Mycolicibacterium boenickei: MBOE_02330
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Entry
MBOE_02330 CDS
T07414
Symbol
hemD
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
mbok
Mycolicibacterium boenickei
Pathway
mbok00860
Porphyrin metabolism
mbok01100
Metabolic pathways
mbok01110
Biosynthesis of secondary metabolites
mbok01120
Microbial metabolism in diverse environments
mbok01240
Biosynthesis of cofactors
Module
mbok_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
mbok_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
mbok00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
MBOE_02330 (hemD)
Enzymes [BR:
mbok01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
MBOE_02330 (hemD)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
MBOE_02330 (hemD)
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
BBX88584
UniProt:
A0A7I7MWD9
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Position
complement(240870..242561)
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AA seq
563 aa
AA seq
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MTMRGRKAKPGRITFVGSGPGDPGLLTARAQSVLAHAELVFTDPDVPAAVLALIGTDLPP
ASGPAPAAPAKADAAAGAASDGDAAANSDAAQAAVIAGGPEVRPALGDPAEVAKTLVAEA
RHGYDVVRLVAGDPLSVDAVITEIGALAKSHVNFEIVPGLPATSAVPTYAGLPLGSSHTV
ADVRGDVDWAALAAAPGPLILHATASHLPDAARTLIEQGLVDSTPAVVTASGTTCQQRSV
ETTLGGLIDKATLEKPAGSELAGPLTGPLVVTIGKTVANRAKLNWWESRALYGWTVLVPR
TKDQAGEMSEKLVGHGALPIEVPTIAVEPPRSPAQMERAVKGLVDGRFQWVVFTSTNAVR
AVWEKFNEFGLDARAFSGVKIACVGQATADKVRAFGINPELVPSGEQSSLGLLDEFPPFD
EVFDPVNRVLLPRADIATETLAEGLRERGWEIEDVTAYRTVRAAPPPAQTREMIKTGGFD
AVCFTSSSTVRNLVGIAGKPHARTIVACIGPKTAETAAEFGLRVDVQPESAAVGPLVDAL
AEHAARLRAEGALPPPRKKSRRR
NT seq
1692 nt
NT seq
+upstream
nt +downstream
nt
atgaccatgcgaggtcgcaaggcgaagcccggccgcatcacatttgtgggctcaggcccg
ggagatccggggctgctgacggcacgggcgcaatccgtgctggcgcacgccgagttggtg
ttcaccgatcccgacgtcccagcagccgtgttggccctgatcggcaccgacctgccgccg
gcctccggcccggccccggccgccccggccaaggccgacgctgctgccggtgccgcatcc
gacggcgacgccgccgccaactctgacgcggctcaggccgccgtcatcgccggcgggcct
gaagtgcgccccgctctcggcgaccccgccgaggtggccaagacgctggtcgccgaggcc
cgccacggctatgacgtggtccgcctggttgccggtgacccgctgtcggtcgacgctgtc
atcaccgagatcggcgcgctggccaagtcccacgtgaacttcgagatcgttcccggcctg
cccgccaccagcgcggtgcccacctacgcgggcctgccgctgggttcgtcgcacacggtg
gccgacgtccgcggtgacgtggactgggcggcgctggccgccgcgcccgggccgctgatc
ctgcacgcgaccgcgtcgcacctgccggacgccgcacgcaccctgatcgagcaggggctg
gtcgacagcaccccggccgtggtcaccgcgagcggcaccacctgccagcagcgctcggtg
gagaccaccctcggtggcctgatcgacaaggccacgctggagaagccggccggcagtgag
ctggccgggccgttgaccgggccgctggtcgtcaccatcggcaagacggtggccaaccgg
gccaagctgaactggtgggagagccgcgccctgtacggctggaccgtgctggtgccgcgt
accaaggatcaggccggcgagatgagcgagaagctcgtgggccacggcgcgctgccgatc
gaggtgccgaccatcgccgtcgagccgccgcgcagccccgcgcagatggagcgcgcggtc
aagggtctggtcgacggccggttccagtgggtggtgttcacctcgaccaacgccgtgcgt
gcggtgtgggagaagttcaacgagttcggcctggatgctcgggcgttctcgggcgtgaag
atcgcgtgcgtcggacaggccaccgccgacaaggtgcgggcgttcggcatcaaccccgag
ctggtgccgtccggggagcagtcctcgctcggcctgctcgacgagttcccgccgttcgac
gaggttttcgatccggtgaaccgcgtgctgctgccgcgtgccgacatcgccaccgagacg
ctggccgagggcctgcgcgaacgcggctgggagatcgaggatgtcaccgcctatcgcacc
gtgcgtgcggctccgccgccggcgcagacccgcgagatgatcaagaccggcgggttcgac
gcggtctgcttcacctcgagctcgaccgtgcgcaacctggtcggtatcgcgggcaagccg
cacgcccggaccatcgtggcctgcatcgggcccaagaccgctgaaaccgcagcggaattc
ggcctgcgggtggacgtgcagcccgagtcggccgcggtcggtccgctggtcgatgcgctg
gccgaacacgctgcccggctccgtgccgagggggcgctgcccccgccgcgcaagaagagc
cgccgcaggtaa
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