Loxodonta africana (African savanna elephant): 100660992
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Entry
100660992 CDS
T04351
Symbol
PDHA1
Name
(RefSeq) LOW QUALITY PROTEIN: pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
lav
Loxodonta africana (African savanna elephant)
Pathway
lav00010
Glycolysis / Gluconeogenesis
lav00020
Citrate cycle (TCA cycle)
lav00620
Pyruvate metabolism
lav00785
Lipoic acid metabolism
lav01100
Metabolic pathways
lav01200
Carbon metabolism
lav01210
2-Oxocarboxylic acid metabolism
lav04066
HIF-1 signaling pathway
lav04922
Glucagon signaling pathway
lav05230
Central carbon metabolism in cancer
lav05415
Diabetic cardiomyopathy
Module
lav_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
lav00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
100660992 (PDHA1)
00020 Citrate cycle (TCA cycle)
100660992 (PDHA1)
00620 Pyruvate metabolism
100660992 (PDHA1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
100660992 (PDHA1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
100660992 (PDHA1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
100660992 (PDHA1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
100660992 (PDHA1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
100660992 (PDHA1)
Enzymes [BR:
lav01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
100660992 (PDHA1)
BRITE hierarchy
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Ortholog
Paralog
GFIT
Motif
Pfam:
E1_dh
Motif
Other DBs
NCBI-GeneID:
100660992
NCBI-ProteinID:
XP_010594055
LinkDB
All DBs
Position
Unknown
AA seq
392 aa
AA seq
DB search
MRKMLAAVSRVLSGAAPKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTRED
GLRYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRA
HGFTFTRGLSVREILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVVYLWPXQGC
ARSLSCKKNNKMKALELFYEYFQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAA
STDYYKRGDFIPGLRVDGMDVLCVREATRFAAAYCRSGKGPILMELQTYRYHGHSMSDPG
VSYRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPE
PPLEELGHHIYSSEPPFEVRGANQWIKFKSVS
NT seq
1179 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagatgctcgctgctgtctcccgcgtgttgtcgggtgccgctccgaagccggct
agtagagtgctggttgcatcccgtaactttgcaaatgatgctacatttgaaattaagaaa
tgtgatctccatcggttggaagaaggcccccctgtcacaaccgtgctcaccagggaggat
gggctcagatactacaggatgatgcagactgtccgccgaatggaattaaaggcagatcag
ctgtataaacagaaaataatccggggcttctgccacttgtgtgatggtcaggaagcatgc
tgtgtggggctggaggccggtataaatcccaccgatcatctcattacagcctatcgggct
catggctttacctttactcgtggtctttctgtccgagaaatcctcgcagagctaacagga
cgaagaggaggttgtgctaaaggaaaaggaggctcaatgcatatgtatgccaagaacttc
tatgggggcaatggcattgtcggggctcaggtagtctatttatggccctgacaaggatgt
gcaagaagtttgagttgtaaaaaaaacaacaaaatgaaagcacttgaacttttttatgaa
tacttccagggtcagatatttgaagcttacaacatggcagctttgtggaaattaccttgt
attttcatctgcgagaataaccgctatggaatgggaacatctgtcgagagagcagcagcc
agcacagactactacaagagaggcgattttattcctgggctgagggtagatggaatggat
gtcctgtgtgtccgggaggctacaaggtttgcagctgcctattgcagatctggaaagggg
cccatactgatggagctgcagacttaccgttaccacggacacagtatgagtgatcctgga
gtcagttaccgtacacgagaagaaattcaggaagtgagaagtaagagtgatcctattatg
cttctcaaggatagaatggtgaacagcaaccttgccagtgttgaagagttaaaggaaatt
gatgttgaagtgaggaaggaaattgaggatgcggctcagtttgctacagctgatcctgaa
ccacctttggaagaattaggtcatcacatctactccagtgaaccaccttttgaagttcgt
ggtgcaaatcagtggatcaagtttaagtcagtcagttaa
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integrated database retrieval system
