Lutra lutra (Eurasian river otter): 125094265
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Entry
125094265 CDS
T08100
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial-like
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
llv
Lutra lutra (Eurasian river otter)
Pathway
llv00010
Glycolysis / Gluconeogenesis
llv00020
Citrate cycle (TCA cycle)
llv00620
Pyruvate metabolism
llv00785
Lipoic acid metabolism
llv01100
Metabolic pathways
llv01200
Carbon metabolism
llv01210
2-Oxocarboxylic acid metabolism
llv04066
HIF-1 signaling pathway
llv04922
Glucagon signaling pathway
llv05230
Central carbon metabolism in cancer
llv05415
Diabetic cardiomyopathy
Module
llv_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
llv00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
125094265
00020 Citrate cycle (TCA cycle)
125094265
00620 Pyruvate metabolism
125094265
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
125094265
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
125094265
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
125094265
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
125094265
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
125094265
Enzymes [BR:
llv01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
125094265
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Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
125094265
NCBI-ProteinID:
XP_047575879
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Position
2:97495623..97496978
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AA seq
391 aa
AA seq
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MKKMLTAAVSRVWSGVAQKPTSRVLVASCNFSKDATFEIKKCDLYRLEEGPPDTTVLTRE
DGLKYYRMMQTIRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLEAGINPTDHVITSYR
AHGLCYTRGLSVRSILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQGPLGAGIAL
ACKYKGKNEVCLTLYGDGAANQGQIAEAYNMAALWKLPCVFICENNLYGMGTSAERAAAS
TEYYKRGNFIPGLRVDGMDVLCVREATRFAADYCRSEKGPIVMELLTYRYHGHSMSDPGV
SYRTRQEIQNVRSKSDPIMLLKNRMVDSKLATIEEFKEIDVEVRKEIDDAVHFATTDPEP
VLEELGHHIYCDNPPFEVRGTSQWIKFKSLP
NT seq
1176 nt
NT seq
+upstream
nt +downstream
nt
atgaagaagatgctcaccgccgcggtctcccgagtgtggtctggggtcgcccagaagccc
actagcagagtgctcgtggcatcctgtaacttttcaaaagatgctacatttgaaattaag
aaatgtgacctttatcgattagaagagggtccccctgacacaacagtgctcacccgggag
gatgggcttaaatactacaggatgatgcagactattcgcagaatggaattgaaggcagat
cagctgtataaacaaaagtttattcgtgggttctgtcacttgtgcgatggtcaggaagct
tgttgcgtgggcctggaggctgggataaatcccacggatcatgtcatcacatcctacagg
gctcatggcttgtgctatactcgtggactttctgtcagatcaattctcgcagaactgaca
ggacggaggggaggctgtgctaaaggaaaaggaggatctatgcatatgtatgcaaagaac
ttctatgggggcaacggcatcgttggcgcccagggacccctaggagctggtattgccctg
gcctgtaaatataagggcaaaaatgaggtctgtttgactctctacggggatggtgctgcg
aatcagggccagatagcggaagcttacaatatggccgctttgtggaaattaccttgtgtt
ttcatctgtgagaataacctgtatggaatgggcacctctgccgagagagcagcagccagc
actgaatactacaagagaggaaattttatccctggactaagggtggatggaatggatgtt
ctatgtgttcgggaggcaactaggtttgcagctgactactgcagatctgaaaaggggccc
atagtgatggagctgctgacataccgttatcatggacacagcatgagtgaccctggagtg
agttatcgtacacgacaagaaattcagaatgtaagaagtaagagtgatcctattatgctt
ctcaagaatagaatggtagacagtaagcttgccactattgaagaattcaaggaaattgat
gtggaagtgaggaaagaaattgacgatgcagtccactttgctacaactgatcctgaacca
gttttggaggaattaggtcatcacatctactgcgataatccaccttttgaagttcgtggt
acaagtcagtggatcaagtttaagtctctcccttaa
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