Leishmania infantum: LINJ_18_1360
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Entry
LINJ_18_1360 CDS
T01112
Name
(RefSeq) putative pyruvate dehydrogenase E1 component alpha subunit
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
lif
Leishmania infantum
Pathway
lif00010
Glycolysis / Gluconeogenesis
lif00020
Citrate cycle (TCA cycle)
lif00620
Pyruvate metabolism
lif00785
Lipoic acid metabolism
lif01100
Metabolic pathways
lif01110
Biosynthesis of secondary metabolites
lif01200
Carbon metabolism
lif01210
2-Oxocarboxylic acid metabolism
Module
lif_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
lif00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
LINJ_18_1360
00020 Citrate cycle (TCA cycle)
LINJ_18_1360
00620 Pyruvate metabolism
LINJ_18_1360
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
LINJ_18_1360
Enzymes [BR:
lif01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
LINJ_18_1360
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GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
SCD
Motif
Other DBs
NCBI-GeneID:
5068359
NCBI-ProteinID:
XP_001464949
UniProt:
A4HY08
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Position
18:588489..589625
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AA seq
378 aa
AA seq
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MFKCATRCLLDTKTVPLKPQRPFKLHTAGRTDMAPLPTQAAYDAEQLKKSLALMFRIRRM
ESLCDQSYKLKKIRGFCHLYIGQEAIPAGMENVLTFEDPIVTGYRDHGWYISRGGKPEDV
FAEMFGRQGGCSKGKGGSMHMYKVGNGFYGGNGIVGAQVSIGAGLAWRFAMENRDSPKHV
AVTFYGDGAANQGQIYESMNIAALQRLPVIFAVENNHFGMGTSAARGSYQAEFYRRGDYI
PGIKVDGMDVLAVQEGTRYARDHCMSGKGPIVMELDCYRYMGHSMSDPDNQYRTKSDIQH
VKQERDCIRKMREFMATEGIMTEDEMSKMEKDVKKEVDQDLQKAQKQPMTKLDELFTDIY
VGEQYEHRTCQGTVYHKP
NT seq
1137 nt
NT seq
+upstream
nt +downstream
nt
atgttcaagtgcgcgactcgctgccttctggacaccaagacggtgccgctgaagccgcag
cgcccattcaagctacacacggctggccgcaccgacatggcaccacttccgacgcaggcg
gcgtacgacgcagagcagctgaagaagagtcttgccctgatgttccgcatccgccgcatg
gagtctctgtgcgatcagtcctacaagctaaagaagattcgcggcttctgccacctctac
atcgggcaggaggccattccggctggcatggagaacgttctgaccttcgaggaccccatc
gtcactggctaccgcgatcacggctggtacatctctcgcggtggcaagcccgaggatgtc
ttcgctgaaatgttcggccgtcagggcggctgcagcaagggcaagggtggctcgatgcac
atgtacaaggtgggtaacggcttctacggcggtaatggcatcgtgggtgcgcaggtctcg
atcggcgctggccttgcctggcgcttcgcgatggagaaccgcgacagcccgaagcacgtt
gcggtcaccttctacggcgacggtgctgccaaccagggccagatctacgagtccatgaac
attgccgctctgcagcgcctccccgtcatcttcgcagtggagaacaaccacttcggtatg
ggcactagcgccgctcgcggctcctatcaggcggagttttaccgccgtggtgactacatc
cctggtatcaaggtcgatggcatggacgtgctcgcggtgcaggagggcacccgctacgca
cgcgaccactgcatgtcgggcaagggcccgattgtgatggagctggactgctaccgctac
atgggtcatagcatgtcggaccccgacaaccagtaccgcaccaagagcgacatccagcac
gtgaagcaggagcgtgactgcattcgcaagatgcgcgagttcatggcgaccgagggcatc
atgaccgaggacgagatgagcaagatggagaaagacgtgaagaaggaggtggaccaggac
ctgcagaaggcccagaaacaacctatgacaaagttggatgagctcttcacggacatctac
gtgggtgagcagtacgagcaccgcacctgccagggtaccgtgtaccacaagccctaa
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