Leptonychotes weddellii (Weddell seal): 102747992
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Entry
102747992 CDS
T08708
Symbol
GCLC
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit isoform X1
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
lww
Leptonychotes weddellii (Weddell seal)
Pathway
lww00270
Cysteine and methionine metabolism
lww00480
Glutathione metabolism
lww01100
Metabolic pathways
lww01240
Biosynthesis of cofactors
lww04216
Ferroptosis
Module
lww_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
lww00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
102747992 (GCLC)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
102747992 (GCLC)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
102747992 (GCLC)
Enzymes [BR:
lww01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
102747992 (GCLC)
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Paralog
GFIT
Motif
Pfam:
GCS
GCS2
Motif
Other DBs
NCBI-GeneID:
102747992
NCBI-ProteinID:
XP_006745360
UniProt:
A0A2U3YNQ6
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Position
Unknown
AA seq
637 aa
AA seq
DB search
MGLLSQGSPLSWEETKRHADHVRRHGILQFLHIYHAVKDRHKDVLKWGDEVEYMLVSFDH
ENKKVRLVLSGEEVLETLQEKGERTNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
EDNMRKRRKEATSLLGENQALCTITSFPRLGCPGFTLPEFKPSPVEGGASKSLFFPDEAI
NKHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPSPFIEAFPEDEEAAKASKPDHIYMDA
MGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYVSDIDCRWGVI
SASVDDRTREERGLEPLKNNNYRISKSRYDSIDSYLSECGEKYNDIDLTIDKEIYEQLLQ
EGIDRLLAQHVAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFKPPPPNSDI
GWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRDAVL
QGMFYFRKDICKGGTTMVDGYSKAQNSTEQAVEEYTLMSIDTIINGKEAVFPGLIPILNS
YLENMEVDVDTRCSILNYLKLIKKRASGELMTVARWMREFIANHPDYKQDSVITDEMNYS
LILKCNQIANELCECPELLGPALRKVKYSGSKTDSSN
NT seq
1914 nt
NT seq
+upstream
nt +downstream
nt
atggggctgctgtcccagggctcgccgctgagctgggaggagaccaagcgccacgccgac
cacgtgcggcggcacgggatcctccagttcctgcacatctaccacgccgtcaaggaccgg
cacaaggacgtgctcaagtggggcgacgaggtggaatacatgttggtgtcttttgatcat
gaaaataagaaagtccggttggtcctgtccggagaggaagttcttgaaactctacaagaa
aagggggaaaggacaaacccaaaccatcctaccctgtggagaccagagtatggcagttac
atgattgaaggtacacccggacagccgtatggaggaacaatgtccgagttcaacacagtc
gaagacaacatgaggaaacgtcggaaggaagcgacttctttattaggagaaaaccaggct
ctctgcacaataacttcatttcccagattaggctgtcctgggttcacgctgccagagttc
aaacccagtccagttgaaggaggagcttccaagtccctcttctttcctgatgaagccata
aacaagcacccccgcttcagtaccctaacaagaaatatccgacacaggagaggagaaaag
gttgtcatcaatgtaccaatatttaaggacaagaatacaccctctccatttatagaagca
tttcctgaggatgaggaggcagccaaggcttctaagcctgatcatatttacatggatgcc
atgggatttgggatgggcaattgctgtcttcaggtaacgttccaagcctgcagcatatct
gaggccagatacctgtacgatcagttggccactatctgtccaattgtcatggctttgagc
gctgcatctcctttttaccgaggctatgtgtctgacattgattgtcgctggggagtgatt
tctgcatctgtagatgatagaactcgggaggagagaggactggagccactgaagaacaat
aactataggatcagtaagtcccgatatgattcgatagacagttacttatctgagtgcggt
gagaagtacaatgacatcgacttgacgatagataaagaaatctacgaacaactgttgcag
gaaggcattgatcgtctcctggcccagcatgttgctcatctcttcattagagacccactg
actctgttcgaagagaaaatacacttggatgatgccaatgaatctgaccattttgagaat
attcagtccacaaattggcagacgatgagatttaaaccccctcctccaaactcagatatt
ggatggagagtagaattccgacccatggaggttcagttaacagactttgagaactctgca
tatgtggtgtttgtggtgctgcttaccagagtgatcctttcatacaaactggattttctc
attccactatcaaaggttgatgaaaacatgaaagttgcacagaaacgcgatgctgtcttg
cagggaatgttttatttcaggaaagatatttgcaaaggtggcaccaccatggtggacggc
tacagcaaggcccagaacagcacggaacaggcagtagaggagtacaccctgatgagcata
gacaccatcatcaacgggaaggaagctgtgtttcctgggctgatcccaattctgaactct
taccttgaaaacatggaagtggatgtggacaccagatgcagtattctgaactacctaaag
ctaattaagaagagagcatctggagaactaatgacagttgccaggtggatgagagagttt
atcgcaaaccatcctgactacaagcaagacagtgtgataactgatgaaatgaactatagc
cttattttaaagtgtaaccaaattgcaaatgaattatgtgaatgcccagagttacttgga
ccagcattaaggaaagtaaaatacagtggaagtaaaactgactcttccaactag
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