Leptonychotes weddellii (Weddell seal): 102749675
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Entry
102749675 CDS
T08708
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial-like isoform X1
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
lww
Leptonychotes weddellii (Weddell seal)
Pathway
lww00010
Glycolysis / Gluconeogenesis
lww00020
Citrate cycle (TCA cycle)
lww00620
Pyruvate metabolism
lww00785
Lipoic acid metabolism
lww01100
Metabolic pathways
lww01200
Carbon metabolism
lww01210
2-Oxocarboxylic acid metabolism
lww04066
HIF-1 signaling pathway
lww04922
Glucagon signaling pathway
lww05230
Central carbon metabolism in cancer
lww05415
Diabetic cardiomyopathy
Module
lww_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
lww00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
102749675
00020 Citrate cycle (TCA cycle)
102749675
00620 Pyruvate metabolism
102749675
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
102749675
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
102749675
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
102749675
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
102749675
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
102749675
Enzymes [BR:
lww01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
102749675
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Paralog
GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
102749675
NCBI-ProteinID:
XP_006740442
UniProt:
A0A2U3Y9N7
LinkDB
All DBs
Position
Unknown
AA seq
391 aa
AA seq
DB search
MKKMLAAAVSRVLSGVAQKPASRVLVASCNYSNDATFEIKKCDLYRLEEGPPVTTVLTRE
DGLKYYRMMQTIRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLEAGINPTDHVITSYR
AHGLCYTRGLSVRAILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQGPLGAGVAL
ACKYKGKKEVCLTLYGDGAANQGQIFEAYNMAALWKLPCVFVCENNLYGMGTSAERAAAS
TDYYKRGHFIPGLRVDGMDVLCVREATRFAADYCRSEKGPIVMELQTYRYHGHSMSDPGV
SYRTRQEIQNVRSKSDPIMLLKDRMVNSKLATVEEFKEIDVEVRKEIDDAAHCATTDPEP
PLEELGHHIYCDNPPFEVRGASQWIKFKSLS
NT seq
1176 nt
NT seq
+upstream
nt +downstream
nt
atgaagaagatgctcgccgccgcggtctcccgcgtgttgtccggggttgcccagaagccc
gctagcagagtgctggtggcatcctgtaactattccaatgatgccacatttgaaattaag
aaatgtgacctttatcgattagaagagggcccccctgtcacaacagtgctcacccgggaa
gatgggcttaaatactacaggatgatgcagactattcgccgaatggaattgaaggcagat
cagctgtataaacaaaaatttattcgtgggttctgtcacttgtgcgatggtcaggaagct
tgttgtgtgggcctggaggctgggataaatcccaccgatcatgtcatcacatcctatcgg
gctcacggcttgtgctatactcgtggactttctgtccgagcaattcttgcagaactgaca
ggacgaagaggaggctgtgctaaaggaaaaggaggatctatgcatatgtatgcaaagaac
ttctatgggggcaacggcattgtcggcgcccaggggcccctgggagctggtgtcgccctg
gcctgtaaatataagggcaaaaaggaggtctgtttgaccctgtatggggatggtgctgcg
aatcagggtcagatatttgaagcttacaatatggctgctctgtggaaattaccttgtgtt
ttcgtctgtgagaataacctctatggaatgggcacatctgctgagagagcagcagcaagc
actgattactacaagagaggacactttatccccggactaagggtggatggaatggatgtt
ctgtgtgttcgggaggcaacgaggtttgccgcggactactgtagatctgaaaaggggccc
atagtgatggagctgcagacataccgttatcatggacacagcatgagtgaccctggagtt
agttaccgcacgcgacaagaaattcagaatgtaagaagtaagagtgatcctattatgctt
ctcaaagatagaatggtaaacagtaagcttgccactgttgaagaattcaaggaaattgat
gtagaagtgaggaaagaaattgacgatgcagcccactgtgctacaactgatcctgaacca
cctttggaagagttaggtcatcacatctattgcgataatccaccttttgaagttcgtggt
gcaagtcagtggatcaagtttaagtccctcagttaa
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