Mycobacterium tuberculosis variant africanum: MAF_24640
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Entry
MAF_24640 CDS
T01575
Symbol
folC
Name
(GenBank) putative folylpolyglutamate synthase protein FOLC (folylpoly-gamma-glutamate synthetase)
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
maf
Mycobacterium tuberculosis variant africanum
Pathway
maf00790
Folate biosynthesis
maf01100
Metabolic pathways
maf01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
maf00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
MAF_24640 (folC)
Enzymes [BR:
maf01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
MAF_24640 (folC)
6.3.2.17 tetrahydrofolate synthase
MAF_24640 (folC)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
CCC27534
LinkDB
All DBs
Position
complement(2734293..2735756)
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AA seq
487 aa
AA seq
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MNSTNSGPPDSGSATGVVPTPDEIASLLQVEHLLDQRWPETRIDPSLTRISALMDLLGSP
QRSYPSIHIAGTNGKTSVARMVDALVTALHRRTGRTTSPHLQSPVERISIDGKPISPAQY
VATYREIEPLVALIDQQSQASAGKGGPAMSKFEVLTAMAFAAFADAPVDVAVVEVGMGGR
WDATNVINAPVAVITPISIDHVDYLGADIAGIAGEKAGIITRAPDGSPDTVAVIGRQVPK
VMEVLLAESVRADASVAREDSEFAVLRRQIAVGGQVLQLQGLGGVYSDIYLPLHGEHQAH
NAVLALASVEAFFGAGAQRQLDGDAVRAGFAAVTSPGRLERMRSAPTVFIDAAHNPAGAS
ALAQTLAHEFDFRFLVGVLSVLGDKDVDGILAALEPVFDSVVVTHNGSPRALDVEALALA
AGERFGPDRVRTAENLRDAIDVATSLVDDAAADPDVAGDAFSRTGIVITGSVVTAGAART
LFGRDPQ
NT seq
1464 nt
NT seq
+upstream
nt +downstream
nt
atgaattcgacgaattccggcccgcctgactcgggatcggccaccggcgtcgtgcccact
ccggacgagatcgcgtccctgctgcaggttgagcatctactcgaccaacgctggccggag
acccgcatcgatccgagcctgacccggatcagcgcgttgatggacctgctgggctcgccc
caacgcagctatccgtcgatccatatcgcgggcaccaacggcaagacctcggtggcgcgc
atggtcgacgcgctggtcaccgcgctgcaccggcgcaccggccgaaccaccagcccacac
ctgcagtcaccggtggaacgcatttcgatcgacggcaagccgatcagcccggcgcagtat
gtggcgacctaccgggagatcgagccgttggtggcgctgatcgaccagcagtcgcaggct
tctgcgggtaagggtggcccggcgatgagcaagttcgaggtgctcaccgcgatggcgttc
gcggcctttgcggacgcgcccgtcgacgtggcagtggtcgaggtgggcatgggcggacgt
tgggacgccaccaacgtgatcaacgcaccggtcgccgtcatcaccccgatcagcattgat
cacgtcgactatctcggtgccgatatcgccgggatcgccggggagaaggcgggcatcatc
actcgggcccccgacggttcgccggacaccgtcgcggtcatcgggcgtcaggtcccgaag
gtcatggaggtgctgctggccgaatcggtgcgcgccgacgcgtcggtggcccgggaggat
tccgaattcgcggtgctacggcgacagatcgcggtcggcggtcaggtactgcaactgcag
ggcctcggcggggtttactccgacatctacttgccgctgcacggtgaacaccaggcgcac
aacgcggtgctcgccctcgcttccgtcgaggcctttttcggtgccggtgcgcagcgtcag
ctcgacggcgacgccgtccgggccggctttgccgccgtcaccagtcccggccggttggag
cgcatgcgcagcgcacccacggtgttcatcgacgccgcgcacaatccggccggggcgagt
gctctggcacaaacgctggcgcatgagttcgacttccgatttctggtcggggtgctcagc
gtgctgggcgacaaggacgtggacggcatcctggccgcactggagccggtgttcgattcc
gtcgtcgtgacccacaacgggtcgccgcgggcgctggatgtcgaggccctggcgctggcg
gccggcgagcggttcggacccgaccgggtgcgcaccgccgagaacctgcgcgatgctatc
gacgttgccacctcactggtcgacgacgccgccgccgacccggatgtggccggggacgca
ttctcgagaaccgggatcgtcatcaccggctcggttgtcaccgcaggggcggctcggacc
ttgttcggtcgtgatccgcaatga
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