Larimichthys crocea (large yellow croaker): 104939728
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Entry
104939728 CDS
T04659
Symbol
gclc
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
lco
Larimichthys crocea (large yellow croaker)
Pathway
lco00270
Cysteine and methionine metabolism
lco00480
Glutathione metabolism
lco01100
Metabolic pathways
lco01240
Biosynthesis of cofactors
lco04216
Ferroptosis
Module
lco_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
lco00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
104939728 (gclc)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
104939728 (gclc)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
104939728 (gclc)
Enzymes [BR:
lco01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
104939728 (gclc)
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Motif
Pfam:
GCS
GCS2
Motif
Other DBs
NCBI-GeneID:
104939728
NCBI-ProteinID:
XP_010754585
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Position
III:14583564..14592362
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AA seq
633 aa
AA seq
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MGLLTQGSPLNWEETKKYADHIRKHGIIQFLNIYNKVKERQKDVLKWGDEVEYMLVELDD
KNEKVRIVLNGREILETLQEQGENINPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
EGNMGKRRREASSVLNQNETLCTITAFPRLGCPGFTKPEYRPTPVEKGVSKSLFFPDEAI
NHHPRFSTLTRNIRHRRGEKVAINVPIFKDKCTPSPFVEEFPEDDGEAARAALPDHIYMD
AMGFGMGNCCLQVTFQACSIDEARYLYDQLATFCPIVMALSAASPFYRGYVSDIDCRWGV
ISASVDDRTQEERGLKPLQNDKYRIFKSRYDSIDSYLSSCGEKYNDIDLTIDEEIYKQLL
NAGIDKLLAQHIAHLFIRDPLSVFEEKIHLDDENESDHFENLQSTNWQTMRFKPPPPNSD
IGWRVEFRPMEVQLTDFENAAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRNAV
QEGMFYFRKDIYKGCNPVFDGTASAHNGLETDCADGANEEYTLMSIDTIINGKEGVFQGL
IPILNCYLENMEVDVDTRCTILNYLKLIKKRASGELMTMAKWMREFVAKHPQYKQDSVLT
DKINYDLFKKCDRIAKGEEQCPELIGNPVNKFK
NT seq
1902 nt
NT seq
+upstream
nt +downstream
nt
atgggtttactgacacaggggtctccactgaactgggaagaaaccaagaaatatgccgac
cacatcaggaaacacggcatcatccagtttctaaacatctacaacaaggtgaaggagcgt
cagaaagatgtgctgaagtggggcgatgaggtcgagtacatgttggtggagttggatgac
aagaacgaaaaggttcgaatcgttctgaacggcagagaaattttggaaactctgcaagag
cagggtgaaaacataaaccccaatcatcccacactgtggagaccagagtatggcagctac
atgatcgaaggaactccaggtcagccgtatggcgggaccatgtcggagttcaacactgtg
gagggcaacatggggaagagacgacgagaggcctcgtctgtcctgaaccagaacgaaacc
ctctgcaccatcacagcgtttccaaggttaggttgccctggttttactaaaccagagtac
cggccgacccctgttgaaaagggagtgtccaagtcactgtttttcccagatgaagccatc
aaccaccacccaagattcagcacccttactagaaacatacgtcacagaagaggagagaaa
gtcgctattaatgtaccaatcttcaaagacaagtgcactccatctccgtttgtggaagag
ttccctgaggatgacggtgaagcggcgagggcggctctgcctgatcacatctacatggac
gccatgggctttggcatggggaactgctgtctgcaggtgacattccaggcttgtagcatt
gatgaggcaagatacctttatgaccaactagcaacattctgccctatagtgatggcgttg
agtgcggcctcacccttctacagaggctatgtgtcagatattgactgtcgttggggcgtt
atctctgcctctgtggatgacaggacacaggaggaacgtgggctcaagccgttgcaaaac
gacaaatacaggatcttcaagtcaagatatgattcgattgacagctacctgtcgagctgc
ggtgagaagtacaacgacatagatctgacgatagacgaggagatctacaagcagctgctc
aatgcaggtatcgacaagctgctggcccagcacatagcacacctcttcatccgagatcca
ctctctgtctttgaggagaaaattcacttggatgatgaaaacgagtccgaccactttgag
aacttgcagtcgacaaactggcagacgatgaggtttaaacctccacctccaaactctgat
atcggctggagagttgaattccgccccatggaggtgcagctaactgactttgaaaacgct
gcatacgtggtctttgtcgtgctgctcaccagagtaatcttgtcctataaactggacttt
ctgatccctttgtcaaaggttgatgaaaacatgaaggtggcacaaaagagaaacgctgtc
caggagggcatgttttacttcagaaaggacatctacaaaggctgtaatccggtctttgat
ggcactgcttctgctcacaatggcctggagaccgattgtgcagatggtgctaacgaggag
tacacgctgatgagcattgacaccatcatcaatggaaaggagggagtattccaagggctt
atcccaatccttaactgttatctggaaaacatggaagttgatgtggacaccaggtgcacc
attttgaattatctgaagctcatcaagaaacgtgcctcaggtgaactgatgaccatggcc
aagtggatgagggagtttgttgcaaagcacccgcagtataagcaggacagcgtcctaact
gacaagatcaactacgacctgttcaaaaagtgcgacaggattgcaaaaggcgaagagcag
tgcccggagctcattggaaacccggtcaacaaattcaaatga
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