Leishmania major: LMJF_18_1660
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Entry
LMJF_18_1660 CDS
T01014
Symbol
GSH1
Name
(RefSeq) putative gamma-glutamylcysteine synthetase
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
lma
Leishmania major
Pathway
lma00270
Cysteine and methionine metabolism
lma00480
Glutathione metabolism
lma01100
Metabolic pathways
lma01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
lma00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
LMJF_18_1660 (GSH1)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
LMJF_18_1660 (GSH1)
Enzymes [BR:
lma01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
LMJF_18_1660 (GSH1)
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Gene cluster
GFIT
Motif
Pfam:
GCS
Motif
Other DBs
NCBI-GeneID:
5651098
NCBI-ProteinID:
XP_001682576
UniProt:
Q4QDM2
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All DBs
Position
18:729902..731965
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AA seq
687 aa
AA seq
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MGLLTTGGAPIQWGTDANSKAIPHVREHGIQQFLNVFKSKKDLHGMPFFWGEELEHQLIQ
LHDDTVTLSTEGAEVMNKLRARPDNCAVWNPEYGSFMVESTPDHPYTLSVESLDSVQDNI
ARRYHMLNEEAPPGVVGTTFVTFPLMGQGNFVHCSDKSSPYSQSLFVPDACINQTHPRFA
NLTANIRLRRGQKVCILVPLYVDSRTMQDTVDPRLNIDLTPHNKDIFHSRRENGRSMTDE
LYAHTDASAALLVPSSSLDPREDYPVTETLKQLFTPAALYYYAQYFTGQHREHMQERYNA
CNYPVTLVSHPCIYMDCMAFGMGNSALQVTMQLDNIHEARHVYDQLAILCPALLALSSAT
PFQKGLLCDTDVRWLTIAGAVDDRRVEEVPHILKSRYDSISVFISDRTENLEEFNDSQIA
INRSYYELLKDSGVDVRLANHIAHLFIRDPLVMYDKMIDIDDTTHTEHFDNIQSTNWQTV
RFKPPPLGNDIGWRVEFRVMDIQPTPFENAAFAVFIPLLTKAIVNYKPCFYTKISIVDEN
MGRAHRINPCGEQYIMRKDIFAHKCTASDEETARMSIDEIFNGKEGGFYGLIPLVCRYLD
DEGKRSPLVNSYLKFLSMRASGRIPTPAQYMRKFVTTHPDYKHDSRLTDSIARDLVQRMH
GLASNQIHDDDYLPISVFKATTRESVK
NT seq
2064 nt
NT seq
+upstream
nt +downstream
nt
atggggctcttgacgactggcggcgccccaatacaatggggcaccgatgcaaatagcaaa
gccattccgcacgtcagagagcacggcattcaacagttcctcaacgttttcaaaagcaaa
aaggacctccatggtatgccgtttttctggggagaggagctggagcaccagctgatccag
ctccacgatgacacggttaccctcagcacagaaggtgcggaggtaatgaacaagctgagg
gcgcgtcctgacaactgtgccgtgtggaatcccgaatatggaagcttcatggtcgaaagc
acgccagaccacccttacactctgtcggtggagagcctcgactcggtgcaggacaacatc
gcgcggcggtaccacatgctcaacgaggaggcgccacccggcgtggtcggcaccaccttt
gtgactttcccactcatgggccagggtaactttgtacactgcagtgataagagctctccg
tactcgcagtcgctgtttgttcctgatgcgtgcatcaaccaaacgcatccgcgctttgcg
aacctgacggcaaacattcgcctgcgccgcggtcaaaaggtttgcatcctggtgcctctg
tacgtggactcccgaacaatgcaggacacggtggacccccgactaaacattgacctgact
ccacacaacaaggacatttttcactccaggagagaaaacggcaggagcatgaccgacgaa
ctctacgcgcacacggacgcgtctgccgctctgctagtgccgagtagctctctcgaccca
cgcgaggactaccctgtcaccgagactctgaagcagctcttcacccctgctgcgctctac
tactacgcacagtacttcacgggacagcaccgcgagcatatgcaggagcgctacaacgcg
tgtaactaccccgtaaccttggtcagccacccgtgcatctacatggactgcatggccttt
ggcatgggtaacagcgctctgcaagtgacgatgcagctggacaacattcacgaggcgcgc
cacgtgtacgaccagctcgccatcttgtgcccggcgcttctggctctcagctcagccacg
ccgttccagaagggtcttctttgcgacaccgatgtgcgctggctgactattgccggcgcc
gtcgacgaccgccgcgtggaggaggtgccgcatatcctcaagtctcgctacgactccatc
tccgtcttcatcagcgacagaaccgaaaacctcgaggaattcaacgattcacagatagcg
ataaaccgctcgtactatgaactcctgaaggactccggtgtcgacgtgcggttggcgaac
cacattgcacatctgttcattcgagatccgcttgtgatgtacgacaagatgatcgacatc
gatgacacgacgcacacagagcactttgacaacatccagtccactaactggcagacagtg
cgcttcaagcctccgccgctaggcaacgacattggctggcgcgttgagttccgcgtgatg
gatattcagccaacgccgttcgagaacgccgccttcgccgtcttcattccgcttctcacc
aaggccatcgtcaactacaagccctgcttttacaccaagatctccatcgtcgacgagaat
atgggccgcgcacatcgcatcaacccatgtggagaacaatacattatgcgcaaggacatt
ttcgcccacaagtgcaccgccagtgacgaggagacggcgaggatgagcattgacgagatc
ttcaacggcaaggagggcggattctatggactcatccccctcgtgtgccgctatctcgac
gacgaggggaagcgaagtcccctcgtaaactcctacttgaagttcctgtcaatgcgcgcc
tctggccgcattcccacacctgcgcagtacatgcgaaagtttgtcacgacacatcccgac
tacaaacacgactcacgcctcaccgacagcatcgcacgtgaccttgtgcagcgcatgcac
ggtctggcttcgaatcagatccacgacgatgactaccttcccataagcgtcttcaaggcc
accacaagagagagtgtcaagtga
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