Leishmania panamensis: LPMP_181340
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Entry
LPMP_181340 CDS
T06539
Name
(RefSeq) pyruvate dehydrogenase E1 component alpha subunit, putative
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
lpan
Leishmania panamensis
Pathway
lpan00010
Glycolysis / Gluconeogenesis
lpan00020
Citrate cycle (TCA cycle)
lpan00620
Pyruvate metabolism
lpan00785
Lipoic acid metabolism
lpan01100
Metabolic pathways
lpan01110
Biosynthesis of secondary metabolites
lpan01200
Carbon metabolism
lpan01210
2-Oxocarboxylic acid metabolism
Module
lpan_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
lpan00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
LPMP_181340
00020 Citrate cycle (TCA cycle)
LPMP_181340
00620 Pyruvate metabolism
LPMP_181340
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
LPMP_181340
Enzymes [BR:
lpan01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
LPMP_181340
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GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
SCD
Motif
Other DBs
NCBI-GeneID:
22574024
NCBI-ProteinID:
XP_010697968
UniProt:
A0A088RNA3
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Position
18:559198..560334
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AA seq
378 aa
AA seq
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MFKCATRCLLATKKTLLKPQRPFKLHAATRTDMAPLPTEATYDTEQLKKSLTLMFRIRRM
ESLCDQSYKLKKIRGFCHLYIGQEAIPAGMENILTFEDPIVTGYRDHGWYIARGGTPEEV
FAEMFGRQGGCSKGKGGSMHMYSVRNGFYGGNGIVGAQVPIGAGLAWRFAMENRDSPKHV
AVTFYGDGAANQGQIYESMNIAALQRLPVIFAVENNHFGMGTSAARGSYQSEFYRRGDYI
PGIRIDGMDVLAVQEGTRYARDHCMSGKGPIVMELDCYRYMGHSMSDPDNQYRTKSDIQH
VKQERDCIRKMRDFMATEGIMTEEEMSKMEKEVKKEVDQDLQKAQKHPTTKLDELFTDVY
VGEQYEHRTCQGTVYQKP
NT seq
1137 nt
NT seq
+upstream
nt +downstream
nt
atgttcaagtgcgcaactcgctgcctgctggccaccaagaaaacattgctgaagccgcag
cgcccattcaagctgcacgcggctacccgcaccgacatggcgccactgccgacggaggcg
acgtacgacacggagcaactgaagaagagccttactttgatgttccgcatccgccgtatg
gagtctctgtgcgatcagtcctacaaactgaagaagattcgcggcttctgtcacctctat
attgggcaggaagccatccccgctggcatggaaaacatcctgaccttcgaggatcctatc
gtcactggctaccgcgaccacggctggtacattgcccgcggtggcacgcccgaggaggtc
tttgctgaaatgttcggtcgccaaggcggctgcagcaagggcaagggcggctcaatgcac
atgtacagcgtgcgtaatggtttctacggtggtaatggtatcgttggtgcgcaggtcccc
atcggtgcaggtctcgcctggcgcttcgcgatggagaaccgagacagcccgaagcacgtc
gcggttaccttctacggcgacggcgccgccaaccagggccagatctacgagtccatgaac
attgctgctctgcagcgcctacccgtcatcttcgctgtggagaacaaccacttcgggatg
ggcaccagcgccgctcgcggctcttatcagtcggagttctaccgtcgtggcgactatatc
cctggtatcaggatcgacggcatggacgtgctcgcggtgcaggagggcacccgctacgcg
cgcgaccactgcatgtcaggcaagggcccgattgtgatggaattggattgctaccgctac
atgggccatagcatgtcggaccccgacaaccagtaccgtaccaagagtgacatccagcac
gtgaaacaggagcgtgactgcattcgcaagatgcgcgatttcatggccaccgagggcatc
atgaccgaggaggaaatgagcaagatggagaaggaggtgaagaaggaggtggaccaggac
ctgcagaaggcccagaagcaccccacgaccaagttggatgagctcttcacggacgtctac
gtgggcgagcaatacgagcaccgcacctgccagggcaccgtgtaccagaagccgtaa
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