Lelliottia sp. WB101: DAI21_04970
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Entry
DAI21_04970 CDS
T05398
Symbol
metL
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase II
KO
K12525
bifunctional aspartokinase / homoserine dehydrogenase 2 [EC:
2.7.2.4
1.1.1.3
]
Organism
lew
Lelliottia sp. WB101
Pathway
lew00260
Glycine, serine and threonine metabolism
lew00261
Monobactam biosynthesis
lew00270
Cysteine and methionine metabolism
lew00300
Lysine biosynthesis
lew01100
Metabolic pathways
lew01110
Biosynthesis of secondary metabolites
lew01120
Microbial metabolism in diverse environments
lew01230
Biosynthesis of amino acids
Module
lew_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
lew_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
lew_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
lew00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
DAI21_04970 (metL)
00270 Cysteine and methionine metabolism
DAI21_04970 (metL)
00300 Lysine biosynthesis
DAI21_04970 (metL)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
DAI21_04970 (metL)
Enzymes [BR:
lew01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
DAI21_04970 (metL)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
DAI21_04970 (metL)
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GFIT
Motif
Pfam:
AA_kinase
Homoserine_dh
NAD_binding_3
Motif
Other DBs
NCBI-ProteinID:
AVY97082
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Position
1055833..1058265
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AA seq
810 aa
AA seq
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MSVIAQAGAKGRQLHKFGGSSLADVKCYLRVAGIMAEYSMPGDMMVVSAAGSTTNQLISW
LKLSQTDRLSAHQVQQTLRRYQSDLIVGLLPADAADSLISAFVHDLERLAGLLDSGVTEA
VYAEVVGHGEVWSARLMAAVLEQQGLEAAWLDARDFLRAERAAQPQVDEGLSYPLLQQLL
VQHPGKRIVVTGFISRSNAGETVLLGRNGSDYSATQIGALAGASRVTIWSDVAGVYSADP
RKVKDACLLPLLRLDEASELARLAAPVLHARTLQPVSGSDIDLQLRCSYTPDKGSTRIER
VLASGTGARIVTSHDDICLIEFQVPAGQDFKLAHKDIDLILKRAQVRPLAVGVHNDRQLL
QFCYTAEVADSALKILDEAGLPGELRLRQGLALVAMVGAGVTRNPLHCHRFWQQLKGQPV
EFTWQSEEGISLVAVLRKGPTESLIQGLHTTLFRAEKRIGLVLFGKGNIGSRWLELFARE
QTTLSARTGFEFVLAGVVDSRRSLLNYDGLDASRALAFFNDEAVEQDEESLFLWMRAHPY
DDLVVLDVTASEQLADQYLDFASHGFHVISANKLAGASSTDKYRQIHDAFEKTGRHWLYN
ATVGAGLPVNHTVRDLIDSGDSILAISGIFSGTLSWLFLQFDGTVPFTDLVDQAWQQGLT
EPDPRVDLAGKDVMRKLVILAREAGYDIEPGQVRVESLVPAGCEEGSVDHFFENGEELNE
QMVSRLEAAREMGLVLRYVARFDANGKARVGVEAVRPEHPLAALLPCDNVFAIESRWYRD
NPLVIRGPGAGRDVTAGAIQSDINRLAQLL
NT seq
2433 nt
NT seq
+upstream
nt +downstream
nt
atgagtgtgatagcgcaggcaggggcgaagggtcgccagctgcacaagtttggtggtagt
agtcttgctgatgtgaaatgttacctgcgtgtcgcagggatcatggcggagtattcgatg
ccgggcgacatgatggttgtctcggcggcaggcagcactaccaaccagttgattagctgg
ctgaaattaagccagaccgatcgcctttctgcgcatcaggttcaacaaacgttacgccgc
tatcagagcgatctgatcgtcggcctgctgcctgcggacgcggcagacagcctcatcagc
gcatttgttcacgatctggagcgtctggccggattactggacagcggcgtgaccgaagcg
gtttacgctgaagtggtcggccacggtgaagtctggtctgcgcgcctgatggcggcagtc
ctggagcagcaagggctggaggccgcgtggctggacgcgcgcgatttcctgcgcgctgag
cgtgcggcgcaaccgcaggtcgacgagggcctctcttatcctctgctgcaacagctgctg
gtgcagcatccgggcaaacgcatcgtcgtgacgggctttatcagccgcagcaacgcgggc
gaaaccgtgcttctgggccgtaacggctcggactactcggcaacgcaaatcggtgcgctg
gcgggggcgtctcgcgtcactatctggagcgatgtggccggggtgtatagcgccgatccg
cgcaaagtaaaagatgcctgtctgctgccgctgctgcgtctggacgaagccagtgagctg
gcgcgtctggcagcaccggtcctgcacgcacgtaccttacagcctgtttcgggcagcgat
atcgacctgcagctgcgctgtagttacaccccagataaaggttcgacccgcatcgaacgc
gtactggcctcgggcacaggcgcgcgcatcgtgaccagtcacgatgatatttgcctgatc
gaattccaggtgcctgccggacaagatttcaaactggcacacaaagatatcgacctgatc
ctcaagcgcgcccaggtgcgccctctggccgttggcgtgcacaatgaccgccagctgctg
cagttctgctacaccgccgaagtggctgacagcgcgctgaaaattcttgatgaagccgga
ttaccgggcgaacttcgcctgcgtcaggggctggcgctggtcgcgatggtcggcgcgggt
gtcacccgtaacccgctccattgccaccgtttctggcaacagctgaaaggccagccggtg
gagttcacctggcagtcggaagagggcatcagcctggtcgccgtgctgcgtaaaggccca
accgagagcctgattcaggggctgcacaccaccctgttccgcgcggaaaaacgtatcggc
ctggtgctgttcgggaagggaaacatcggttcccgctggctggagctgtttgcccgcgag
caaacgacgctctctgcacgcaccggttttgaatttgtattagcaggcgtggtggacagc
cgccgcagcctgctgaactacgacgggctggacgccagccgcgcgctcgcatttttcaac
gatgaagcggtcgagcaggacgaagagtccctgttcctgtggatgcgcgcgcacccgtac
gacgatctggtcgtgctggacgtcactgccagcgagcagctggccgatcagtacctcgat
tttgccagccacggtttccacgttatcagcgcgaacaaactggccggcgcaagcagcacc
gataaataccgccaaatccacgacgcgtttgaaaaaaccggccgtcactggctatataac
gccaccgtgggtgccggtctgccggtgaaccacaccgtgcgcgacctgatcgacagcggt
gacagcattctggcaatcagcggtatcttctccggtaccctctcctggctgttcctgcag
tttgacggcaccgttccgtttacggacctggtggaccaggcgtggcagcaggggctgacg
gagccggacccgcgcgtggatctcgccggaaaagacgtgatgcgcaagctggtcattctg
gcgcgcgaagcgggttacgacattgagccaggccaggtgcgcgtggagtcgctggttccg
gccggttgcgaagaggggtcagtcgatcacttcttcgagaacggtgaggagctgaacgaa
cagatggtgtcacgcctggaagcggcacgcgaaatggggctggttctgcgctatgtggcc
cgttttgacgctaacggtaaagcccgcgtgggtgttgaggccgttcgccctgagcatcct
ctggcggcgttgctgccgtgcgataacgtcttcgccattgaaagccgttggtaccgtgat
aacccgctggtgattcgtgggccaggtgcggggcgcgacgtcaccgccggggcgattcag
tcagacattaatcgcctggcgcagctgctgtag
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