Candidatus Methylopumilus planktonicus: BN1208_0710
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Entry
BN1208_0710 CDS
T03869
Symbol
folC
Name
(GenBank) bifunctional folylpolyglutamate synthase and dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
mbat
Candidatus Methylopumilus planktonicus
Pathway
mbat00790
Folate biosynthesis
mbat01100
Metabolic pathways
mbat01240
Biosynthesis of cofactors
Module
mbat_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
mbat00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
BN1208_0710 (folC)
Enzymes [BR:
mbat01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
BN1208_0710 (folC)
6.3.2.17 tetrahydrofolate synthase
BN1208_0710 (folC)
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
DUF2235
Motif
Other DBs
NCBI-ProteinID:
CEZ19596
UniProt:
A0A0D6EVR8
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Position
1:643006..644256
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AA seq
416 aa
AA seq
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MNLNDWIGYIESIHPSTIDLTLERIKIVIERLNLDVSFPILTVGGTNGKGSTCSILESIY
KEAGYKVACYTSPHFLHFNERIKIQAVAVSDELICEAFSRIESAREGVTLTYFEYGTIAA
MIIFSEAHVDVAILEVGLGGRLDAVNVFDADCAIVTTVDLDHMDYLGHTREAIGFEKAGI
YRTEKIAICGDFDPPQTLIKHAEFIHADLKIIGKDFGYEAHHDSFDFLIDSSFVINLPLP
KLQGDFQLANATNALMAVKAMEDKLPLTEISIQKGIALTLLPGRFQEVKKMPSLILDVAH
NPQAARSLSHNLETHVVPGKTIAVFSILKDKDISGVIKVLNLCIDAWFIAEIQNERAASI
ETISNAIQKINPSAHIEAFKNIQEAYQFASKEVTRNDRIIVFGSFFTVADIMKIIS
NT seq
1251 nt
NT seq
+upstream
nt +downstream
nt
atgaatcttaacgattggatagggtatatcgaatcaattcatccatccacgattgacctc
acactagagcgtatcaaaattgttatcgagcggttaaatttagacgtttctttccctatt
cttactgttggtggcacgaatggcaaaggctctacttgcagtattctagaatcgatatat
aaagaagctggttataaagtcgcttgctatacctcaccacattttttacattttaatgag
cgcattaaaattcaagcggttgctgtttcagatgagcttatttgtgaggcattttcaaga
attgaatcggcgagagaaggtgtaacacttacttacttcgaatacgggacaattgccgct
atgattattttttcagaggcccatgtagacgtagctattctagaagtaggtttaggaggc
agattagatgctgtaaatgtttttgatgctgattgtgccattgttacaactgttgatctt
gatcatatggattatttagggcacacaagagaagctattggattcgagaaagctggtatt
tatcgtactgaaaagattgccatttgtggcgacttcgatccgccgcaaactttaataaag
catgctgaatttattcatgctgatttaaaaattataggcaaagattttggttatgaagcc
catcatgattcgtttgattttttaattgattcatcatttgtaataaacttacccttgcct
aaattacaaggtgattttcagttagccaatgcaacaaatgcgcttatggcagttaaagct
atggaagataaattgcctttaactgaaatttcaattcaaaagggtattgcattgacttta
ttaccaggcagatttcaggaagtcaaaaaaatgccttctttgattttggatgtagctcac
aacccccaggctgcaagatctttaagccacaacctcgaaacacatgttgtgcccggtaaa
acaatagcagtattttcgatacttaaagacaaagatatttctggtgtgattaaggtatta
aacctctgcattgatgcgtggtttattgcagaaattcaaaacgagagagcagcaagtatt
gaaactatttctaatgctatccaaaaaattaatccatctgctcatatagaggcatttaag
aatatacaggaagcttatcaatttgcgtccaaggaagtcacgagaaatgatagaataatt
gtattcggttctttctttaccgttgcagatattatgaaaattatttcctaa
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