatggtcgtctctgccgccggcagtaccaccaaccagttgatcagctgg
ctgaagctcagccagaccgatcgcctttctgcgcatcaggtgcaacaatcgctccgtcgt
tatcagatggagctcatctccggactgctgtcaccagacgctgccgacacgctgattgcc
atctttattcaggatcttgagcgccttgccgggttgcttgacggcggcgtcaccgacgcg
gtatacgccgaagtcgtcggtcacggcgaagtctggtcggcccgcctgatggcggcggtg
ctgaaccatcttggcgtagaagccgcctggctggatgcgcgtagcttcctgcgcgccgag
cgctccgcgcagccgcaggtggatgaaggtttatcctatccgcttttgcagcagctgata
gcgcagcacccgaacaagcgtctggtggtgaccggctttatttcgcgtaacaacgccggg
gaaaccgtcctgctggggcgtaacggttccgactattccgccacccaaatcggcgccctg
gccggggcgtctcgcgtcactatctggagcgacgtggccggggtctacagcgcggatccg
cgtaaagtgaaagacgcctgcctgctgccgctgctgcgcctggatgaggccagcgaactg
gcccgcctggcggcgccggtgctgcatgcccgtacgctgcagccggtctccggcagcgat
atcgatttacaattacgctgtagctacaccccggatcagggctcaacgcgcatcgaacgc
gtgctggcttccggtaccggggcgcgtatcgtgaccagccatgatgatgtctgcctgatt
gagttccaggtacccggcggccaggatttcaaactggcgcataaagagctggacgctatc
ttaaaacgcgcccagctgcgtccgctggcggttggcgtacacgccgaccgtaagctgctg
cagttctgctacacctctgaagtggccgacagcgcgctgaagctgctggacgaagcgggg
ctgccgggcgagctgcgcctgcgtcagaaactggcgctggtggcgatggttggcgctggc
gtgacccgcaatccgctgcactgccaccgtttctggcagcagctgaagggtcagccggta
gagtttacctggcaatcagaagagggcatcagcctggtcgcggtgctgcgcgccgggccg
acggaaagtcttattcaggggctgcatcagtcgttgttccgcgcggaaaaacgcattggc
ctggtgctgtttggcaaaggtaatatcgggtcccgctggctggagctgttcgctcgcgag
cagaccacgctttccgcccgcaccgggtttgaattcatccttgccggggtcgtggatagt
cgccgtagcctgcttaattacgaaggccttgacgccagtcgcgcgctggctttctttaat
gatgaggccgttgagcaggatgaagagtcgctgttcctgtggatgcgcgcgcatccgtac
gatgatttagtggtgctggacgtaaccgccagcgcgcagctggccgaccagtacctcgat
ttcgccagccatggtttccacgttatcagcgcgaataagctggctggcgccagcagcagc
agtaagtatcgccagatccacgacgcgttcgagaagaccgggcgccactggctgtacaac
gccaccgtcggcgccggtttaccggtcaaccatacggtgcgcgatttgattgatagcggc
gataccattctggcgctgagcggtattttctccggcaccctctcatggctgttcctgcag
tttgacggcaccgtgccgtttacagacctcgtcgatcaggcctggcagcaggggctgacg
gaaccggacccgcgcgtcgatctctccgggaaagacgttatgcgtaagctggtgatcctg
gcccgtgaggcgggttacaacatcgagccggatcaggtgcgcgttgagtcgctggtgccc
gcccactgcgaagaggggtctgtcgatcacttctttgagaacggcgaagcgctgaacgag
cagatgctgcagcgtctggaagcggcgcgcgagatgggcctggtgctgcgctacgtcgcg
cgctttgatgctaacggtaaagcccgcgtcggcgtggaagcggtgcgcgaagagcacccg
ctggcggcgctgctgccgtgtgataacgtctttgctatcgagagccgctggtatcgcgat
aacccgctggtgatccgcggtccgggcgccggtcgcgatgtgaccgccggggcgattcag
tcggatatcaaccgtctggcgcagctgctgtag
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