Leishmania mexicana: LMXM_18_1660
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Entry
LMXM_18_1660 CDS
T02288
Name
(RefSeq) putative gamma-glutamylcysteine synthetase
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
lmi
Leishmania mexicana
Pathway
lmi00270
Cysteine and methionine metabolism
lmi00480
Glutathione metabolism
lmi01100
Metabolic pathways
lmi01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
lmi00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
LMXM_18_1660
09106 Metabolism of other amino acids
00480 Glutathione metabolism
LMXM_18_1660
Enzymes [BR:
lmi01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
LMXM_18_1660
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Motif
Pfam:
GCS
Motif
Other DBs
NCBI-GeneID:
13447699
NCBI-ProteinID:
XP_003874178
UniProt:
E9ARV1
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Position
18:682498..684561
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AA seq
687 aa
AA seq
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MVFLTDGGAAIQWGTDAHSKAIPHVREHGIQQFLNVFKNKKDLHGMPFLWGEEVEHQLIQ
IHDNTVTLSTESEMVINKLRARPDSCAVWNFEYGSFMVESTPDHPYNLSVESLDSVQDNI
ARRYDMLNKEAPPGVVGTTFVTFPLMGQGNFVHCSSKSSPYSQSLFVPDACINQTHPRFA
NLTANIRLRRGQKVCILVPLYMDTRTMENTVDPRLNIDLTPRNNDIFYSMRENGRNTTDE
LYAETDAFAAPLVPRSSIDPREDYPATETLRQLFTPATLRYYAQYFTEEHREHMQELYNA
CPCPVPLVSHPCIYMDCMAFGMGSSALQVTMQLDNIHEARHVYDQLAILCPAFLALSSAT
PFQKGLLCDTDVRWLTIAGAVDDRRAEEVPRILKSRYDSISVFISDRTENLEEFNDSHIE
VNRSYCELLKDSGVDVRLANHIAHLFIRDPLVMYDKMIDIDDTTHTEHFDNIQSTNWQTM
RFKPPPIGSDIGWRVEFRVMDIQPTPFENAAFAVFIPLLTKAIVNYKPCFYTKISIVEEN
MSRAHRINPCGEQYVMRKDIFANKCTASDEETARMSIDEIFNGKEDGFYGLIPLVCRYLD
SEGKRSPLINSYLKLLSMRASGSIPTPAQYMRRFVTTHPDYKHDSRLTDSIARDLVQHMH
SLASNQIHDDDYLPMSIFRVDSVESTK
NT seq
2064 nt
NT seq
+upstream
nt +downstream
nt
atggtattcttgacggatggcggcgccgcgattcagtggggcaccgacgcacatagcaag
gccattccgcacgtcagagagcatggcattcagcagttcctcaacgttttcaagaacaag
aaggacctacatggcatgccgtttctctggggcgaggaggtggaacaccagctgatccag
atccacgataacacggttaccctcagcacagaaagtgagatggtaattaacaagctgaga
gcgcgtcctgacagctgcgccgtgtggaacttcgaatatggcagcttcatggtagaaagc
acgccagaccacccgtacaatctgtcagtggagagcctcgactcagtgcaggacaacatc
gcgcgacggtacgacatgctcaacaaggaggcgccacctggcgtggtcggcaccaccttt
gtgactttcccactcatgggccagggtaactttgtccactgcagtagcaagagctctccg
tactctcagtcgctttttgttcccgatgcgtgcatcaaccaaacgcatccgcgcttcgcg
aacctgacggcaaacattcgcttgcgccgcggccaaaaggtttgcatcctggtgcctctg
tacatggacacacgtacaatggagaacacggtggaccctcgactgaacattgacctgact
ccacgcaacaatgacattttttactccatgagagaaaacggcaggaataccaccgacgag
ctctacgcggagacggacgcgtttgccgctcctctagtgcccaggagctctatcgatcca
cgcgaggactacccggccaccgagacgctgaggcaactcttcacccctgccacactccgc
tactacgcacagtacttcacggaagagcaccgcgagcatatgcaggaactctacaacgcg
tgtccctgccctgtacccttggtgagccacccgtgcatctacatggactgcatggccttt
ggcatgggtagcagcgctctgcaagtgacgatgcagctggacaacattcacgaggcgcgc
cacgtgtatgaccagctcgccatcttgtgcccggcatttctggctctcagctcagccacg
ccgtttcagaagggtcttctttgcgacaccgatgtgcgctggctgactatcgccggcgct
gtggacgaccgccgcgccgaggaggtgccgcgtattctcaagtcgcgctacgactccatc
tccgtcttcatcagtgacagaaccgaaaacctcgaggagttcaacgattcacacatagag
gtgaaccgctcgtactgtgaacttctgaaggactccggtgtggacgtgcggttggcgaac
cacattgcacatctgtttattcgcgatccccttgtgatgtacgacaagatgatcgacatc
gatgacacgacgcacacggagcactttgataacatccagtccactaattggcagacaatg
cgcttcaagcctccgccgataggcagcgacattggctggcgcgttgagtttcgagtgatg
gatattcagccaacaccattcgagaacgccgccttcgctgtcttcattccgcttctcacc
aaggccatcgtcaactacaagccctgcttttacaccaaaatctccatcgtcgaggagaat
atgagtcgcgcacatcgcatcaacccctgtggagaacaatacgttatgcgtaaggacatt
tttgccaacaagtgcaccgccagcgacgaggagacagcgaggatgagcattgacgagatc
ttcaacggcaaggaggacggcttctatggactcatccccctcgtgtgccgctatctcgac
agcgagggaaagcgaagtcccctcataaactcctacttgaagctcctgtcaatgcgcgcc
tctggcagcattcccacacctgcgcagtacatgcgcaggtttgtcacaacgcaccccgac
tacaagcacgactcacgcctcaccgacagtatcgcacgtgaccttgtccagcacatgcac
agcctggcctcgaatcagatccacgacgatgactatcttccgatgagcatcttcagggtc
gattcagtagaaagcaccaagtga
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