Leclercia sp. W17: DVA44_06825
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Entry
DVA44_06825 CDS
T05987
Name
(GenBank) bifunctional tetrahydrofolate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
lee
Leclercia sp. W17
Pathway
lee00790
Folate biosynthesis
lee01100
Metabolic pathways
lee01240
Biosynthesis of cofactors
Module
lee_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
lee00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
DVA44_06825
Enzymes [BR:
lee01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
DVA44_06825
6.3.2.17 tetrahydrofolate synthase
DVA44_06825
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
AXF63861
UniProt:
A0A345C7V6
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Position
1386521..1387789
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AA seq
422 aa
AA seq
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MENTTLPQATSPLAAWLSYLENLHSKAIDMGLERVSQVAARLDVLKPAPFVFTVAGTNGK
GTTCRTLEAMLMAAGYKVGVYSSPHLVRYTERVRVQNTELAESAHTASFAEIEAARGDIS
LTYFEYGTLSALWLFKQAQLDVVILEVGLGGRLDATNIVDPDVAVITSIALDHTDWLGPD
RESIGREKAGIFRPGKPAIVGEPDMPHTIADVAQEKGALLQRRDVDWRYSVTESGWRFED
AAGALDNLPLPQVPQPNAATALAALRASGLAVEEQAMRDGIQHAILPGRFQIVSESPRLI
LDVAHNPHAAAYLAGRLKSLPKTGRVLAVIGMLHDKDIGGTLACMESVVDSWYCAPLEGP
RGATAEQLMAHLGAGQRFDSVAQAWRAAMADARPEDTVLVCGSFHTVAHVMDVMDTGRTG
GK
NT seq
1269 nt
NT seq
+upstream
nt +downstream
nt
atggaaaatactactcttccccaagccacgtcgcctctggccgcgtggctttcttatctg
gaaaacctgcacagtaaagccatcgacatgggacttgagcgcgtcagccaggtcgcggcg
cgccttgatgttctgaaaccggctccctttgtcttcaccgtggcgggtaccaacggcaaa
ggcaccacctgccgcaccctggaagcgatgctgatggcggcgggctacaaagtaggggtc
tacagctcgccccatctggtgcgctataccgagcgcgtgcgggtgcagaatacagaatta
gccgaatccgcgcacaccgcctcgtttgcagagatcgaagccgcgcgcggcgatatttcg
ctgacctattttgaatatggcactttgtcagcgctgtggctctttaagcaggcgcagctg
gacgtggtgatccttgaggtcgggttaggcgggcgtctggatgccacgaatattgtcgac
ccggatgtggcggtaatcaccagcatcgcgctggatcatactgactggctggggcccgat
cgcgagagcattggccgtgaaaaagccggtattttccgcccgggcaaaccggctatcgtc
ggcgaacccgatatgccgcacaccattgctgacgtggcgcaggagaaaggggcgctgttg
cagcgccgtgatgtcgactggcgctacagcgtgacggaaagcggctggcgctttgaagat
gcagcgggcgcgctggataacctgccgctgccccaggtaccgcagccaaatgccgccacg
gcgctggccgcactgcgcgccagtggtctggcggtagaggagcaggcgatgcgcgacggc
attcagcatgcgattctgccggggcgtttccagatagtcagcgaatcaccgcgtctgatt
ctggatgtggcgcataacccccatgccgcggcgtatctcgcaggacgtctcaaatcgttg
ccaaaaaccgggcgtgtgctggcggttatcggtatgcttcatgataaagatattggcggc
acgctggcctgcatggagagtgtggtcgatagctggtattgtgcccctctggaaggccca
cgcggggcgactgccgaacagttgatggcgcatctcggcgcagggcagcgctttgatagc
gtggcgcaggcctggcgggcggcgatggccgatgccagaccagaagataccgtgctggtg
tgtggttcgttccacacggtggcacatgtcatggacgtaatggatacggggagaaccggt
ggcaagtaa
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