Lactococcus lactis subsp. lactis KLDS 4.0325: P620_06270
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Entry
P620_06270 CDS
T02882
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
lld
Lactococcus lactis subsp. lactis KLDS 4.0325
Pathway
lld00790
Folate biosynthesis
lld01100
Metabolic pathways
lld01240
Biosynthesis of cofactors
Module
lld_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
lld00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
P620_06270
Enzymes [BR:
lld01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
P620_06270
6.3.2.17 tetrahydrofolate synthase
P620_06270
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
AGY44226
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Position
1171471..1172754
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AA seq
427 aa
AA seq
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MSIEEALEWIHSRLKFNIRPGLSRVSALLELLGHPEESLSMIHVAGTNGKGSTVAFTHSI
FMQAGLKVASFTSPFITTFGERMSINALPIADDKLIYYVEMIQPLVAELDKDAELTGITE
FEIITAMAFKYFSDEQVDLAVIEVGLGGLLDSTNVIKPVVSGITTIGLDHIDILGSTIEE
IAAQKAGIIKPGIPVVVGNIELKALRVIWEVARKNTARVYQFPYDYRTEVEEHEHFNFFS
GQEAILDIEKSLVGLHQIENAGMAIELSLVYASKVGIELTEDVIRSGIREAFWPARMEKL
GEKPLILLDGAHNVHAMNRLLENLSSEFPDKKITIIFSAITTKDISQMIKMLQTVKNSHL
ILTTFDYPKALNLGDFQRLEEEGVELAPSWELALVRAQKNLAEDDLLLVTGSLYFSSQVR
EFLKKEK
NT seq
1284 nt
NT seq
+upstream
nt +downstream
nt
atgtctatagaagaagcattggaatggatacattcacgtttaaaatttaatattcgccca
ggcctaagtcgtgtttcggcccttttagaattgcttggtcatccagaagagtctttgtca
atgattcacgttgctggaacaaatggaaaaggctccacagtcgctttcacacactcaatc
tttatgcaggcaggtctgaaggttgcttctttcacaagtcctttcatcaccacttttggt
gagcggatgtcgattaatgcactcccgattgctgatgataaattaatttattatgtagaa
atgatccaaccacttgttgctgaacttgataaagatgctgaactgactggaattaccgaa
tttgaaattatcacggcaatggcttttaaatatttctctgatgagcaggttgatttagcg
gttattgaagttggtttaggtggacttcttgattcaacaaatgtgattaaacctgttgtt
tctggaattacaacaattggtttagatcatattgatattcttggttcgaccattgaagaa
atcgcagctcaaaaggctggaattattaaaccaggaattccagtagttgttggaaatatt
gaattaaaagcacttcgggttatatgggaagtggctagaaaaaatacagcgcgtgtttat
caatttccatatgattatcgtacggaagtggaagaacacgaacattttaatttcttttct
ggtcaagaagcaatattggatattgaaaaatctttagttggcttacatcaaatagaaaat
gctggtatggctattgaactttctctggtttatgcaagtaaggttgggattgaattgact
gaggatgtgattcgctctggaattcgtgaggctttttggccagctcgtatggaaaaattg
ggtgaaaaaccactcattttactggatggtgctcataatgttcatgcgatgaatcgtttg
cttgaaaatcttagctctgagtttccagataaaaaaattacaatcattttttcagccatt
accacaaaagatattagtcaaatgataaaaatgcttcaaactgtgaaaaattcgcatctg
attttgacaacttttgattatccgaaagctttgaatttgggagattttcaaagattggaa
gaagaaggggttgaattggctccaagttgggaattagctttagttcgtgcgcaaaaaaat
ttagctgaagatgatttgttattagttacaggctctctctatttctcatctcaagttcgt
gagtttttgaaaaaagagaagtaa
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