Leclercia pneumoniae: KQ929_17540
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Entry
KQ929_17540 CDS
T08189
Symbol
thrA
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
lpnu
Leclercia pneumoniae
Pathway
lpnu00260
Glycine, serine and threonine metabolism
lpnu00261
Monobactam biosynthesis
lpnu00270
Cysteine and methionine metabolism
lpnu00300
Lysine biosynthesis
lpnu01100
Metabolic pathways
lpnu01110
Biosynthesis of secondary metabolites
lpnu01120
Microbial metabolism in diverse environments
lpnu01230
Biosynthesis of amino acids
Module
lpnu_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
lpnu_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
lpnu_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
lpnu00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
KQ929_17540 (thrA)
00270 Cysteine and methionine metabolism
KQ929_17540 (thrA)
00300 Lysine biosynthesis
KQ929_17540 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
KQ929_17540 (thrA)
Enzymes [BR:
lpnu01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
KQ929_17540 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
KQ929_17540 (thrA)
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SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
NAD_binding_3
ACT_7
ACT
Sacchrp_dh_NADP
Motif
Other DBs
NCBI-ProteinID:
QWW79020
LinkDB
All DBs
Position
complement(3589943..3592405)
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AA seq
820 aa
AA seq
DB search
MRVLKFGGTSVANAERFLRVADILESNARQGQVATVLSAPAKITNHLVAMIEKTIGGQDA
LANISDAERIFAELLQGLADAQPGFPLAQLKAFVEQEFAQIKHVLHGISLLGQCPDSINA
ALICRGEKLSIAIMAGVLEARGHNVTVIDPVEKLLAVGHYLESTVDIAESTRRIAAGKIP
ADHMILMAGFTAGNEKGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPRQV
PDARLLKSMSYQEAMELSYFGAKVLHPRTISPIAQFQIPCLIKNTGNPQAPGTLIEASSD
EDGLPVKGISNLNNMAMFSVSGPGMKGMVGMAARVFAAMSRNGISVVLITQSSSEYSISF
CVPQSDCLRARRALEEEFYLELKEELLEPLSIQERLAVISVVGDGMRTLRGISAKFFAAL
ARANINIVAIAQGSSERSISVVVDNDDATTGVRVTHQMLFNTDQVIEVFLIGVGGVGSAL
LEQVKRQQTWLKNKHIDLRICGVANSKALLTNVHGLNLENWQAELAEAKEPFNLGRLIRL
VKEYHLLNPVIVDCTSNQVVADQYADFLREGFHVVTPNKKANTSSMAYYHQLRHAAAKSR
RKFLYDTNVGAGLPVIENLQNLLNAGDELQRFSGILSGSLSFIFGKLDEGMSLSEATRLA
REMGYTEPDPRDDLSGMDVARKLLILARETGRELELSDIVIEPVLPASFDDKGDVADFMS
RLSQLDDLFAARVAKARDEGCVLRYVGNIEEDGVCRVKIAEVDGNDPLFKVKNGENALAF
YSHYYQPLPLVLRGYGAGNDVTAAGVFADLLRTLSWKLGV
NT seq
2463 nt
NT seq
+upstream
nt +downstream
nt
atgcgagtgttgaagttcggcggtacatcagtggcaaatgcagaacgttttctgcgggtt
gccgacatcctggaaagcaatgccaggcaggggcaggtagcaacggtgctctctgccccg
gccaaaattactaaccatctggtggcgatgattgaaaaaaccatcggtggccaggatgcg
ctggcgaatatcagcgacgccgaacgcattttcgccgagctgttgcagggcctggccgat
gcccagcccggttttcccctcgcgcaactgaaagcgtttgttgagcaagagttcgcgcag
atcaaacacgtactgcatggtatcagcctgttagggcaatgcccggacagcatcaatgcg
gcgctcatctgccgcggtgaaaaactctctatcgctatcatggcaggcgtactggaagcg
cgtggccataacgtcaccgtgatcgatccggtggaaaagcttctcgccgtaggtcactac
ctcgaatctaccgttgatattgccgaatcaacccgtcgtatcgctgcagggaaaattcct
gccgaccacatgatcctgatggcgggcttcaccgccggaaatgagaaaggcgagctcgtc
gtgctggggcgtaatggttctgattactctgccgcggtactggcggcctgcctgcgcgcc
gactgttgtgagatctggactgacgtcgatggggtctatacttgcgatccgcgccaggtg
ccggatgcgcgcctgctgaagtcaatgtcttaccaggaggcgatggagctctcctacttc
ggcgccaaagtgctccacccgcgtaccatctctccgattgcccaattccagatcccctgc
ctgattaaaaatacgggtaatccgcaggcacctggcacgctgattgaggcgagcagcgat
gaagatggcctgccggtgaaaggcatttctaacctgaacaacatggcgatgttcagcgtc
tctggtcccggaatgaaaggcatggtcggtatggcggcccgcgtgtttgccgccatgtcg
cgcaatggcatctcggtggtactgatcacccaatcctcttctgagtacagcatcagtttt
tgcgtccctcagagcgactgtctgcgtgcacgccgggcgctggaagaggagttctatctg
gagctgaaagaggagttgcttgagccgctctccattcaggagcgtctggccgttatctcg
gttgtaggcgatggcatgcgtaccctgcgcggcatctccgcgaagttctttgccgcactg
gctcgcgccaatatcaacatcgtggccattgcgcagggctcttctgagcgttcaatctcc
gtggtggtggataatgacgatgcgacgaccggtgtgcgcgttacccaccagatgctgttc
aacaccgaccaggtgatcgaagtgttcctgatcggtgtaggcggcgtcggcagcgcgctg
ttggagcaggtcaagcgccagcagacgtggctgaagaacaaacatatcgatctgcgcatc
tgtggcgtggcgaactcaaaagcgctgctgaccaacgtgcatggcctgaatctggaaaac
tggcaggctgaactggccgaagccaaagagccctttaaccttgggcgcctgatccgcctg
gtgaaagagtaccatctgctcaacccggtcattgtcgactgtacgtcgaaccaggttgtc
gccgatcagtacgccgacttcctgcgcgaaggcttccatgtggtcaccccgaacaaaaaa
gccaacacttcgtcgatggcctattaccatcaactgcgccacgcagcggcaaaatcgcga
cgcaaattcctttacgataccaacgtcggggcagggctgccggttatcgaaaacctgcaa
aacttgctgaatgccggcgatgaactgcaacgtttctccgggatcctctcaggctcgctc
tcgttcattttcggtaaactcgacgagggcatgagcctctctgaagctacccgattagcc
cgtgagatgggctacaccgagccggatccgcgtgatgatctttctggtatggatgtggcg
cgtaagctgctgatcctcgcccgtgaaaccgggcgcgaactggagttgagcgacatagtg
atcgaacctgtgctacccgcatccttcgatgacaagggcgacgtggctgactttatgagc
cggttgtcgcagctggacgatctctttgctgctcgcgtagcgaaagcccgtgatgaaggt
tgcgtattgcgctatgttggcaatatcgaagaggacggcgtttgtcgggtgaagattgca
gaagtggacggtaacgatccgctgttcaaagttaaaaacggcgagaatgcgctggcattt
tacagtcactattatcagccattgccgttagtgcttcgcggttatggcgcagggaatgat
gtgacagcggcgggggtgtttgccgatctgttgcgtaccctgtcatggaagttaggagtt
taa
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