KEGG T02913: 102361445

Latimeria chalumnae (coelacanth): 102361445

Entry

102361445         CDS       T02913

Symbol

HSD17B8

Name

(RefSeq) hydroxysteroid 17-beta dehydrogenase 8

K13370

17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) / 3-oxoacyl-[acyl-carrier protein] reductase alpha subunit [EC:1.1.1.62 1.1.1.239]

Organism

lcm Latimeria chalumnae (coelacanth)

Pathway

lcm00061

Fatty acid biosynthesis

lcm00140

Steroid hormone biosynthesis

lcm01100

Metabolic pathways

lcm01212

Fatty acid metabolism

Module

lcm_M00976

C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone

Brite

KEGG Orthology (KO) [BR:lcm00001]
09100 Metabolism
  09103 Lipid metabolism
   00061 Fatty acid biosynthesis
    102361445 (HSD17B8)
   00140 Steroid hormone biosynthesis
    102361445 (HSD17B8)
Enzymes [BR:lcm01000]
1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.62  17beta-estradiol 17-dehydrogenase
     102361445 (HSD17B8)
    1.1.1.239  3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
     102361445 (HSD17B8)

SSDB

Motif

Pfam:

adh_short_C2 adh_short KR 3Beta_HSD Epimerase Polysacc_synt_2 GDP_Man_Dehyd

Other DBs

NCBI-GeneID:

102361445

NCBI-ProteinID:

XP_014346905

Ensembl:

ENSLACG00000012715

LinkDB

Position

AA seq 255 aa
MAAPLRLVSRLALVTGGGSGIGHAVCQKLAREGAAVAVVDVIEAAAHETMRTLPCDHPEQ
QHEAFCADISSSEGVKQLLEGVQMKYSRPACIVVNCAGIIMDEFLLKMEEEDFDRVLAVN
LKGTFLITRGFSNALIASGAKKGSIINLGSIVGKVGNLGQANYAASKAGVEGLTKTAAKE
LARFGIRCNTVAPGFIATPMTDKVPKKVLEKIEKVIPLGRLGDPEDVAEACAFLASDDSS
YITGTSLEITGGLFL

NT seq 768 nt +upstreamnt +downstreamnt
atggcggcgcccttgagattggtgtccaggctggctctggttacaggcgggggcagcgga
atcgggcatgcggtgtgccagaagctcgccagggaaggcgctgcagtggccgttgttgat
gtcattgaggcagcggcccatgaaacgatgagaacgttgccatgtgaccacccagaacag
caacatgaggccttctgcgcggatatctcctcctcagaaggagtcaagcaactcctggag
ggagtacagatgaagtattcccgcccagcgtgcatcgtcgtgaactgcgccgggattatc
atggatgagtttcttctcaagatggaggaggaggactttgaccgggtcttagccgttaac
ttaaagggtacgttcttgatcactcgtggcttctccaatgctctgattgctagtggcgcc
aagaagggttccatcatcaacctgggcagcatcgtgggcaaggtggggaacttgggacaa
gccaactacgcagcctctaaagccggagtggagggactcaccaaaaccgcggcgaaggaa
ttagccaggttcgggatccggtgtaatactgtcgctccagggtttatagccaccccgatg
acagataaggtccctaagaaagtacttgagaagattgaaaaggtgattccattgggacga
ctgggagacccagaagatgtggctgaggcctgcgccttccttgcctccgacgacagcagt
tacatcacaggcaccagccttgagattacaggtggacttttcctgtag

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