Klebsiella pneumoniae blaNDM-1: FH42_21440
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Entry
FH42_21440 CDS
T03440
Name
(GenBank) bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase
KO
K01682
aconitate hydratase 2 / 2-methylisocitrate dehydratase [EC:
4.2.1.3
4.2.1.99
]
Organism
kpb
Klebsiella pneumoniae blaNDM-1
Pathway
kpb00020
Citrate cycle (TCA cycle)
kpb00630
Glyoxylate and dicarboxylate metabolism
kpb00640
Propanoate metabolism
kpb01100
Metabolic pathways
kpb01110
Biosynthesis of secondary metabolites
kpb01120
Microbial metabolism in diverse environments
kpb01200
Carbon metabolism
kpb01210
2-Oxocarboxylic acid metabolism
kpb01230
Biosynthesis of amino acids
Module
kpb_M00009
Citrate cycle (TCA cycle, Krebs cycle)
kpb_M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
kpb_M00012
Glyoxylate cycle
Brite
KEGG Orthology (KO) [BR:
kpb00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
FH42_21440
00630 Glyoxylate and dicarboxylate metabolism
FH42_21440
00640 Propanoate metabolism
FH42_21440
Enzymes [BR:
kpb01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.3 aconitate hydratase
FH42_21440
4.2.1.99 2-methylisocitrate dehydratase
FH42_21440
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SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Aconitase_2_N
Aconitase_B_N
Aconitase
AcnX
Motif
Other DBs
NCBI-ProteinID:
AIJ43197
UniProt:
W9BCI4
LinkDB
All DBs
Position
4436795..4439419
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AA seq
874 aa
AA seq
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MTMRARRTVVLEEYRKHVAERAAMGIVAKPLDATQMAALVELLKNPPAGEEEFLLDLLIN
RVPPGVDEAAYVKAGFLAAIAKGEATSPLVTPEKAVELLGTMQGGYNIHPLIDALDDAKL
APIAAKALSHTLLMFDNFYDVEEKAKAGNEHAKQVMQSWADAEWFLNRPQLAEKITVTVF
KVTGETNTDDLSPAPDAWSRPDIPLHALAMLKNPREGIEPDQPGVVGPIKQIEALQQKGY
PLAYVGDVVGTGSSRKSATNSVLWFMGDDIPNVPNKRGGGLCLGGKIAPIFFNTMEDAGA
LPIEVDVSNLNMGDVIDVYPFKGEVRNHETNELLASFELKTDVLIDEVRAGGRIPLIIGR
GLTTKAREALGLPHSDVFRQAKDVAESTRGFSLAQKMVGRACGVAGIRPGAYCEPKMTSV
GSQDTTGPMTRDELKDLACLGFSADLVMQSFCHTAAYPKPVDVTTHHTLPDFIMNRGGVS
LRPGDGVIHSWLNRMLLPDTVGTGGDSHTRFPIGISFPAGSGLVAFAAATGVMPLDMPES
VLVRFKGKMQPGITLRDLVHAIPLYAIKQGLLTVEKKGKKNIFSGRILEIEGLPDLKVEQ
AFELTDASAERSAAGCTIKLNKEPIVEYLNSNIVLLKWMIAEGYGDRRTLERRIQGMEKW
LADPQLLEADADAEYAAVIDIDLADIKEPILCAPNDPDDARLLSDVQGEKIDEVFIGSCM
TNIGHFRAAGKLLDSHKGQLPTRLWVAPPTRMDAAQLTEEGYYSVFGKSGARIEIPGCSL
CMGNQARVADGATVVSTSTRNFPNRLGTGANVYLASAELAAVASLLGKLPTPEEYQTFVA
QVDKTAEDTYRYLNFNQLDQYTEKADGVIFQTAV
NT seq
2625 nt
NT seq
+upstream
nt +downstream
nt
atgacaatgagagcgaggagaaccgtcgtgctagaagaataccgtaagcacgtagctgag
cgtgccgccatggggattgttgccaaacccttagatgcaacccaaatggccgcgctggta
gaactgctgaaaaacccgcctgcgggcgaagaagaattcctgttagacctgctgattaac
cgtgtaccgccgggcgtcgacgaagccgcctatgttaaagctggattccttgccgcgatc
gccaaaggcgaagcgacctcccccctggttacccctgaaaaagccgttgaactgctgggc
accatgcagggcggttacaatatccatccgctgatcgatgcgctggacgacgcgaaactg
gcgccgattgccgcgaaagcgctctcccataccctgctgatgttcgataacttctacgac
gtggaagagaaagccaaagcgggtaacgagcatgctaaacaggttatgcaatcctgggct
gacgccgagtggttcctgaaccgtccgcagctggcagagaaaatcactgttaccgtcttc
aaggtcaccggcgaaacgaacaccgatgatctctctccggcgccggatgcgtggtcgcgc
ccggatatcccgctgcatgcgctggcaatgctcaaaaacccccgcgaaggtattgagccg
gatcagccgggcgtggttggcccaatcaaacagatcgaagccctgcagcagaaaggctac
ccgctggcctacgtcggcgacgtggtcgggaccggttcttcacgtaaatccgccaccaac
tcggtgctgtggtttatgggcgacgatatcccgaacgtgccgaacaagcgcggcggcggc
ctgtgtctgggcggtaaaatcgcgccaattttcttcaacaccatggaagatgcgggcgcg
ctgcctatcgaagttgatgtgtctaacctgaacatgggcgacgtaatcgacgtttacccg
ttcaaaggcgaagtgcgtaaccacgagaccaacgaactgctggccagcttcgagctgaaa
accgatgtgctgatcgacgaagtgcgcgccggcggccgtattccgctgatcatcggtcgc
ggtctgaccaccaaagcgcgtgaagcgctgggcctgccgcacagcgatgtcttccgtcag
gcgaaagacgtggcggaaagcacccgcggcttctcgctggcgcagaaaatggttggccgc
gcctgcggcgttgccggtatccgtccgggcgcttattgcgaaccgaaaatgacctccgtc
ggttctcaggacaccaccggtccaatgacccgtgatgagctgaaagacctggcgtgcctg
ggcttctctgcagacctggtgatgcagtccttctgccacaccgcggcctacccgaagccg
gttgacgttaccacgcaccacactctgccggacttcatcatgaaccgcggcggtgtttct
ctgcgtccgggcgatggcgtgattcactcctggctgaaccgcatgctgctgccggatacc
gtgggtaccggcggtgactcccacacccgtttcccaatcggcatctccttcccggcaggc
tctggtctggtggccttcgccgccgcgaccggcgtgatgccgctggatatgccggaatcg
gtgctggtgcgtttcaaaggtaaaatgcagccggggatcaccctgcgtgacctggtccac
gccatcccgctgtacgccatcaagcagggcctgctgaccgtggagaagaaaggtaagaaa
aacatcttctctggtcgcatcctcgagatcgaaggtctgccggatctgaaagtcgagcag
gcgttcgagttgaccgatgcctcggcggagcgttctgccgccggctgcaccatcaagctg
aataaagagccgatcgttgagtatctgaactccaacatcgttctgctgaagtggatgatc
gccgaaggctacggcgaccgccgtaccctggagcgtcgtatccagggcatggaaaaatgg
ctggcggatccgcagctgctggaagccgatgctgacgcggaatacgcggcagtgatcgac
atcgatctggcggatattaaagagccgattctgtgcgcgccgaacgatccggacgatgcc
cgcctgctgtctgatgtgcagggcgagaagatcgacgaagtgttcatcggctcctgcatg
accaacatcggccacttccgtgccgccggtaagctgctggatagccacaaaggccaactg
ccgactcgcctgtgggtggcgccgccaacccgtatggatgccgcgcagctgaccgaagaa
ggctactatagcgtgtttggtaagagcggggcgcgtatcgaaatccctggctgttccctg
tgtatgggtaaccaggcgcgcgtggccgacggcgcgacggtggtttccacctctacccgt
aacttcccgaaccgtttaggtaccggcgctaacgtctatctggcctctgccgaactggca
gcggtggcttcgctgctcggcaaactgccgacgccggaagagtaccagaccttcgtggcg
caggtggataagacggcggaagatacctaccgttatctgaacttcaaccagctggatcag
tacactgaaaaagctgacggcgtgatcttccagaccgcggtgtaa
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