Leishmania mexicana: LMXM_18_1380
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Entry
LMXM_18_1380 CDS
T02288
Name
(RefSeq) putative pyruvate dehydrogenase E1 component alpha subunit
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
lmi
Leishmania mexicana
Pathway
lmi00010
Glycolysis / Gluconeogenesis
lmi00020
Citrate cycle (TCA cycle)
lmi00620
Pyruvate metabolism
lmi00785
Lipoic acid metabolism
lmi01100
Metabolic pathways
lmi01110
Biosynthesis of secondary metabolites
lmi01200
Carbon metabolism
lmi01210
2-Oxocarboxylic acid metabolism
Module
lmi_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
lmi00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
LMXM_18_1380
00020 Citrate cycle (TCA cycle)
LMXM_18_1380
00620 Pyruvate metabolism
LMXM_18_1380
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
LMXM_18_1380
Enzymes [BR:
lmi01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
LMXM_18_1380
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Motif
Pfam:
E1_dh
DXP_synthase_N
GvpL_GvpF
Motif
Other DBs
NCBI-GeneID:
13447686
NCBI-ProteinID:
XP_003874149
UniProt:
E9ARS2
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All DBs
Position
18:570681..571817
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AA seq
378 aa
AA seq
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MLKCATRFLLDTKTVSLKPQRPFKLHTAGRTDMAPLPTQAAYDTEQLKKSLALMFRIRRM
ESLCDQSYKLKKIRGFCHLYIGQEAIPAGMENVLSFEDPIVTGYRDHGWYISRGGKPEDV
FAEMFGRQGGCSKGKGGSMHMYKVGNGFYGGNGIVGAQVSIGAGLAWRFAMENRDSPKHV
AVTFYGDGAANQGQIYESMNIAALQRLPVIFAVENNHFGMGTSAARGSYQSEFYRRGDYI
PGIKVDGMDVLAVQEGTRYARDHCMSGKGPIVMELDCYRYMGHSMSDPDNQYRTKNDIQH
VKQERDCIRKMRELMATEGIMTEDEMNKLEKDVKKEVDQDLQKAQKQAMTKLDELFTDIY
VGEQYEHRTCQGTVYHKP
NT seq
1137 nt
NT seq
+upstream
nt +downstream
nt
atgctcaagtgcgcgactcgcttccttctggacaccaagacggtttcgctgaagccgcag
cgcccattcaagctccacacggcaggccgcaccgacatggcaccactgccgacgcaggcg
gcgtacgacacggagcaactgaagaagagtcttgccctgatgttccgcatccgccgcatg
gagtctctgtgcgatcagtcctacaagctaaaaaaaattcgcggcttctgccacctctac
attgggcaggaggccatcccggctggcatggagaacgttctgtccttcgaggaccccatc
gttactggctaccgcgaccacggctggtacatctctcgcggtggcaagcccgaggatgtc
ttcgccgaaatgttcggccgtcagggcggctgcagcaagggcaagggtggctcgatgcac
atgtacaaggtgggcaacggcttctacggcggtaatggtatcgtcggtgcgcaggtctcc
atcggcgctggccttgcctggcgcttcgcgatggagaaccgcgacagcccgaagcacgtc
gcggtcaccttctacggcgacggtgctgccaaccagggccagatctacgagtccatgaac
attgccgctctgcagcgcctccctgtcatcttcgctgtggagaacaaccactttggcatg
ggcactagcgccgctcgcggctcctatcagtcggagttctaccgccgtggtgactacatc
cctggtatcaaggtggatggcatggacgtgctcgcggtgcaggagggcacccgctacgca
cgagaccactgcatgtcgggcaagggcccgatagtgatggagctggactgctaccgctac
atgggccatagcatgtcggaccccgacaaccagtaccgcaccaagaacgacatccagcat
gtgaagcaggagcgtgactgcattcggaagatgcgcgagctcatggcgaccgagggcatc
atgaccgaggacgagatgaacaagttggagaaagacgtaaagaaggaggtggaccaggac
ctgcagaaggcccagaaacaagcgatgacaaagttggatgaactcttcacggatatctac
gtgggtgagcagtacgagcaccgcacctgccagggtaccgtgtaccacaagccctaa
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