Lutra lutra (Eurasian river otter): 125086988
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Entry
125086988 CDS
T08100
Name
(RefSeq) serine/threonine-protein kinase/endoribonuclease IRE1 isoform X1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
llv
Lutra lutra (Eurasian river otter)
Pathway
llv04140
Autophagy - animal
llv04141
Protein processing in endoplasmic reticulum
llv04210
Apoptosis
llv04932
Non-alcoholic fatty liver disease
llv05010
Alzheimer disease
llv05012
Parkinson disease
llv05014
Amyotrophic lateral sclerosis
llv05016
Huntington disease
llv05017
Spinocerebellar ataxia
llv05022
Pathways of neurodegeneration - multiple diseases
llv05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
llv00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
125086988
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
125086988
09143 Cell growth and death
04210 Apoptosis
125086988
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
125086988
05012 Parkinson disease
125086988
05014 Amyotrophic lateral sclerosis
125086988
05016 Huntington disease
125086988
05017 Spinocerebellar ataxia
125086988
05022 Pathways of neurodegeneration - multiple diseases
125086988
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
125086988
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
125086988
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
llv01001
]
125086988
Enzymes [BR:
llv01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
125086988
Protein kinases [BR:
llv01001
]
Serine/threonine kinases: Other
IRE family
125086988
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
Ribonuc_2-5A
PK_Tyr_Ser-Thr
PQQ_2
PQQ
Pkinase_fungal
Kdo
APH
PQQ_3
Motif
Other DBs
NCBI-GeneID:
125086988
NCBI-ProteinID:
XP_047562716
LinkDB
All DBs
Position
16:14692354..14770015
Genome browser
AA seq
975 aa
AA seq
DB search
MPVRLLLVLLALLLPGPGIFGSPSTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTLKEDP
VLQVPTHVEEPAFLPDPNDGSLYTLGGKNNEGLTKLPFTIPELVQASPCRSSEGILYMGK
KQDIWYVIDLLTGEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNATYF
DYAASLPEDDGDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYVWQREGLKKV
LHINVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLTPTLYVGKYSTSLYASPSMV
HEGVAVVPRGSTLPLLEGPQTDGVTIGDKGECVITPSTDVKFDPGLKGKNKLNYLRNYWL
LIGHHETPLSASTKMLERFPNNLPKHRENVIPADSEKKSFEEVINLVEQTSENAPTTVSQ
DVEEKYERAPAKPEAPMDSVLKDIATIILSTFLLIGWVAFIITYPLSMHQQQQLQHQQFQ
KELEKIQLLQQQQLPFHPPADVAQDAEPLDSSGLYSESSGTSSPSTSPRASNHSLHSSGS
ASKAGSSPFLEQDDEDEETNMVIVGKISFCPKDVLGHGAEGTIVYRGMFDNRDVAVKRIL
PECFSFADREVQLLRESDEHPNVIRYFCTERDRQFQYIAIELCAATLQEYVEQKDFAHLG
LEPITLLQQTTSGLAHLHSLNIVHRDLKPHNILLSMPNAHGRIKAMISDFGLCKKLAAGR
HSFSRRSGVPGTEGWIAPEMLSEDCKDNPTYTVDIFSAGCVFYYVISEGSHPFGKSLQRQ
ANILLGAYSLDCLHPEKHEDVIARELIENMIAMEPQKRPSAKHVLKHPFFWSLEKQLQFF
QDVSDRIEKESLDGPIVKQLERGGRAVVKMDWRENITVPLQTDLRKFRTYKGGSVRDLLR
AMRNKKHHYRELPTEVRETLGSLPDDFVRYFTSRFPHLLSHTYRAMEPCGHERLFQPYYF
HEPPEPWLPVTADTP
NT seq
2928 nt
NT seq
+upstream
nt +downstream
nt
atgccggtccggctgctgctggtgctgctggcgctgctgctgcctggccccgggattttt
ggaagtcccagcacagtgacgcttcctgaaaccttgttgtttgtgtcaactctggatgga
agtttgcatgctgtcagcaagaggacaggctcgatcaaatggactctaaaagaagatcca
gttctgcaagttccaacacatgtggaagagcctgccttcctcccagatcccaatgacggc
agcctgtatacgcttgggggcaagaataatgaaggcctgacgaaacttccttttaccatc
ccagagttggtacaggcatccccgtgccgaagttcagaaggaattctctacatgggtaaa
aagcaggacatttggtatgtcattgaccttctgaccggggagaagcagcagactctgtcg
tcagcctttgcagacagtctctgcccatcaacctctttgctgtatcttgggcgaacggaa
tacaccatcaccatgtacgacaccaaaacccgcgagctccggtggaacgccacctacttt
gactatgcagcctcgctgcctgaggacgacggggactacaagatgtcccactttgtgtct
aacggcgacgggctggtggtgaccgtggacagtgagtccggcgatgtcctgtggatccaa
aactacgcttcccccgtggtggccttttacgtctggcagcgggagggtctgaagaaggtg
ctgcacatcaacgtcgccgtggagaccctgcgctacctgaccttcatgtctggggaggtg
ggccgcatcaccaagtggaagtacccgttccccaaggagacggaggccaagagcaagctg
acgcccaccctgtatgtcgggaagtactctaccagcctgtatgcctccccctccatggtt
cacgagggagtcgctgttgtgccccgaggcagcactcttcctttgctggaaggcccccag
actgatggggtcaccatcggggacaaaggggagtgtgtgatcacgcccagcacagatgtc
aagtttgaccctgggctcaaaggcaagaacaaactcaactacctgaggaactactggctt
ctgataggacaccatgaaaccccgctgtccgcgtctaccaagatgctggagagattcccc
aacaacctgcccaaacatcgggaaaacgtgattcctgccgactcagagaagaagagcttt
gaggaagttatcaacctggttgaacagacttcagaaaacgcgcctaccaccgtctcacag
gatgtggaagagaaatacgagcgtgccccagccaagcctgaggcccccatggactctgtg
ctcaaggacatcgccaccatcatcctgagcaccttcctgctcattggctgggtggccttc
atcatcacctaccccttgagcatgcatcagcagcagcagctccagcaccagcagttccag
aaggaactagagaaaatccagctcctgcaacagcagcagctgcccttccatccacctgca
gacgtggctcaggatgctgagcccttggactcatccggcctgtactccgagagctcaggc
accagcagccccagcacatcccccagagcctccaaccactcactgcactccagtggctct
gcctccaaggctggcagcagccccttcctggagcaggatgatgaggatgaggaaaccaac
atggtgatagttgggaagatttcattctgtcccaaggacgtgctgggtcatggagctgag
ggcacgattgtgtaccggggcatgtttgacaaccgtgacgtggctgtcaagaggatcctc
cccgagtgtttcagtttcgcggaccgtgaggtccagctgcttcgagaatccgatgagcac
cccaatgtgatccgctacttctgcacggagagggaccggcagttccagtacattgccatc
gagctgtgcgctgccaccctgcaggagtacgtggagcagaaggactttgcccacctcggc
ctggagcccatcaccctgctacagcagaccacctcgggcctggcgcatctgcactccctc
aacattgttcacagagacctgaagccccacaacattctcctctccatgcccaacgcacat
ggcaggatcaaggccatgatctcggactttggcctgtgcaagaagctggccgcaggcagg
cacagcttcagccgccgctcaggagtgccgggcacggaaggctggatcgctccagagatg
ctgagcgaagactgcaaggacaacccgacctacacggtggacatcttctctgcgggctgt
gtcttttactacgtgatatcggagggcagccacccttttggcaagtccctgcagcggcag
gccaacatcctcctgggagcctacagcctggactgcttgcaccccgagaagcacgaagac
gtcattgcccgggaattaatagagaacatgatcgccatggagcctcagaaacgcccgtcc
gcaaaacacgtgctaaagcacccgttcttctggagcctggagaagcagctgcagtttttc
caggacgtgagtgaccgaatagaaaaggagtccctggacggcccaatagtgaagcagctg
gagcgaggtgggagagccgtggtgaagatggactggagggagaacatcactgtccccctg
cagacagatctgcggaaattcaggacctataaaggcggctccgtccgagacctcctccga
gccatgagaaacaagaagcaccactaccgggagctccccacggaggtgcgggagacgctg
ggctcccttcccgacgacttcgtgcgctacttcacgtcccgcttcccccacctcctctcc
cacacctaccgggccatggagccgtgcggccacgagcggctcttccagccctactacttc
cacgagcccccagagccctggcttccagtgactgcagacaccccttga
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