Loxodonta africana (African savanna elephant): 100656603
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Entry
100656603 CDS
T04351
Symbol
ACACA
Name
(RefSeq) LOW QUALITY PROTEIN: acetyl-CoA carboxylase 1
KO
K11262
acetyl-CoA carboxylase / biotin carboxylase 1 [EC:
6.4.1.2
6.3.4.14
2.1.3.15
]
Organism
lav
Loxodonta africana (African savanna elephant)
Pathway
lav00061
Fatty acid biosynthesis
lav00620
Pyruvate metabolism
lav00640
Propanoate metabolism
lav01100
Metabolic pathways
lav01212
Fatty acid metabolism
lav04152
AMPK signaling pathway
lav04910
Insulin signaling pathway
lav04922
Glucagon signaling pathway
lav04936
Alcoholic liver disease
Module
lav_M00082
Fatty acid biosynthesis, initiation
Brite
KEGG Orthology (KO) [BR:
lav00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
100656603 (ACACA)
00640 Propanoate metabolism
100656603 (ACACA)
09103 Lipid metabolism
00061 Fatty acid biosynthesis
100656603 (ACACA)
09110 Biosynthesis of other secondary metabolites
00254 Aflatoxin biosynthesis
100656603 (ACACA)
09130 Environmental Information Processing
09132 Signal transduction
04152 AMPK signaling pathway
100656603 (ACACA)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
100656603 (ACACA)
04922 Glucagon signaling pathway
100656603 (ACACA)
09160 Human Diseases
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
100656603 (ACACA)
Enzymes [BR:
lav01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.3 Carboxy- and carbamoyltransferases
2.1.3.15 acetyl-CoA carboxytransferase
100656603 (ACACA)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.4 Other carbon-nitrogen ligases
6.3.4.14 biotin carboxylase
100656603 (ACACA)
6.4 Forming carbon-carbon bonds
6.4.1 Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
6.4.1.2 acetyl-CoA carboxylase
100656603 (ACACA)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
ACC_central
Carboxyl_trans
CPSase_L_D2
ACCA_BT
Biotin_carb_N
Biotin_carb_C
Biotin_lipoyl
ATP-grasp
Dala_Dala_lig_C
ATP-grasp_3
MetallophosN
Motif
Other DBs
NCBI-GeneID:
100656603
NCBI-ProteinID:
XP_023409148
LinkDB
All DBs
Position
Unknown
AA seq
2373 aa
AA seq
DB search
MWWSTLMSVLRASSFWRWISAQTIRITRALRTHFEGMMDEPTAMAKPVELNQHSRFIIGS
VSEDNSEDEISNLVKLDLLEEKEGSLSPASVSSDTLSDLGISGLQDGLALQMRSSMSGMY
LVKQGRDRKKIDSQRDFTVASPAEFVTRFGGNKVIEKVLIANNGIAAVKCMRSIRRWSYE
MFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPGGPNNNNYANVELILDIAKRIPVQ
AVWAGWGHASENPKLPELLLKNSIAFMGPPSQAMWALGDKIASSIVAQTAGIPTLPWSGS
GLRVDWQENDFSKRILNVPQELYEKGYVKDVDDGLKAAEEVGYPVMIKASEGGGGKGIRK
VNNADDFPNLFRQVQAEVPGSPIFVMRLAKQSRHLEVQILADQYGNAISLFGRDCSVQRR
HQKIIEEAPAAIATPVVFEHMEQCAVKLAKMVGYVSAGTVEYLYSQDGSFYFLELNPRLQ
VEHPCTEMVADVNLPAAQLQIAMGIPLYRIKDIRMMYGVSPWGDAPIDFENSAHVPCPRG
HVIAARITSENPDEGFKPSSGTVQELNFRSNKNVWGYFSVAAAGGLHEFADSQFGHCFSW
GENREEAISNMVVALKELSIRGDFRTTVEYLIKLLETESFQFNRIDTGWLDRLIAEKVQA
ERPDTMLGVVCGALHVADVSLRNSISNFLHSLERGQVLPAHTLLNTVDVELIYEGVKYVL
KVTRQSPNSYVVIMNGSCVEVDVHRLSDGGLLLSYDGSSYTTYMKEEVDRYRITIGNKTC
VFEEGEXPSVIRSPSAGKLIQYIIEDGGHVFAGQCYAEIEVMKMVMTLTAAESGCIHYVK
RPGAALDPGCVIAKLQLDNPSKVQQAELHTGSLPQIHSTALRGEKLHRVFHYVLDNLVNV
MNGYCLPDPFFSSKVKDWVERLMKTLRDPSLPLLELQDIMTSVSGRIPPNVEKSIKKEMA
QYASNITSVLCQFPSQQIANILDSHAATLNRKSEREVFFMNTQSIVQLVQRYRSGIRGHM
KAVVMDLLRQYLRVETQFQNGHYDKCVFALREENKSDMNTVLNYIFSHAQVTKKNLLVTM
LIDQLCGRDPTLTDELLNILTELTQLSKTTNAKVALRARQVLIASHLPSYELRHNQVESI
FLSAIDMYGHQFCIENLQKLILSETSIFDVLPNFFYHSNQVVRMAALEVYVRRAYIAYEL
NSVQHRQLRDNTCVVEFQFMLPTSHPNRGNIPTLNRMSFSSNLNHYGMTHVASVSDVLLD
NSFTPPCQRMGGMVSFRTFEDFVRIFEEVMGCFCDSPPQSPTFPEAGHTSLYDEDKVPRE
EPIHILNVAIKTDCDIEDDRLAAMFREFTQQNKATLVEHGIRRLTFLVAQKDFRKQVNCE
VDQRFHREFPKFFTFRARDKFEEDRIYRHLEPALAFQLELNRMRNFDLTAIPCANHKMHL
YLGAAKVEVGTEVTDYRFFVRAIIRHSDLVTKEASFEYLQNEGERLLLEAMDELEVAFNN
TNVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMRYGSRLWKLRVLQAELKINIRLTPTG
KAIPIRLFLTNESGYYLDISLYKEVTDSRTAQIMFQAYGDKQGPLHGMLINTPYVTKDLL
QSKRFQAQSLGTTYIYDIPEMFRQSLIKLWESMTTQAFLPSPPLPSDILTYTELVLDDQG
QLVHMNRLPGGNEIGMVAWKMTLKSPEYPEGRDIIVIGNDITYQIGSFGPQEDLLFLRAS
ELARAEGIPRIYVAANSGARIGLAEEIRHMFHVAWVDPEDPYKGYKYLYLTPQDYKRVSA
LNSVYCEHVEDEGESRYKITDIIGKEEGLGAENLRGSGMIAGESSLAYDEIITISLVTCR
AIGIGAYLVRLGQRTIQVENSHLILTGAGALNKVLGREVYTSNNQLGGIQIMHNNGVTHS
TVCDDFEGVFTVLHWLSYMPKSVYSSVPLLNSKDPIDRIIEPLFSFFFPSVAQKGQWLSG
FFDYGSFSEIMQPWAQTVVVGRARLGGIPVGVVAVETRTVELSIPADPANLDSEAKIIQQ
AGQVWFPDSAFKTYQAIKDFNREGLPLMVFANWRGFSGGMKDMYDQVLKFGAYIVDGLRK
CSQPVMVYIPPQAELRGGSWVVIDPTINPRHMEMYADRESRGSVLEPEGTVEIKFRKKDL
VKTMRRVDPVYIRLAERLGTPELSQAERNELENKLKEREEFLIPIYHQVAVQFADLHDTP
GRMQEKGVINDILDWKTSRTFFYWRLRRLLLEDLVKKKIHNANPELTDGQIQAMLRRWFV
EVEGTVKAYVWDNNKDLVEWLEKQLTEEDGVRSVIEENIKYISRDYVLKQIRSLVQANPE
VAMDSIVHMTQHISPTQRAEVVRILSTMDSPST
NT seq
7122 nt
NT seq
+upstream
nt +downstream
nt
atgtggtggtccactctgatgtcagtcttgagggctagttctttttggaggtggatatct
gctcagacaataagaatcacaagagctctgagaactcattttgaaggaatgatggatgag
cccactgccatggccaaacctgtagagctgaaccagcactctcgattcataattggttct
gtgtctgaagataactcagaggatgagatcagcaacctggtaaagttggacctacttgaa
gaaaaggagggctctctgtcaccagcttctgtcagctcagatacactctctgatttggga
atctctggcctacaggatggcttggccttacagatgaggtccagcatgtctggtatgtac
ctagtgaaacagggtcgagaccgaaagaaaatagactcacagcgagatttcactgtggct
tctccagcagaatttgttactcgttttgggggaaataaagtgattgagaaggttcttatt
gccaacaatggaattgcagcagtgaaatgcatgcggtctattcgtcggtggtcttatgag
atgtttcgaaatgagcgtgcaatccggtttgttgtcatggtcacacctgaagaccttaaa
gccaatgcagaatacattaagatggcagatcactatgtgccagtgcctggaggaccaaac
aacaacaactatgcaaatgtagaattaattctcgatattgctaaaaggatcccagtacaa
gcagtgtgggctggctggggtcatgcttctgagaatcccaagctcccggaacttctcttg
aaaaatagcattgccttcatgggtcctccgagccaggctatgtgggctttgggggataag
attgcatcttccatcgtggctcaaacagcaggtatcccaactcttccctggagtggcagt
ggtcttcgtgtggactggcaggaaaatgatttttcgaaacgtatcttaaatgttccccag
gaactgtacgagaaaggttatgtgaaggatgtagatgatgggttgaaggcagcggaagaa
gttggatatccagtaatgatcaaggcttcagaaggaggaggagggaagggaatccgaaaa
gtcaacaatgcagatgacttccctaacctcttcagacaggttcaagctgaagtccctgga
tcacctatatttgtgatgagactagccaaacagtctcgtcacttggaggtgcagatccta
gcagatcagtatggcaatgccatctctttgtttggtcgtgactgctctgtacagcgcagg
caccagaaaattattgaagaggcacctgctgctattgctactccagtggtatttgaacat
atggaacagtgtgcggtgaaacttgccaaaatggttggttatgtgagtgctgggactgtg
gagtacctctacagccaggatggcagcttctactttttggaactgaaccctcggctacag
gtggagcacccttgtacagagatggtggctgatgtcaacctccccgcagcacaactccag
attgccatggggatccctctatatagaatcaaggatatccgtatgatgtatggggtatct
ccctggggcgatgctcccattgattttgaaaattctgctcatgttccttgcccaaggggc
catgttattgctgctcggatcactagtgaaaatccagatgagggttttaagcccagctca
ggaacagttcaggagttgaatttccgcagcaataagaacgtttggggttatttcagtgtt
gctgccgcagggggacttcatgaatttgctgattctcagtttggtcactgcttttcctgg
ggagaaaacagagaggaagcaatttcaaatatggtagtggctttgaaggagctgtctatt
cggggtgattttcgaactacagttgaatacctgatcaaattgttggagactgaaagcttt
cagttcaatagaattgacactggttggctggacagactgatagccgaaaaagtacaggca
gagagacctgacaccatgttgggagttgtgtgtggagctctccacgtggcagatgtgagc
ctgcggaatagcatctctaacttccttcactccttagaaaggggtcaagtccttccagct
cacacacttctgaatacagtagatgtggaacttatctatgagggggtgaagtatgtactt
aaggtgactcgacagtcccccaactcctacgtggtgatcatgaatggctcatgtgtggaa
gtagatgtgcatcggctaagtgatggaggactgctcttgtcctatgatggtagcagctat
accacatacatgaaggaggaagtagataggtatcgcattacaattggcaataaaacctgt
gtatttgaagaaggagaatgaccatcagtgatccgctcaccttctgctgggaagctaatc
cagtacattatagaggatggaggccatgtgtttgctggccagtgctatgctgagattgag
gtgatgaagatggtgatgactttgacagctgcagagtctggctgtatccattatgtcaag
cggcctggagcagctcttgaccctggctgtgtaatagccaaattgcagctggacaacccc
agcaaggtccagcaggctgagcttcacacaggtagtctgccacagatccacagcacagcc
ctcagaggcgagaagctccatcgagttttccactatgtcctggataatctggtcaacgta
atgaatggatactgccttccagatcctttctttagcagcaaggtaaaagactgggtagag
cgattgatgaagacactcagagatccctccctgcctctcctagaattgcaagatatcatg
accagtgtctctggccgtatccccccaaacgtggagaagtctatcaagaaggaaatggct
cagtatgctagcaacattacatcagtcctctgtcagtttcccagccaacagattgccaat
atcctagatagccatgcagctacactgaaccggaaatctgagcgagaagtcttcttcatg
aacactcagagcattgtacagctggtccagaggtatcgaagtggcatccgaggccatatg
aaggctgtggtgatggatctgctccggcagtacctgcgagtggagactcaattccagaat
ggtcactatgacaaatgtgtgttcgccttacgggaggagaacaagagtgacatgaacact
gtactgaactacatcttctctcatgctcaagtcaccaagaagaatcttctggtcacaatg
cttattgatcagttgtgtggccgagaccctactctcactgatgagctgctgaatatcctc
acagagctaacccaactcagtaagactaccaatgctaaagtggcacttcgagcacgccag
gttcttattgcctcccatttgccgtcatatgagcttcgccataaccaagtagagtctatc
ttcctatcagctattgacatgtacggacatcagttttgcattgagaacctgcagaaactc
atcttgtctgaaacatctatttttgatgtcctacccaacttcttctatcacagcaaccag
gtagtgaggatggcagctctggaggtgtatgttcgaagggcttatattgcctatgaactt
aacagcgtacaacaccgccagcttagagacaacacctgcgtggtggaatttcagttcatg
ctgcccacatctcatccaaatagagggaacatccccacgctaaacagaatgtccttctcc
tccaacctcaaccactatggcatgactcatgtagctagtgtcagcgatgtgctcttggac
aactcattcactccaccatgtcagcggatgggcggaatggtctcttttcggactttcgaa
gattttgtcaggatctttgaagaagtgatgggctgcttctgtgactccccaccccaaagc
cccacattccctgaggcaggtcacacatctctatatgatgaagacaaggtccccagggaa
gagccaattcacattctgaatgtagctatcaagactgactgtgatattgaggatgacaga
ctggcagctatgttcagagagtttacccagcaaaataaagctaccctggttgagcatgga
atccggcgccttacattcctggttgcgcaaaaggatttcaggaaacaggtcaactgtgag
gtggatcagagatttcatagagaattccctaaatttttcacattccgtgcaagggataag
tttgaagaggatcgtatatatcgtcacctggagcctgccctggcttttcagttggaactg
aaccggatgagaaattttgacctcactgccatcccgtgtgctaatcacaagatgcacctg
tatcttggggcagccaaggtggaagtgggcacagaagtgacagactataggttctttgtg
cgggcaatcatcagacattctgacctggtcaccaaggaagcttcttttgaatatctacaa
aacgaaggggagcggctgctcctggaagccatggatgagttggaagtggcttttaacaat
acaaatgtccgtactgactgtaaccacatcttcctcaactttgtgcccacagtcatcatg
gacccgtcaaagattgaggaatctgtgcggagcatggtaatgcgctatggaagtcgtctg
tggaaattgcgcgtcctccaggcagaactgaaaatcaacattcgcctgacaccaaccgga
aaagcaattcccatccgcctcttcctgacaaacgagtctggctattacttggacatcagc
ctgtacaaggaagtgactgactccaggacagcacagatcatgtttcaggcatatggagac
aaacagggaccactgcatggaatgttaatcaacactccatatgtgaccaaagacctgctt
caatcaaagaggttccaggcacaatccttagggaccacatacatttatgatatcccagag
atgtttcggcagtccctgatcaagctctgggagtctatgaccactcaagcattccttccg
tcacctccattgccttctgacatactgacgtatactgagctggtattggatgatcaaggt
cagctggtccacatgaacaggcttccaggaggaaatgagatcggcatggtagcttggaaa
atgacccttaaaagtcctgaatatccagaaggccgagatatcattgttattggcaatgac
ataacataccaaattgggtcctttgggccccaggaggatttgctgttcctcagagcgtct
gagcttgccagggcagaaggtatcccacgcatctatgtagcagccaacagtggagcaaga
attggactggcagaggaaattcgtcatatgtttcatgtggcctgggtagatcctgaggac
ccgtacaagggatacaagtatttatatctgacccctcaagattataagagagtcagtgct
ctcaactctgtctattgtgaacacgtggaggatgaaggagaatccaggtacaagataaca
gatattattgggaaggaagagggacttggcgcagagaatcttcgaggttctggaatgatt
gctggagaatcctcactggcctatgatgagatcatcaccatcagcctggtgacgtgtagg
gccattgggattggagcttaccttgtccggctgggacagagaaccatccaggttgagaat
tctcacttaattctgacaggagctggggcccttaacaaagtccttgggcgggaagtgtac
acctccaataaccagcttgggggcatccagatcatgcacaacaatggggtgacacacagc
accgtgtgtgatgacttcgaaggggttttcactgtcctgcattggctgtcttacatgcct
aagagtgtatacagttcagttcccctcctgaactccaaggatcctatagatagaatcatc
gagcctttgttttcttttttttttccttctgtagcccaaaaaggccagtggttgagtgga
ttttttgactatggatctttctcagagattatgcaaccctgggcacagactgtggtggtt
ggcagagctaggctaggaggaatacctgtgggagtagttgctgttgaaacccgaacagtt
gagctaagtatcccagctgatcctgcaaacctggattccgaagccaagataatccagcag
gccggccaggtttggttcccagactctgcatttaagacttaccaggctatcaaagacttc
aaccgtgaagggctgcctctgatggtctttgccaactggagaggcttctctggtgggatg
aaagatatgtacgaccaagtgctgaagtttggtgcttacattgtggacggcttacgcaag
tgttcccagcctgtgatggtttacattcctccccaggccgagctgcgaggtggctcctgg
gttgtgattgaccccaccatcaacccccggcacatggagatgtatgctgaccgagaaagc
aggggatcggttctggaaccagaagggacagtagaaatcaaattccgcaaaaaggatttg
gtgaaaaccatgcgtcgggtggaccccgtctacatccgcttggcggagcgattgggcacc
ccagagctaagccaagctgagcggaacgagctggagaacaagctgaaggagcgggaggaa
ttcctaattcccatttaccatcaggtagccgtgcagtttgctgacttgcatgacacacca
ggccggatgcaggagaagggtgttattaatgacatcctggattggaaaacatcccgtacc
ttcttctattggcggctgaggcgtctgctgctggaggacctagtcaagaagaaaatccac
aatgccaaccccgagctgactgatggccagatccaggccatgttgaggcgctggtttgtg
gaggtagaaggaactgtgaaggcctatgtttgggacaataataaggatctggtggaatgg
ctggagaaacagctgacagaggaagatggtgtccgctcagtgatagaggaaaacatcaaa
tatatcagcagagactatgtcctcaagcagatccgcagcttggtacaggccaacccagag
gtcgccatggattccatcgtccacatgactcaacacatctcacccactcagcgagcagaa
gttgtacggatcctgtccacgatggactccccttcaacatag
DBGET
integrated database retrieval system
