Lemur catta (Ring-tailed lemur): 123627225
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Entry
123627225 CDS
T08326
Symbol
PDHA2
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial isoform X1
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
lcat
Lemur catta (Ring-tailed lemur)
Pathway
lcat00010
Glycolysis / Gluconeogenesis
lcat00020
Citrate cycle (TCA cycle)
lcat00620
Pyruvate metabolism
lcat00785
Lipoic acid metabolism
lcat01100
Metabolic pathways
lcat01200
Carbon metabolism
lcat01210
2-Oxocarboxylic acid metabolism
lcat04066
HIF-1 signaling pathway
lcat04922
Glucagon signaling pathway
lcat05230
Central carbon metabolism in cancer
lcat05415
Diabetic cardiomyopathy
Module
lcat_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
lcat00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
123627225 (PDHA2)
00020 Citrate cycle (TCA cycle)
123627225 (PDHA2)
00620 Pyruvate metabolism
123627225 (PDHA2)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
123627225 (PDHA2)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
123627225 (PDHA2)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
123627225 (PDHA2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
123627225 (PDHA2)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
123627225 (PDHA2)
Enzymes [BR:
lcat01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
123627225 (PDHA2)
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Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
123627225
NCBI-ProteinID:
XP_045392633
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All DBs
Position
24:complement(10070743..10071915)
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AA seq
390 aa
AA seq
DB search
MRKMLAALLSRVLAAAPKPARPVPVASCTYSSDATFEIPKCDLYRLEEGPPGSAALARQD
GLRYYRAMVAVRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLEAAIAPSDHVITSYRA
HGVGYTRGLPVRAILAELTGRRGGCAKGKGGSMHMYARNFYGGNGIVGAQGPLGAGVALA
CKYSGGDRICLTLYGDGAANQGQVAEAFNMAALWKLPCVFVCENNRYGMGTAAERAAAST
DYYTRGGVIPGLRADGMDVLCVREAARFAAAHCRAGRGPIVLELRTYRYHGHSMSDPGVS
YRGREEVQEVRSKSDPVMLLTDRLVGSGLATAEELREIDAGVRREVDEAAEFATSDPEPD
LGDLAHHIYSSDPAFEVRGTHPWIKFKSIS
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagatgctggctgctctcctctcccgcgtgttggccgcggccccgaagccggct
cgcccggtgccggtggcgtcctgcacctattccagcgacgccacgttcgagattccgaag
tgcgacctgtaccggctggaagagggcccgccggggagcgcggcgctggcgcggcaggac
gggctgcggtactaccgcgcgatggtggcggtgcggcgcatggagctgaaggcggaccag
ctgtacaagcagaagttcatccgcggcttctgccacctgtgcgacggccaggaggcctgc
tgcgtggggctggaggccgccatcgcgccctcggaccacgtgatcacgtcgtaccgcgcg
cacggcgtgggctacacccgcgggctgcccgtgcgcgccatcctggcggagctgacgggc
cgccggggcggctgcgccaagggcaagggcggctccatgcacatgtacgcccggaacttc
tacggcggcaacggcatcgtcggcgcgcagggcccgctcggggccggcgtcgccctggcc
tgcaagtacagcggcggcgaccggatctgcctgaccctgtacggcgacggcgctgccaac
cagggccaggtggccgaggccttcaacatggccgcgctgtggaagctgccctgcgtgttc
gtgtgcgagaacaaccgctacgggatgggcacggcggccgagcgcgcggccgccagcacc
gactactacacgaggggcggcgtcatccccgggctgcgggccgacggcatggacgtgctg
tgcgtgcgggaggccgcccgcttcgccgccgcccactgccgcgccggccggggccccatc
gtgctggagctgcggacctaccgctaccacggccacagcatgagcgaccccggcgtcagc
taccggggacgggaggaagtccaggaggtgcgcagcaagagcgaccccgtcatgctgctc
acggacaggctggtgggcagcgggctggccacggccgaggagctgcgggagatcgacgcc
ggcgtgaggagggaggtggacgaggcggccgagttcgccaccagcgaccccgagccggac
ctgggggacttggcccatcacatctacagcagcgacccggctttcgaagtgcgcggcacg
cacccgtggatcaagttcaagtccatcagttaa
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