Loxodonta africana (African savanna elephant): 100653931
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Entry
100653931 CDS
T04351
Symbol
PDHA2
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial isoform X1
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
lav
Loxodonta africana (African savanna elephant)
Pathway
lav00010
Glycolysis / Gluconeogenesis
lav00020
Citrate cycle (TCA cycle)
lav00620
Pyruvate metabolism
lav00785
Lipoic acid metabolism
lav01100
Metabolic pathways
lav01200
Carbon metabolism
lav01210
2-Oxocarboxylic acid metabolism
lav04066
HIF-1 signaling pathway
lav04922
Glucagon signaling pathway
lav05230
Central carbon metabolism in cancer
lav05415
Diabetic cardiomyopathy
Module
lav_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
lav00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
100653931 (PDHA2)
00020 Citrate cycle (TCA cycle)
100653931 (PDHA2)
00620 Pyruvate metabolism
100653931 (PDHA2)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
100653931 (PDHA2)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
100653931 (PDHA2)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
100653931 (PDHA2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
100653931 (PDHA2)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
100653931 (PDHA2)
Enzymes [BR:
lav01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
100653931 (PDHA2)
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Paralog
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Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
DUF2284
Motif
Other DBs
NCBI-GeneID:
100653931
NCBI-ProteinID:
XP_003410493
UniProt:
G3T1X0
LinkDB
All DBs
Position
Unknown
AA seq
392 aa
AA seq
DB search
MKKMLAAVVSRVLSGVATQKPSSRVLVASCNYSKQATFEIKKCDLYNLEEGPPVTAELTR
EDGLKYYRLMQTVRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLEAGIRHTDHVITSY
RAHGICVTRGIPVRAVLAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIA
LACKYKENKEICLTLYGDGAANQGQLFEAYNMAALWKLPCVFICENNRYGMGTAVERAAA
TPDYYKRGSFIPGLRVDGMDILCVREATKFAADYCRSGKGPILMELQTYRYHGHSMSDPG
ISYRSRQEIQDVRSKSDPIMLLKDKMVNSKLATVEEFKEIDGEVKKEIEDAAQFAITDPE
PPLEELGHHIYSSSPPFELRGANQWIKFKSIS
NT seq
1179 nt
NT seq
+upstream
nt +downstream
nt
atgaagaagatgctcgccgcagttgtctcccgtgtgttgtcgggcgtcgccacccagaag
ccgtccagcagagtgctggtggcatcctgtaactattcaaaacaggctacatttgaaatt
aagaaatgtgatctgtataatttggaagagggccctcctgtcacggcagagctcaccagg
gaggatgggctcaaatactaccggctgatgcagaccgttcgccgaatggagttaaaagca
gatcagctgtataagcagaaattcattcgtggtttctgccatttatgtgacggtcaggaa
gcgtgttgtgttgggcttgaggcaggtataagacacacggatcatgtcatcacatcctat
cgggcgcatggcatatgcgttactcggggaattcccgttcgagcagttcttgcagagctt
acaggacgaagaggaggttgtgctaaaggaaaaggtggatcaatgcatatgtatgccaag
aacttctacgggggcaacggcattgttggagctcaggtgcccctgggagctggtattgcc
ttggcctgtaaatataaggaaaacaaggagatctgtttgactttatatggagatggcgct
gctaatcagggtcagctatttgaagcttacaatatggcagctttgtggaaattgccttgt
gttttcatctgtgagaataaccgctatggaatgggaacagctgttgagagagcagcagcc
actcctgattattacaagagaggcagttttattccggggctaagggtagatggaatggat
attctgtgtgtccgggaggccacaaagttcgccgctgactattgtagatctggaaagggg
cccatactgatggagctgcagacttaccgttatcacggacacagtatgagtgatcctgga
atcagttatcgttcccggcaagaaattcaggatgtaagaagtaagagtgaccctattatg
cttctcaaagataaaatggtaaacagcaagcttgccactgtggaagaattcaaggaaatt
gatggtgaagtgaagaaagaaattgaggatgcggcccaatttgccataactgatccagaa
ccacccttggaggaattaggccatcacatctacagcagtagtccaccttttgaacttcgt
ggtgcaaatcagtggatcaagtttaaatcgatcagttaa
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