Legionella lytica: J2N86_07235
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Entry
J2N86_07235 CDS
T08304
Symbol
folC
Name
(GenBank) bifunctional tetrahydrofolate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
lly
Legionella lytica
Pathway
lly00790
Folate biosynthesis
lly01100
Metabolic pathways
lly01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
lly00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
J2N86_07235 (folC)
Enzymes [BR:
lly01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
J2N86_07235 (folC)
6.3.2.17 tetrahydrofolate synthase
J2N86_07235 (folC)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
USQ12523
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Position
1617598..1618860
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AA seq
420 aa
AA seq
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MFKPYHEWSLAEWLSDLETRNVNEIQLGLARIQIVAERLQLLRPKCNVITVAGTNGKGST
VTALEHIYHTAGYKVGAYTSPHLIHFNERVRVGLTRINEDILCQAFALIESVRQDTVLTY
FEFITLAALWYFHQEQVDIIILEVGLGGRLDATNIIDADLSIITTIDLDHQDFLGDSLEV
IGYEKAGILRSGKPFIYADENPPASIVEVATALPVSSYYIGKEFSFEELDLTWSVYCGET
KIHDLPKPAIQLKSAAAAITASHILAQSLPVSYEHLQKAMESIFIPGRLQLQKGSVDVLY
DVSHNPQSARLLAKTLQHYGKKSKIHAVFSALKDKDILGLIVPLKDYVDYWYPAQLNVKR
AISANLLLSYFNDAEIFVKICYNEPLLAFKTALDQAKPGDLIVVYGSFFTVSHIMAVQSN
NT seq
1263 nt
NT seq
+upstream
nt +downstream
nt
ttgttcaagccttatcacgaatggagcttagctgaatggctatctgatctcgaaactcga
aatgtcaacgaaattcaattaggtttagctcgaattcaaatcgttgcagagcgattacaa
ttacttaggcctaaatgtaacgtcattaccgttgccggaacaaatggaaaaggttctaca
gtaaccgccttagaacatatttatcatacagctggttataaggtaggggcttatacctct
ccgcatcttattcattttaatgagcgtgtccgtgttggtttaacacgaataaatgaggac
atcttgtgtcaggcctttgctttaattgaatcagtacgccaggatacggtattaacttac
tttgaatttataacacttgctgcattatggtattttcaccaagagcaggtagatattatt
atccttgaggttggtttaggtgggcgtctggatgcaaccaatattattgatgcggatctt
tcaatcattactactattgatttggaccatcaggactttttaggtgatagtctggaggtg
attggttatgaaaaagcaggcattcttcgtagtggaaagccatttatttatgctgatgag
aatccccctgcaagcattgtcgaagtggctacagcattgcccgtttcttcttattatata
ggtaaggaattttcatttgaagaactcgatctgacttggagtgtttattgtggtgaaaca
aaaatacatgatttaccaaaaccggccatacaactgaaatcagccgccgctgcaattact
gcatcccatatattagcccagagcctccctgtgtcttacgagcatttacaaaaggcaatg
gagagtatttttattcctggacgtttgcaattacagaaggggagcgttgatgttctctat
gatgtatctcataatcctcaatctgcaaggttattagctaagactttgcagcattatggt
aaaaagtctaagattcatgctgtgttttcagcgttaaaagataaagatatccttggttta
attgtaccgttaaaggattatgttgattattggtatccggctcaattaaatgttaaacgc
gccattagtgcaaatttattgctttcttattttaatgatgcagaaatttttgtgaaaatt
tgttataatgagccgcttcttgcctttaaaacggcattagatcaggcaaaaccaggtgat
ttaatcgttgtttatgggtcattttttactgtgagtcatataatggctgtccagtctaat
tag
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