Lemur catta (Ring-tailed lemur): 123620296 Help Entry 123620296         CDS       T08326                                  Symbol NOS2 Name (RefSeq) nitric oxide synthase, inducible   KO K13241   nitric-oxide synthase, inducible [EC:1.14.13.39] Organism lcat  Lemur catta (Ring-tailed lemur) Pathway lcat00220   Arginine biosynthesis lcat00330   Arginine and proline metabolism lcat01100   Metabolic pathways lcat04020   Calcium signaling pathway lcat04066   HIF-1 signaling pathway lcat04146   Peroxisome lcat04371   Apelin signaling pathway lcat04926   Relaxin signaling pathway lcat05010   Alzheimer disease lcat05014   Amyotrophic lateral sclerosis lcat05022   Pathways of neurodegeneration - multiple diseases lcat05133   Pertussis lcat05140   Leishmaniasis lcat05142   Chagas disease lcat05145   Toxoplasmosis lcat05146   Amoebiasis lcat05152   Tuberculosis lcat05200   Pathways in cancer lcat05222   Small cell lung cancer Brite KEGG Orthology (KO) [BR:lcat00001]  09100 Metabolism   09105 Amino acid metabolism    00220 Arginine biosynthesis     123620296 (NOS2)    00330 Arginine and proline metabolism     123620296 (NOS2)  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     123620296 (NOS2)    04066 HIF-1 signaling pathway     123620296 (NOS2)    04020 Calcium signaling pathway     123620296 (NOS2)  09140 Cellular Processes   09141 Transport and catabolism    04146 Peroxisome     123620296 (NOS2)  09150 Organismal Systems   09152 Endocrine system    04926 Relaxin signaling pathway     123620296 (NOS2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     123620296 (NOS2)   09162 Cancer: specific types    05222 Small cell lung cancer     123620296 (NOS2)   09171 Infectious disease: bacterial    05133 Pertussis     123620296 (NOS2)    05152 Tuberculosis     123620296 (NOS2)   09174 Infectious disease: parasitic    05146 Amoebiasis     123620296 (NOS2)    05145 Toxoplasmosis     123620296 (NOS2)    05140 Leishmaniasis     123620296 (NOS2)    05142 Chagas disease     123620296 (NOS2)   09164 Neurodegenerative disease    05010 Alzheimer disease     123620296 (NOS2)    05014 Amyotrophic lateral sclerosis     123620296 (NOS2)    05022 Pathways of neurodegeneration - multiple diseases     123620296 (NOS2) Enzymes [BR:lcat01000]  1. Oxidoreductases   1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen    1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor     1.14.13.39  nitric-oxide synthase (NADPH)      123620296 (NOS2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  NO_synthase FAD_binding_1 Flavodoxin_1 NAD_binding_1 Motif Other DBs NCBI-GeneID:  123620296 NCBI-ProteinID:  XP_045381365 LinkDB All DBs Position 15:19913860..19945100 Genome browser AA seq 1152 aa AA seqDB search MREGLGAACEAAGPRLCRLLRRILRPKPACRPRRASPVTQDDPKYHSLSKHQNESLQPLT GTVKKSPESLVKPVVPPLPCPQHVRIKNWGNGTTFQDTLHHKAKGAFTCKAKSCLGSIMT PKSLTRGPRDKPTPPDELLPQAIEFVNQYYGSFKEAKIEEHLARVEAVTKEIETTGTYQL TGDELIFATKQAWRNAPRCIGRIQWSNLQVFDARNCSTAREMFEHICRHLRYSTNNGNIR SAITVFPQRSDGKHDFRIWNAQFIRYAGYQMPDGSIRGDPANVEFTQLCIDLGWKPKYGR FDVVPLVLQADGRDPELFEIPPDLVLEVPMEHPKYEWFRELELKWYALPAVSNMLLEVGG LEFPGCPFNGWYMGTEIGVRDFCDVQRYNILEEVGRRMGLETHKLTSLWKDQAVVEINIA VLYSFQKQNVTIMDHHSAAESFMKYMQNEYRSRGGCPADWIWLVPPMSGSITPVFHQEML NYVLSPFYYYQVEAWRTHVWQDEKRRPRRREIQFKVLVKAVLFACVLMRKTMASRVRATI LFATETGKSEALASDLGALFSCAFNPKVLCMDDYRLSSLEEEQLLLVVTSTFGNGDCPGN GEKLKKSLFLLKELTNKFRYAVFGLGSSMYPQFCAFAHDIDQKLSQLGASQLAPTGEGDE LSGQEDAFRSWAVQTFKVACETFDVRGKQHIQIPKLYTSNVTWDPHHYRLVQDSQPLDLN KALGSMHAKNVFTMRLKSQQNLQSPKSSRTTLLVELSSEDSGSLNYLPGEHLGVFPGNQP ALVQGILQQVVDGPAPHQTVHLETLNESGGYWVSDKRLPSCSLSQALTYFLDITTPPTQL LLQKLAQLATEEAERQRLETLCQPSEYSRWKFTNSPTFLEVLEEFPSLRVSAAFLLSQLP TLKPRYYSISSSRDHTPTEVHLTVAVVTYRTRDGQGPLHHGVCSTWLSNLKPQDPVPCFV RSASGFHLPEDPSRPCILIGPGTGIAPFRSFWHQRLHDSEHKGLRGGRVTLVFGCRRPDE DHLYQEEMMEMARKGVLHEVHTAYSRLPGRPKVYVQDILRQQLASEVLRVLHEERGHLYV CGDVRMARDVACTLRQLVASKLSLSEEQVEDYFFQLKNQKRYHEDIFGAVFPYEMKKDRT AEQPGHLEISML NT seq 3459 nt NT seq  +upstreamnt  +downstreamnt atgcgcgaggggctgggcgcggcgtgcgaggccgccgggccccggctgtgccggctcctc cgcaggatcctccggccgaagcccgcctgccgcccgcgccgagccagtccggtgacacag gatgaccccaagtatcacagcctcagcaagcaccagaatgagtccctccagcccctcacg gggacggtcaagaagtctccagaatccctggtcaagccagttgtgcccccattgccctgc ccacagcacgtgaggatcaaaaactggggcaatgggacgactttccaagacacgctccac cacaaggccaaaggggctttcacttgcaaggccaaatcttgcctgggatccatcatgacc cccaaaagtttgaccagaggacccagggacaagcctactcctccggacgagcttctacct caagctatcgaatttgtgaaccagtattacggctccttcaaagaggcaaaaatagaggaa catctggccagggtggaagcggtgacaaaggagatagaaacaacaggaacctaccaactg acgggagatgagctcatctttgccaccaagcaggcctggcgcaacgccccccgctgcatc gggaggatccagtggtccaacctgcaggtcttcgatgcccggaactgttccactgcccgg gaaatgtttgagcacatctgcagacacctgcgttattccaccaacaacggcaacatcagg tcggccatcaccgtgttcccccagcggagcgatgggaagcacgacttccggatctggaac gctcagttcatccgatatgccggctaccagatgcccgatggctccatcagaggggaccct gccaacgtggagttcacccagctgtgcatcgacctgggctggaagcccaagtacggccgc ttcgacgtggtgcccctggtcctgcaggctgacggccgcgaccctgagctcttcgaaatc ccgcctgaccttgtgcttgaggtgcccatggaacatcccaagtacgagtggttccgggag ctggagctgaagtggtatgccctgcccgcagtgtccaatatgttgctcgaagtgggtggc cttgagttcccggggtgccccttcaatggctggtacatgggcacggagatcggggtccgg gacttctgtgacgtccagcgctacaacatcctggaggaagtgggcagaagaatgggtctg gaaacgcacaagctgacctcgctctggaaggaccaggctgttgtcgagatcaacattgct gtgctctatagtttccagaagcaaaacgtgaccattatggaccaccactcagctgcagag tccttcatgaagtacatgcagaacgagtaccggtcccgtgggggctgcccagccgactgg atctggctggtccctcccatgtctgggagcatcacccctgtgtttcaccaggagatgctc aactatgtcctgtcccctttctactactaccaggtggaggcctggagaacccacgtctgg caggacgagaagcggagacccaggagaagagagattcagttcaaagtcttggttaaagct gtgctctttgcctgtgtgctgatgcgcaagacgatggcctcccgagtcagagccacaatc ctctttgcgacagagacaggaaaatcagaagcgctggcctcggacctgggggccttgttc agctgtgccttcaaccctaaggttctctgcatggacgactacaggctgagcagcctggag gaggagcagctgctgctggtggtgaccagcacgtttgggaatggagactgccccggcaat ggagagaaactgaagaagtccctcttcctgctgaaagagctcaccaacaaattcaggtat gccgtgtttggcctcggctccagcatgtaccctcagttctgcgcctttgctcacgacatc gaccagaagctgtcccaactgggggcctctcagctcgcccccaccggggaaggggacgag ctcagcgggcaggaggacgccttccgcagctgggccgtgcaaactttcaaggtagcctgt gagacatttgatgtccgaggcaagcaacacattcagatccccaagctctacacctccaat gtgacctgggacccccaccactacaggctcgtgcaggactcacagcctttggacctcaac aaagccctcggcagcatgcatgccaagaacgtgttcaccatgaggctcaaatctcagcag aatctacagagtccgaaatccagccgcacgacgctcctggtggagctctccagtgaggac agcggcagcctgaactacctgcccggggagcacctcggcgttttcccaggcaaccagccg gccctggtccaaggcatcttgcagcaagtggtggacggccctgcgccccaccagacggtg cacctggagaccctgaacgagagcggcggctactgggtcagcgacaagaggctgccatcc tgctcactcagccaggccctcacctacttcctggacatcaccactcccccaacccagctg ctgctccaaaagctggcccagctggccacggaagaggccgagagacagaggctggagacc ctgtgccagccctcagagtacagcaggtggaagttcaccaacagccccacgttcctggag gtgctggaagagttcccgtccctgcgggtgtcggctgccttcctgctgtcccagctcccc actctgaagccccggtactactccatcagctcctcccgggaccacacccccacggaggtg cacctgaccgtggccgtggtcacctaccgcacccgagatggccagggtcccctgcaccat ggtgtctgcagcacatggctcagcaacttgaagccccaagacccagtgccgtgctttgtg cgaagtgccagcggcttccatctccccgaggacccctcccgaccttgcatcctcatcggg cccggcacaggcatcgcccccttccgcagtttctggcaccagcggctccatgactccgag cacaaagggctccgcggcggccgcgtgaccctggtgttcgggtgccgccgcccagacgag gaccacctgtatcaggaggagatgatggagatggcccggaagggcgtgctgcatgaggtg cacaccgcctattcccgcctgcctggcaggcccaaggtgtatgttcaagacatcctgcgg cagcagctggccagcgaggtgctccgtgtgctgcacgaggagcgaggccacctctacgtc tgtggggacgtgcgcatggcccgggacgtggcctgtaccctgaggcagctggtggcctcc aaactgagcctgagcgaggagcaggtggaggactatttcttccagctcaagaaccagaag cgctatcatgaagatatcttcggtgctgtatttccttatgagatgaaaaaggacaggaca gcggagcagccaggccacctggagatctcaatgctctga

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