Lutra lutra (Eurasian river otter): 125091627
Help
Entry
125091627 CDS
T08100
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
llv
Lutra lutra (Eurasian river otter)
Pathway
llv00010
Glycolysis / Gluconeogenesis
llv00020
Citrate cycle (TCA cycle)
llv00620
Pyruvate metabolism
llv00785
Lipoic acid metabolism
llv01100
Metabolic pathways
llv01200
Carbon metabolism
llv01210
2-Oxocarboxylic acid metabolism
llv04066
HIF-1 signaling pathway
llv04922
Glucagon signaling pathway
llv05230
Central carbon metabolism in cancer
llv05415
Diabetic cardiomyopathy
Module
llv_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
llv00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
125091627
00020 Citrate cycle (TCA cycle)
125091627
00620 Pyruvate metabolism
125091627
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
125091627
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
125091627
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
125091627
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
125091627
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
125091627
Enzymes [BR:
llv01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
125091627
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
MIF4G_like
Motif
Other DBs
NCBI-GeneID:
125091627
NCBI-ProteinID:
XP_047571270
LinkDB
All DBs
Position
X:complement(84346101..84360065)
Genome browser
AA seq
389 aa
AA seq
DB search
MRKMLAAVSRVLGVAQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTREDG
LKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRAH
GFTFTRGLSVREILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALAC
KYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAASTD
YYKRGDFIPGLRVDGMDILCVREATRFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVSY
RTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPPL
EELGYHIYSSDPPFEVRGANQWIKFKSIS
NT seq
1170 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagatgctcgccgctgtctctcgcgtgttgggcgtcgcccagaagccggcaagc
agagtgctcgtggcctcccgtaattttgcaaatgatgctacatttgaaattaagaaatgc
gatcttcaccggctggaggagggccctcctgtcaccacagtgctcaccagggaggacggg
ctcaagtactacaggatgatgcagacggtccgccggatggagttaaaggcagatcagctg
tacaagcagaagattattcgtggtttctgtcacttgtgtgatggtcaggaagcttgttgt
gtgggcctggaggccggcataaatcctacagaccatctcatcacagcctatcgggctcat
ggctttaccttcactcgtgggctttctgtccgagaaattctcgcagagcttacaggacga
agaggaggctgtgctaaagggaaaggaggatcgatgcacatgtacgccaagaacttctac
gggggcaacggcatcgtcggagctcaggtgcccttgggagcggggattgctctggcctgt
aagtataacggaaaggatgaggtctgtctgactttatatggcgacggtgctgctaatcag
ggtcagatatttgaagcttacaacatggcagctttgtggaaactgccatgtattttcatc
tgtgagaataaccgctatggaatgggaacatctgttgagagagcagcggccagcacagac
tactacaagagaggcgacttcatccctgggctgagggtagatggaatggacatcttgtgt
gtccgggaggcaacaaggtttgcagctgcctactgtagatctggaaaggggcccatactg
atggagctacagacctaccgttaccacggacacagcatgagcgaccctggcgtcagttac
cgtacccgagaagagattcaggaagtaagaagtaagagtgaccctatcatgctgctcaag
gatagaatggtgaacagcaatctggccagcgttgaagaattaaaggaaattgatgttgaa
gtgaggaaggaaattgaggatgctgcccagtttgccactgctgatcctgaaccgcctttg
gaagagctaggctatcacatttacagcagcgatccgccttttgaagttcggggtgccaat
cagtggatcaagtttaagtccatcagttaa
DBGET
integrated database retrieval system
