Loxodonta africana (African savanna elephant): 100655118
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Entry
100655118 CDS
T04351
Symbol
POLE
Name
(RefSeq) DNA polymerase epsilon catalytic subunit A isoform X1
KO
K02324
DNA polymerase epsilon subunit 1 [EC:
2.7.7.7
]
Organism
lav
Loxodonta africana (African savanna elephant)
Pathway
lav03030
DNA replication
lav03410
Base excision repair
lav03420
Nucleotide excision repair
Brite
KEGG Orthology (KO) [BR:
lav00001
]
09120 Genetic Information Processing
09124 Replication and repair
03030 DNA replication
100655118 (POLE)
03410 Base excision repair
100655118 (POLE)
03420 Nucleotide excision repair
100655118 (POLE)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
lav03032
]
100655118 (POLE)
03400 DNA repair and recombination proteins [BR:
lav03400
]
100655118 (POLE)
Enzymes [BR:
lav01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.7 Nucleotidyltransferases
2.7.7.7 DNA-directed DNA polymerase
100655118 (POLE)
DNA replication proteins [BR:
lav03032
]
Eukaryotic type
DNA Replication Elongation Factors
DNA polymerase epsilon complex
100655118 (POLE)
DNA repair and recombination proteins [BR:
lav03400
]
Eukaryotic type
SSBR (single strand breaks repair)
BER (base exicision repair)
Long Patch-BER factors
DNA polymerase epsilon complex
100655118 (POLE)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DUF1744
DNA_pol_B_exo1
DNA_pol_B
DNA_pol_B_exo2
RNase_H_2
APP_N
DUF4085
Motif
Other DBs
NCBI-GeneID:
100655118
NCBI-ProteinID:
XP_003421306
LinkDB
All DBs
Position
Unknown
AA seq
2283 aa
AA seq
DB search
MVLHNSGRRRAEPSADGEASRDDGPSSSVSALKRLERSQWTDKMDLRFGFQRLKEPGEKT
GWLINMHPTEVLDEDKRLVSAVDYYFIQDDGSRFKVALPYKPYFYIATRKGCEREVSSFL
SRKFQGKIAKVETVPKEDLDLPNHLVGLKRNYIKLSFNTVEDLVKARKEISPAVRKNREQ
DHASDTYTAMLSSVLQGGGVITDEEETSKKIADQMDNIVDMREYDVPYHIRLSIDLKIQV
AHWYNVRYRGSAFPVEITRRDDLVERPDPVVLAFDIETTKLPLKFPDAETDQIMMISYMI
DGQGYLITNREIVSEDIEDFEFTPKPEYEGPFCVFNEPDEVHLIQRWFEHVQETKPTIMV
TYNGDFFDWPFVEARAAVHGLSMYQEIGFQKDSQGEYKAPQCIHMDCLRWVKRDSYLPVG
SHNLKAAAKAKLGYDPVELDPEDMCRMAAEQPQTLATYSVSDAVATYYMYMKYVHPFIFA
LCTIIPMEPDEVLRKGSGTLCEALLMVQAFHANIIFPNKQEQEFNKLTDDGHVLDAETYV
GGHVEALESGVFRSDIPCRFRMNPAAFDFLLQRVEKTMHHAIEEEEKVPMEQVTNFQEVC
DQIKTRLTSLKDVPNRIECPLIYHLDVGAMYPNIILTNRLQPSAMVDEATCAACDFNKPG
ANCQRKMAWQWRGEFMPASRSEYHRIQHQLESEKFPPLIPEGPTRAFHELSREEQAKYEK
RRLADYCRKAYKKLHVTRVEQRLTTICQRENSFYVDTVRAFRDRRYEFKGLHKVWKKKLS
AAMEMGDAAEVKRCKNMEILYDSLQLAHKCILNSFYGYVMRKGARWYSMEMAGIVCFTGA
NIITQARELIEQIGRPLELDTDGIWCVLPNSFPENFVVKTTNVKKPKVTISYPGAMLNIM
VKEGFTNHQYQELAEPSSLTYVTHSENSIFFEVDGPYLAMILPASKEEGKKLKKRYAVFN
EDGSLAELKGFEVKRRGELQLIKIFQSSVFEAFLKGSTLEEVYGSVAKVADYWLDVLYSK
AANMPDSELFELISENRSMSRKLEDYGEQKSTSISTAKRLAEFLGDQMVKDAGLSCRYII
SRKPEGSPVTERAIPLAIFQAEPTVRKHFLRKWLKSSSLQEFDIRTILDWDYYIERLGSA
IQKIITIPAALQQVKNPVPRVRHPDWLHKKLLEKNDVYKQKKISELFVLEGKRQVVMNQA
PEGSRSPGPPDVEDFGLMKPPHAAVPVVTRRKRVLWESQEESQELELTVPWQDILGQPPA
LGTTQEEWLVWLRFHKKKWQLQARQRLARRKRQRLEGTESAPKAGALREGPTTALGSFLR
RTARSILDLPWQIVQISETSQPGLFRLWAVIGSDLYCIRLSIPRVFYVNQRVAKAEEGPS
YRKVNRVLPRANVVHHLYEYSVPEDMYQEHINEINTELSAPDIEGVYETQVPLLFRALVQ
LGCVCVVNKQLVRHLSGWEAETFALEHLEMRSLAQFSYLEPGSIRHLYLYHHAQGHKALF
GVFIPTQRRASVFVLDRVRSNQMPNLSAMYASEHSLLLEQVGSEFLPPPKHTFEVRAETD
LKTICRAIQRVLLAYKEERRGPTVVAVQSSWELRRLAGEVPVLEEFPLVPVRVTDKVSYA
VLDWQRHGARHMIRHYLHLDTCLSQAFEMSRYFHIPVGNLPEDISTFGSDLFFARHLQRH
SHLLWLSPTSRPDLGGKEADDSRLVMELDDHATVEINSSGCYSTVCVELDIQNLAVNTVL
QSHRVNDMEGAASAGISFDAIPQASLEDMITGNQATSMPASYDETALCSSTFRILKNMVV
GWVKEITQYHNVYADNQVMHFYRWLRSPSSLLHDPALHRTLHSMMKKLFLQLIAEFKRLG
SSVVYANFNRIILCTKKRRIEDALAYVEYITNSIHSKEIFHSLTISFSRCWEFLLWMDPS
NYGGIKGKVSPSIHCGQRESLEGEEAEREQEEEEEEEEEEEEGLEEARVEDLLENNWNIL
QFLPQAASCQSYFLMIVSAYIVAVYHSMKEELRRNAPGSTPVKRRGASQFSQETEGAAGA
LPGTITFSQDYVANELTQNFFTITQKIQKKVTGFRNSTEPSEMFPQLPGSHLLLNNPALE
FIKYVCKVLSLDTNITNQVNKLRRDLLRLVGVGEFSPEAQFRDPCRSHVLSEVICHSCNF
CRDLDLCKDSAFSQDGAVLPQWLCSNCEVPYDSTVIEAALVDALQKKLMAFTLQDLVCLK
CAGVKETHMPVHCSCAGDFALTVHTKVFMEQIRIFRNIAQHFSMSYLLEILEWLLQETPP
PGH
NT seq
6852 nt
NT seq
+upstream
nt +downstream
nt
atggttctgcacaacagcgggcggcggcgcgcggagccgagcgcggacggcgaggccagc
cgggatgacgggccctcttcttcagtctcggcactcaagcgcttggagcgaagtcagtgg
acagataagatggatttgcggtttggttttcagaggctgaaggagcctggagagaagaca
ggctggctcatcaacatgcatcctactgaggttttagatgaagataagcgcttagtcagt
gcagtagattactactttattcaagacgatgggagcagatttaaggtggcgttaccctat
aagccatatttctacattgcaaccagaaagggctgtgaacgagaagtttcatcttttctc
tccaggaagtttcagggtaaaattgctaaagtggagactgtccccaaagaagatctggac
ttgccaaatcatttagtgggtttgaagcgaaattacattaaactgtcctttaacacggtt
gaggatcttgtcaaagcgaggaaggagatttcccctgcagtgaggaagaaccgagagcag
gaccatgccagcgacacctacacggctatgctctccagtgttctgcaagggggcggagta
attactgatgaagaggaaacctctaaaaagatagctgaccagatggacaacattgtggac
atgcgagagtatgatgtcccataccacatccgcctttccattgacctgaagatccaagtg
gctcactggtataacgtcaggtacagaggcagtgcctttccggtggaaatcacccgccga
gatgaccttgttgaacgacctgaccctgtagttttggcatttgacattgaaacaaccaaa
ttacctctcaagtttcctgatgctgagactgaccagattatgatgatttcttacatgatt
gatgggcagggttacctgatcactaacagggagattgtttcggaagatatcgaagatttt
gagttcacccccaagccagaatatgaagggccgttctgtgtcttcaatgaacctgatgag
gttcatctcatccagaggtggtttgagcatgtgcaggagaccaagcccaccatcatggtg
acctacaatggagacttctttgactggccatttgtggaggccagagcggctgtgcatgga
ctgagcatgtaccaggagatagggttccagaaggacagccagggggaatacaaggccccc
cagtgcatccacatggactgcctcaggtgggtgaagcgggacagttaccttcctgtgggc
agccacaacctcaaggcggccgccaaagccaagctgggctacgaccctgtggagctggac
cccgaggacatgtgccggatggccgccgagcagccccagaccctggccacgtactcggtg
tcggacgcagtggccacctactacatgtacatgaagtatgtccaccccttcatcttcgcg
ctgtgcaccatcatccccatggaacccgatgaggtgctgcggaagggatcaggaactctg
tgtgaggccttgctgatggtccaggcgttccatgccaacatcatcttccccaacaagcaa
gagcaggagtttaataagctgacggacgatggccatgtgctggatgctgagacctacgtg
ggcggccacgtggaggccctcgagtcaggcgtgttccgcagcgacatcccctgccggttc
aggatgaaccctgctgcctttgatttcctgctgcagcgggtcgagaagaccatgcaccat
gccatcgaggaggaggagaaggtgcccatggagcaggtcaccaacttccaagaggtctgt
gaccagatcaagaccaggctcacctccctgaaagatgttcctaatcgaattgagtgcccc
cttatttaccatctggacgtgggggccatgtaccccaatatcatcctcaccaaccgcctg
cagccctccgccatggtggatgaggccacctgtgctgcttgtgactttaacaagcctgga
gcaaactgccagcgaaagatggcctggcagtggaggggcgaattcatgccggccagccgc
agtgaataccaccgcatccagcaccagttggagtcggagaagttccctcccctgatccca
gaagggcccacccgagcatttcacgaactgtcccgggaggagcaggccaagtatgagaag
cggaggctggcagattattgccggaaggcatacaagaagctccacgtcacccgggtggag
cagcgcctcaccacaatctgccagcgggagaactccttctatgtggacacggttcgcgcc
ttccgggaccggcgctatgagttcaaagggctgcacaaggtgtggaagaaaaagctgtct
gcagcgatggagatgggtgatgcagctgaggtgaagcgctgcaagaacatggagatcctg
tacgactccctgcagctggcccacaagtgcatcctcaactccttctatggctacgtcatg
cgcaagggggcgcgttggtactccatggagatggccggcatcgtctgcttcacgggggcc
aatatcattacccaggcccgggagctcattgagcagattgggaggcccttggagctggac
acagatggaatatggtgtgtcctgcccaatagttttccagaaaactttgttgtcaagact
accaacgtgaagaagcccaaggtgaccatttcttaccctggggccatgctaaacatcatg
gtcaaggagggcttcaccaaccaccagtaccaggagctggcagagccctcttcgctgacc
tacgtcacccattctgagaacagcatcttctttgaagtcgacgggccctacctagccatg
atcctcccggcctccaaggaagaaggcaagaagctcaaaaagaggtacgctgtgttcaat
gaggatggatccctggcggagctcaagggctttgaggtcaagcggcgcggggagctgcag
ctgattaagattttccagtcctcggtgtttgaggccttcctcaaaggcagcacgctggag
gaggtgtatggctcggtagccaaggtggccgactactggctggacgtgctgtacagcaag
gcagccaacatgccagattcggagctgtttgagctcatctctgagaaccgctccatgtct
cggaagctggaggactacggagagcagaagtcgacctccatcagcacggccaaacgcctg
gccgagttcctgggcgaccaaatggtcaaggatgcagggctgagctgccgctacatcatc
tcccggaaacccgagggctcgcctgtcacggagagggccatccccctggccatcttccag
gcagagcccacagtgaggaagcactttctccggaaatggctcaagagttcttccttgcag
gagtttgatattcggacgattctggattgggactactacatcgagcgactgggaagtgcc
atacagaagatcatcacaattcctgcagctctgcagcaggtgaagaacccggtgccgcga
gtcagacaccccgactggctgcacaagaagctgctggagaagaacgacgtctacaagcag
aagaagatcagcgagttgtttgtcctcgagggcaagagacaggtcgtaatgaaccaggct
ccagaaggcagtcggagccctggacctcctgacgtggaagacttcggcctcatgaagcct
ccgcatgcagcagttcccgttgttactagaaggaagcgggtcctttgggagagccaggag
gagtcccaggaactggagctgacagtgccctggcaggacatcttgggacaaccccctgca
cttggtaccacccaggaagagtggcttgtgtggctccgattccacaagaagaagtggcag
ctgcaggcccggcagcgccttgcgcgcaggaagaggcagcgtctcgagggcactgagagt
gcaccaaaggctggagcactccgcgaggggcccaccacggccctgggaagcttcctgcgg
aggactgcccgcagcatcctggacctcccctggcagatagtgcagatcagcgagaccagc
cagcccggcctgttccggctgtgggctgtcattggcagcgacctgtactgtatcaggctg
agcatcccgcgtgtgttctacgtgaaccaacgggtggcgaaagcagaggaggggccctca
tatcgcaaggtaaaccgcgtgctccctcgtgccaacgtggtccaccacctctacgagtac
tcagtgcctgaggacatgtaccaggagcacatcaacgaaatcaacacggagctgtcggcg
ccggacattgagggcgtctatgagactcaggtgccactgctgttccgggccctggtgcag
ctcggctgtgtgtgtgtggtgaacaagcagctagtgaggcacctctccggctgggaagca
gaaacctttgcccttgagcacctggagatgcgttctctggcccagttcagctacctggaa
ccagggagcatccgccacctctacctgtatcaccatgcgcaaggccacaaggcgctcttt
ggggttttcatccccacgcagcgcagggcatccgtgttcgtgctggacagggtgcgtagc
aaccagatgccaaacctcagtgccatgtacgcctccgagcacagcctcctgctggagcag
gtgggctccgagttcttgcctcctcccaagcacaccttcgaggttcgagcagagaccgac
ttgaagaccatctgcagagcgatccagcgcgtcctgcttgcctacaaggaagagcgccgt
gggcccacagtggttgctgtgcagtccagctgggagctgaggaggttggcgggcgaggtt
cctgtgctggaggagttccccctggtgccagtgcgggtgactgataaggtcagctacgca
gtcctggattggcagcgccatggggcgcggcacatgattcgacactaccttcacctggac
acctgcctatcccaggcatttgagatgagcaggtatttccacattcctgtcgggaacctt
ccggaggacatctctacctttggctctgacctcttctttgcccgccacctccagcgccac
agccacctcctctggctctcccccacatcccggcctgacctgggtggcaaggaggctgat
gatagccgcctggtcatggagctcgatgaccacgccacagtggagatcaacagctcgggc
tgctactccacagtgtgtgtggagctggacatccagaaccttgctgtcaacaccgtcctc
cagtcgcaccgggtcaacgacatggagggggccgccagtgcaggcatcagctttgacgcg
atcccgcaggcctccctggaggacatgatcactggcaaccaggccacctccatgccagcc
agctatgacgagacggccctctgctccagcaccttcaggatcctgaagaacatggtggta
ggctgggtgaaggagatcacgcagtaccacaacgtttacgccgacaaccaggtgatgcac
ttctaccggtggctgcggtccccgtcctccctgctgcacgaccccgccctgcaccgcaca
ctacacagcatgatgaagaagctgttcctgcagctcattgctgagttcaagcgcctgggg
tcgtcagtcgtttatgccaacttcaatcgcatcatcctctgcacaaagaagcgccgcatc
gaggacgcccttgcctacgtggagtacatcaccaacagcatccactctaaagagatcttc
cattccttgacaatttctttctctcgatgctgggaatttcttctctggatggatccatct
aactacgggggaatcaaaggaaaagtctcaccaagtattcactgtggacagcgagagtct
ctggaaggggaggaagcagaaagagagcaggaggaagaggaggaggaggaggaggaggaa
gaggaaggcttggaggaagccagagtggaggatttactggagaacaactggaacattttg
cagtttttgccacaagcagcctcctgccaaagctactttctcatgatcgtctcagcgtat
atcgtggccgtgtaccacagcatgaaagaggagctgaggcgcaatgccccagggagcacc
ccagtgaagaggagaggggccagccagttctcccaggagacggagggtgcagctggggcc
ctacctggaacgatcaccttctctcaggactatgtggcaaatgagctcacccaaaacttc
ttcaccatcacgcagaagattcagaagaaagtcacaggctttcggaactccacggagccc
tcagagatgttccctcagctcccgggctctcacctgctgcttaacaacccagcgctggag
ttcatcaagtatgtgtgcaaggtgctgtccctggacacgaacatcacaaaccaggtgaac
aagctgcgccgggacctgctgcgcctggtgggtgtcggcgagttctcaccagaggcacag
ttccgagacccctgccgctcgcacgtgctctcagaggtcatctgccacagctgcaatttc
tgccgggacttggacctgtgcaaagactccgcattctcccaggacggggcagtccttcct
cagtggctctgttccaactgtgaggtgccctacgactccaccgtcattgaggcagccctg
gtggacgcactgcagaagaagctgatggccttcacgctgcaggacctggtctgcctgaag
tgtgctggtgtcaaggagacccacatgcctgtccactgcagctgtgcaggcgacttcgcc
ctcaccgtccataccaaggtcttcatggagcagatcagaattttccggaacattgcccag
cacttcagcatgtcttacctgctggagattctggagtggctgctgcaggagacccctcca
ccaggccactag
DBGET
integrated database retrieval system
