KEGG   Lemur catta (Ring-tailed lemur): 123639374
Entry
123639374         CDS       T08326                                 
Symbol
IGF1
Name
(RefSeq) insulin-like growth factor I isoform X1
  KO
K05459  insulin-like growth factor 1
Organism
lcat  Lemur catta (Ring-tailed lemur)
Pathway
lcat01521  EGFR tyrosine kinase inhibitor resistance
lcat01522  Endocrine resistance
lcat04010  MAPK signaling pathway
lcat04014  Ras signaling pathway
lcat04015  Rap1 signaling pathway
lcat04066  HIF-1 signaling pathway
lcat04068  FoxO signaling pathway
lcat04114  Oocyte meiosis
lcat04115  p53 signaling pathway
lcat04150  mTOR signaling pathway
lcat04151  PI3K-Akt signaling pathway
lcat04152  AMPK signaling pathway
lcat04211  Longevity regulating pathway
lcat04213  Longevity regulating pathway - multiple species
lcat04510  Focal adhesion
lcat04550  Signaling pathways regulating pluripotency of stem cells
lcat04730  Long-term depression
lcat04750  Inflammatory mediator regulation of TRP channels
lcat04913  Ovarian steroidogenesis
lcat04914  Progesterone-mediated oocyte maturation
lcat04935  Growth hormone synthesis, secretion and action
lcat04960  Aldosterone-regulated sodium reabsorption
lcat05200  Pathways in cancer
lcat05202  Transcriptional misregulation in cancer
lcat05205  Proteoglycans in cancer
lcat05214  Glioma
lcat05215  Prostate cancer
lcat05218  Melanoma
lcat05224  Breast cancer
lcat05410  Hypertrophic cardiomyopathy
lcat05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:lcat00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    123639374 (IGF1)
   04014 Ras signaling pathway
    123639374 (IGF1)
   04015 Rap1 signaling pathway
    123639374 (IGF1)
   04066 HIF-1 signaling pathway
    123639374 (IGF1)
   04068 FoxO signaling pathway
    123639374 (IGF1)
   04151 PI3K-Akt signaling pathway
    123639374 (IGF1)
   04152 AMPK signaling pathway
    123639374 (IGF1)
   04150 mTOR signaling pathway
    123639374 (IGF1)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    123639374 (IGF1)
   04115 p53 signaling pathway
    123639374 (IGF1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    123639374 (IGF1)
   04550 Signaling pathways regulating pluripotency of stem cells
    123639374 (IGF1)
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    123639374 (IGF1)
   04914 Progesterone-mediated oocyte maturation
    123639374 (IGF1)
   04935 Growth hormone synthesis, secretion and action
    123639374 (IGF1)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    123639374 (IGF1)
  09156 Nervous system
   04730 Long-term depression
    123639374 (IGF1)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    123639374 (IGF1)
  09149 Aging
   04211 Longevity regulating pathway
    123639374 (IGF1)
   04213 Longevity regulating pathway - multiple species
    123639374 (IGF1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    123639374 (IGF1)
   05202 Transcriptional misregulation in cancer
    123639374 (IGF1)
   05205 Proteoglycans in cancer
    123639374 (IGF1)
  09162 Cancer: specific types
   05214 Glioma
    123639374 (IGF1)
   05218 Melanoma
    123639374 (IGF1)
   05215 Prostate cancer
    123639374 (IGF1)
   05224 Breast cancer
    123639374 (IGF1)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    123639374 (IGF1)
   05414 Dilated cardiomyopathy
    123639374 (IGF1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    123639374 (IGF1)
   01522 Endocrine resistance
    123639374 (IGF1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:lcat04052]
    123639374 (IGF1)
Cytokines and neuropeptides [BR:lcat04052]
 Cytokines
  Growth factors (RTK binding)
   123639374 (IGF1)
SSDB
Motif
Pfam: Insulin
Other DBs
NCBI-GeneID: 123639374
NCBI-ProteinID: XP_045409050
LinkDB
Position
6:18237860..18315064
AA seq 153 aa
MGKISSLPTQLFKCCFCDFFKVKMHITSSSHLLYLALCLLTFTSSAAAGPETLCGAELVD
ALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSARS
VRAQRHTDMPKTQKEVHLKNASRGSAGNKNYRM
NT seq 462 nt   +upstreamnt  +downstreamnt
atggggaaaatcagcagtcttccaacccaattatttaagtgctgcttttgtgatttcttt
aaggtaaagatgcacatcacatcctcctcgcatctcctctacctggccctgtgcttactc
accttcaccagctccgccgcagctggacccgagacgctctgcggggctgagctggtggat
gctcttcagttcgtgtgtggagacaggggcttttatttcaacaagcccacagggtacggc
tccagcagtcggagggcgcctcagacaggcatcgtggatgagtgctgcttccggagctgt
gatctgaggaggctggagatgtactgtgcacccctcaagcctgccaagtcagcccgttct
gtccgtgcccagcgccacaccgacatgcccaagactcagaaggaagtacatttgaagaac
gcaagtagagggagtgcaggaaacaagaactacagaatgtag

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