KEGG T06085: R2C4

Leisingera aquaemixtae: R2C4_19450

Entry

R2C4_19450        CDS       T06085

Name

(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase

K11754

dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17]

Organism

laqu Leisingera aquaemixtae

Pathway

laqu00790

Folate biosynthesis

laqu01100

Metabolic pathways

laqu01240

Biosynthesis of cofactors

Module

laqu_M00126

Tetrahydrofolate biosynthesis, GTP => THF

Brite

KEGG Orthology (KO) [BR:laqu00001]
09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    R2C4_19450
Enzymes [BR:laqu01000]
6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.12  dihydrofolate synthase
     R2C4_19450
    6.3.2.17  tetrahydrofolate synthase
     R2C4_19450

SSDB

Motif

Pfam:

Mur_ligase_M

Other DBs

NCBI-ProteinID:

QDI77822

LinkDB

Position

3629471..3630739

AA seq 422 aa
MTQTSDAILARMMALHPKIIDLTLDRVWRLLEALDNPQDKLPPVIHLAGTNGKGSTQAMI
RAGLEGMGKRVHAYTSPHLARFHERIRLAGELISEEHLTEVLDECYARNGGENITYFEIT
TVAGLLAFSRTPADYTLLEVGLGGRLDATNVITPALSVITPVSIDHEQFLGNTLAKIAGE
KAGIIKRGVPVVVGPQPDEAMEVIEATAARLGAPLIAYGQHWHVWEERGRLVFQDETGLL
DLPLPVLLGAHQIQNAGAALAALRHLGADEAACEAAMLHAEWPARMQKLKTGPLVEAAPE
AELWLDGGHNAAAGVALADVLAKLPERPTHLICGMLNTKDVRGYMAPLAPHVASLTAISI
PDEVNTLSAGETEAAARSVGIEAGTSESPLAALQAIIARDPQARVLICGSLYLAGHILRE
NG

NT seq 1269 nt +upstreamnt +downstreamnt
atgacccagacctccgacgcgatcctcgcccgcatgatggcgctgcaccccaagatcatc
gacctgacgctggaccgggtctggcggctgctggaagcgctggacaacccgcaggacaag
ctgccgccggtgatccatctggcgggcaccaacggcaaaggctcgacccaggcgatgatc
cgggcggggctggaggggatgggcaagcgcgttcatgcctatacctcgccgcatctggcg
cgctttcacgagcggatccggctggcgggcgagctgatctcggaagagcatctcaccgag
gtgctggacgagtgctatgccaggaacggcggcgaaaacatcacctatttcgagatcacc
acggtggcggggctgctggcgttttcccgcacgcctgcggattacacgctgctggaggtc
ggcctgggcgggcggctggatgcgaccaatgtgatcaccccggcgctcagcgtgatcacc
ccggtttcgattgaccatgaacagttcctgggcaacacgctggcgaagatcgcaggcgaa
aaggcgggcatcatcaagcgcggcgtgccggttgtggttggcccgcagcctgacgaggcg
atggaggtgatcgaggccactgctgcacgcctcggcgcgccgctgatcgcctatggccag
cactggcatgtctgggaggagcgcgggaggctggtgtttcaggacgaaaccggcctcttg
gatttgccgctgccggttctgctgggcgcgcatcagatccagaacgccggtgcggcgctg
gcggcgctgcgccatctgggtgccgatgaggcggcttgcgaagcggcgatgctgcacgcc
gaatggcccgcgcggatgcagaaactgaagaccggcccgctggttgaggccgcgccggag
gcggagctgtggctggacggcggccacaacgccgcggcgggcgtggcgctggcggatgtt
ctggccaagctgccggagcgccccacgcatctgatctgcggcatgctgaacaccaaggat
gtgcgcggctacatggccccgctggccccgcatgttgcaagcctgacggcgatctcgatc
cccgatgaggtgaacacgctgagcgccggggagaccgaggccgcggccagatcggtgggc
atcgaggcgggcacttcggaaagcccgctggcggcgctgcaggcgatcatcgccagggac
ccgcaggcgcgggtgctgatctgcggctcgctgtatctggccggccacatcctgcgcgaa
aacggctga

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