Lemur catta (Ring-tailed lemur): 123620525
Help
Entry
123620525 CDS
T08326
Symbol
ERN1
Name
(RefSeq) serine/threonine-protein kinase/endoribonuclease IRE1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
lcat
Lemur catta (Ring-tailed lemur)
Pathway
lcat04140
Autophagy - animal
lcat04141
Protein processing in endoplasmic reticulum
lcat04210
Apoptosis
lcat04932
Non-alcoholic fatty liver disease
lcat05010
Alzheimer disease
lcat05012
Parkinson disease
lcat05014
Amyotrophic lateral sclerosis
lcat05016
Huntington disease
lcat05017
Spinocerebellar ataxia
lcat05022
Pathways of neurodegeneration - multiple diseases
lcat05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
lcat00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
123620525 (ERN1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
123620525 (ERN1)
09143 Cell growth and death
04210 Apoptosis
123620525 (ERN1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
123620525 (ERN1)
05012 Parkinson disease
123620525 (ERN1)
05014 Amyotrophic lateral sclerosis
123620525 (ERN1)
05016 Huntington disease
123620525 (ERN1)
05017 Spinocerebellar ataxia
123620525 (ERN1)
05022 Pathways of neurodegeneration - multiple diseases
123620525 (ERN1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
123620525 (ERN1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
123620525 (ERN1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
lcat01001
]
123620525 (ERN1)
Enzymes [BR:
lcat01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
123620525 (ERN1)
Protein kinases [BR:
lcat01001
]
Serine/threonine kinases: Other
IRE family
123620525 (ERN1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
Ribonuc_2-5A
PK_Tyr_Ser-Thr
PQQ_2
PQQ
Pkinase_fungal
Kdo
APH
Band_3_cyto
Motif
Other DBs
NCBI-GeneID:
123620525
NCBI-ProteinID:
XP_045381774
LinkDB
All DBs
Position
15:complement(44252892..44343721)
Genome browser
AA seq
975 aa
AA seq
DB search
MPARLLLLLLALLLPGSGIFGSTSTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTLKEDP
VLQVPTHVEEPAFLPDPNDGSLYTLGGKNNEGLTKLPFTIPELVQASPCRSTDGILYMGK
KQDIWYVIDLLTGEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNATYF
DYAASLPEDDMDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYVWQREGLRKV
MHINVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLTPTLYVGKYSTSLYASPSMV
HEGVAVVPRGSTLPLLEGPQTNGVTIGDKGECVITPSTDLKFDPGLKSKNKLNYLRNYWL
LIGHHETPLSASTKMLERFPNNLPKHRENVIPADSEKKSFEEVINLVDQASENAPTTVSQ
DVEEKPAHAPAKPEAPVDSMLKDMATIILSTFLLVGWVAFIITFPLSMHQQRQLQRQQFQ
KELEKIQLLHQQQLPFPPPGDATQDGEFLDTSGAYSESSGTSSPSTSPRASNHSLCSGSS
ASRAGTSPFLEQDDEDEETSVVMVGKISFCPKDVLGHGAEGTIVYRGMFDNRDVAVKRIL
PECFSFADREVQLLRESDEHPNVIRYFCTERDRQFQYIAIELCAATLQEYVEQKDFAHLG
LEPITLLQQTTSGLAHLHSLNIVHRDLKPHNILLSMPNAHGRIKAMISDFGLCKKLAVGR
HSFSRRSGVPGTEGWIAPEMLSEDCKDNPTYTVDIFSAGCVFYYVISEGSHPFGKSLQRQ
ANILLGAYSLDCFHPEKHEDVVARELIEKMIAMDPQKRPSAKHVLKHPFFWSLEKQLQFF
QDVSDRIEKEPLHGPIVKQLERGGRAVVKLDWRENITVPLQTDLRKFRTYKGGSVRDLLR
AMRNKKHHYRELPEEVRETLGSLPDDFVCYFTSRFPHLLSHTYRAMELCSHERLFQPYYS
QEPLEPQPPVTPDTH
NT seq
2928 nt
NT seq
+upstream
nt +downstream
nt
atgccggcccggctgctgctgctgctgctggcgctgttgctgcccggctctgggattttt
ggaagtaccagcacagtgacgcttcctgaaaccttattgtttgtgtcaaccctggatgga
agtttgcatgctgtcagcaagaggacaggctccatcaaatggactttaaaagaagatcca
gtcctgcaggtcccaactcatgtggaagagcctgccttcctcccagatcccaacgatggc
agcctatacacacttgggggcaagaataatgaaggtctgacaaaacttccatttaccatc
ccagagttggtgcaggcatcaccatgccgaagtacagacggaatcctctacatgggtaaa
aagcaggacatttggtatgttattgaccttctgactggggagaagcagcagactttgtca
tcggcctttgcagacagtctgtgcccatcaacctctcttctgtatcttgggcgaacagaa
tataccatcaccatgtacgacaccaaaacccgggagctccggtggaacgccacctacttt
gactatgcagcctcactgcccgaggacgacatggactataagatgtcccactttgtgtcc
aatggcgacgggctggtggtaaccgtggacagtgaatctggggacgtcctgtggatccaa
aactatgcctcccctgtggtggccttctatgtctggcagcgggagggtctgcggaaggtg
atgcacatcaacgtcgccgtggagaccctgcgctacctgaccttcatgtcgggggaggtg
gggcgcatcaccaagtggaagtacccgttccccaaggagacggaggccaagagcaagctg
acgcccaccctttacgttgggaaatactctaccagcctctatgcctccccctccatggta
cacgagggagttgctgtcgtgccccgcggcagcactctccctttgctggaaggcccccag
actaatggtgtcaccattggggacaaaggggagtgtgtgatcacacccagcaccgacctc
aagttcgaccctggactcaaaagcaagaacaagctcaactacttgaggaattactggctc
ctgataggacaccatgaaaccccactgtctgcgtctaccaagatgctggagagatttccc
aacaatctgcccaaacatcgggaaaacgtgattcccgctgattcagagaaaaagagcttt
gaggaagttatcaacctggtggaccaggcttcggaaaatgcacccaccaccgtgtctcag
gacgtggaagagaagcctgcccacgcccccgccaagcccgaggcccccgtggactccatg
ctcaaggacatggccaccatcatcctcagcaccttcctgctggtcggctgggtggccttc
atcatcaccttccccttgagcatgcatcaacagcggcagctccagcgccagcagttccag
aaggaactggagaaaatccagctcctgcaccagcagcagctgcccttccccccacctggg
gacgccactcaggacggcgagttcctggacacgtctggcgcgtactcggagagctcgggc
accagcagccccagcacgtctcccagagcctccaaccactcgctctgctccggcagctct
gcatccagggctggcaccagccccttcctggagcaggacgacgaggatgaggaaaccagc
gtggtgatggttgggaagatttcattctgtcctaaggacgtgctgggccatggagctgag
ggcacaatcgtgtaccggggcatgtttgacaaccgagacgtggctgtgaaaagaatcctc
cccgagtgcttcagcttcgcagaccgagaggtgcagctgctgcgagagtcggacgagcac
ccgaacgtgatccgctacttctgcacagagcgtgaccgccagttccagtacatcgccata
gagctgtgcgcggccaccctgcaagagtatgtggagcagaaggactttgcccacctcggc
ctggagcccatcaccttgctgcagcagaccacctcgggcctggcccacctccactccctc
aacatcgttcacagagacctgaagccccacaacatcctcctctctatgcccaacgcacac
ggcaggatcaaggccatgatctccgactttggcctctgcaagaagctggcggtgggcagg
cacagcttcagccgccgttctggggtgcctggcacggaaggctggattgctcccgagatg
ctgagtgaagactgcaaggacaaccctacctacacggtggacatcttctctgcaggctgc
gtcttctactatgtgatctctgagggcagccaccctttcggcaagtccctgcagcggcag
gccaacatcctcctgggcgcctacagcctcgactgcttccaccccgagaagcatgaagat
gttgttgcacgtgaactaatagagaaaatgatcgcaatggatccgcagaaacgcccctcg
gcgaagcacgttctgaaacatccgttcttctggagcctggagaagcagctccagttcttt
caggacgtgagcgaccggatagagaaggagccgctgcacggcccgatagtgaagcagctg
gagcgcggcggcagagccgtggtgaagctagactggcgggagaacatcaccgtccccctc
cagacagatctgcgtaaattcagaacctataagggcggctctgtcagggacctcctccgc
gccatgagaaataagaagcaccactaccgggagctccccgaggaggtgcgggagacgctg
ggctccctcccggacgacttcgtgtgctacttcacgtcgcgcttcccccacctcctctcg
cacacctaccgggccatggagctgtgcagccacgagagactcttccagccctactactcc
caggagcccctggaaccccagccccccgtgaccccagacacccactga
DBGET
integrated database retrieval system
