Mycolicibacterium brumae: L2Z93_002476
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Entry
L2Z93_002476 CDS
T08531
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
mbrm
Mycolicibacterium brumae
Pathway
mbrm00790
Folate biosynthesis
mbrm01100
Metabolic pathways
mbrm01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
mbrm00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
L2Z93_002476
Enzymes [BR:
mbrm01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
L2Z93_002476
6.3.2.17 tetrahydrofolate synthase
L2Z93_002476
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
UWW09380
LinkDB
All DBs
Position
complement(2554473..2555882)
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AA seq
469 aa
AA seq
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MSAAEPTPDEIAALLQVEHLLDQRWPETKIEPSLVRINALLELLGSPQRSYPTIHIAGTN
GKTSVARMVDALLTALHRRTGRTTSPHLQSAVERIAIDGVPISPAAYVETYTEIEPYVLM
VDEQSVSGALGEPGPAMSKFEVLTAMAFAAFADAPVDIAVVEVGLGGRWDATNVVDAPVA
VITPIGLDHQDYLGEDLAAIAGEKAGIITAAAEGPETVAVIARQAPEAMEVLLEQAIRAD
AAVAREDSEFAVLERRTAIGGQLLRLQGLGGVYEDIFLPLHGEHQAHNAVLALAAVEAFF
GAGAERQLDVDAVRAGFAAVRSPGRLERMRSAPTVFIDAAHNPAGATALAQTLAEEFDFH
HLVGVVSVMADKDCVGILAALEPVFDEAVVTHNGSPRAMGVDELALLAIDRFGPDRVHTA
PRLADAIETATALAEEAGAQTGLSGAGIVITGSVVTAGAARTLFGKDPA
NT seq
1410 nt
NT seq
+upstream
nt +downstream
nt
atgagcgccgccgaacccaccccggacgagatcgcggccctgctgcaggtcgagcacctg
ctggaccagcgctggccggagaccaagatcgagccgtcgctggtgcggatcaacgcgctg
ctggaactgctcggttcgccgcagcgcagctacccgacgatccacatcgccggcaccaac
ggcaagacctcggtcgcgcggatggtcgacgccctgctcaccgcgctgcaccggcgcacc
ggccgcaccaccagcccgcatctgcagtctgccgtggagcggatcgcgatcgacggcgtc
ccgatctccccggccgcgtatgtggagacctacaccgagatcgagccgtacgtgctgatg
gtcgacgagcagtcagtgtctggcgccctcggcgagcccgggccggcgatgagcaagttc
gaggtgctcaccgccatggcgttcgcggccttcgccgacgcgccggtggacatcgccgtc
gtcgaggtcggcctcggtgggcggtgggacgccaccaacgtcgtcgacgccccggtcgcg
gtgatcactcccatcggcctggaccaccaggactacctcggtgaggacctggcggccatc
gcgggggagaaggccgggatcatcaccgcggccgccgagggaccggagaccgtcgcggtg
atcgcccgacaggccccggaggcgatggaggtgctgctggagcaggcgatccgggccgac
gccgcggtggcgcgcgaggactcggagttcgcggtgctggagcggcgcaccgcgatcggc
ggccaactgctgcggctgcagggtctcggtggggtgtacgaagacatctttctgccgctg
cacggggagcaccaggcgcacaacgcggtcctggcgctggccgcagtggaggcgttcttc
ggcgccggcgccgagcggcaactcgacgtcgacgccgtgcgcgccggcttcgcggcggtc
cgcagcccgggccggttggaacggatgcgcagcgccccaacggttttcatcgacgccgcg
cacaacccggcgggcgccaccgcgctggcgcagaccctggccgaggagttcgacttccac
catctggtcggcgtggtgtcggtgatggcggataaggactgcgtcggcatcctggccgcg
ctggaaccggtgttcgacgaggccgtggtcacccacaacgggtcgccgcgggcgatgggc
gtcgacgaactggcgctgctggccatcgaccggttcggcccggatcgggtgcacaccgcg
ccgagactggccgacgccatcgaaaccgccaccgcgctggccgaggaagccggcgcgcag
accgggctgtccggggccggcatcgtgatcaccggatcggtcgtcaccgccggcgccgcg
cgcaccctgttcggaaaggacccggcgtga
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