Mus caroli (Ryukyu mouse): 110291389
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Entry
110291389 CDS
T05910
Symbol
Pdha2
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
mcal
Mus caroli (Ryukyu mouse)
Pathway
mcal00010
Glycolysis / Gluconeogenesis
mcal00020
Citrate cycle (TCA cycle)
mcal00620
Pyruvate metabolism
mcal00785
Lipoic acid metabolism
mcal01100
Metabolic pathways
mcal01200
Carbon metabolism
mcal01210
2-Oxocarboxylic acid metabolism
mcal04066
HIF-1 signaling pathway
mcal04922
Glucagon signaling pathway
mcal05230
Central carbon metabolism in cancer
mcal05415
Diabetic cardiomyopathy
Module
mcal_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
mcal00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
110291389 (Pdha2)
00020 Citrate cycle (TCA cycle)
110291389 (Pdha2)
00620 Pyruvate metabolism
110291389 (Pdha2)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
110291389 (Pdha2)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
110291389 (Pdha2)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
110291389 (Pdha2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
110291389 (Pdha2)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
110291389 (Pdha2)
Enzymes [BR:
mcal01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
110291389 (Pdha2)
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Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
110291389
NCBI-ProteinID:
XP_021014173
Ensembl:
MGP_CAROLIEiJ_G0025688
UniProt:
A0A6P5PAK4
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All DBs
Position
3:complement(134512161..134514030)
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AA seq
391 aa
AA seq
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MRKMLTAVLSHVFSGMVQKPALRGLLSSLKFSNDATCDIKKCDLYRLEEGPPTSTVLTRA
EALKYYRTMQVIRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLEAGINPTDHIITSYR
AHGLCYTRGLSVKSILAELTGRRGGCAKGKGGSMHMYGKNFYGGNGIVGAQVPLGAGVAF
ACKYLKNGQVCLALYGDGAANQGQVFEAYNMSALWKLPCVFICENNLYGMGTSNERAAAS
TDYHKKGFSIPGLRVNGMDILSVREATKFAADHCRSGKGPIVMELQTYRYHGHSMSDPGI
SYRSREEVHNVRSKSDPIMLLRERIISNNLSNIEELKEIDADVKKEVEEAAQFATTDPEP
AVEDIANYLYHQNPPFEVRGAHKWLKYKSHS
NT seq
1176 nt
NT seq
+upstream
nt +downstream
nt
atgaggaaaatgctgaccgctgtgctgtctcacgtattttcgggaatggtccaaaagcca
gctctcagaggactgctgtcatctctgaagttctccaacgacgccacctgtgacattaag
aaatgtgacctgtaccggctggaggagggcccaccgacctccaccgtgctcacccgagcc
gaggccctcaagtactatcggaccatgcaggtaattcggcgcatggagttgaaggccgac
cagctgtataagcagaaattcatccgtggtttctgtcacctgtgtgatgggcaggaagcc
tgctgtgtggggctggaggcagggataaatcccacggatcacatcatcacgtcctaccgg
gctcatggcttgtgctacacaaggggactgtccgtgaagtccattctcgcagagctgact
ggacgcagaggaggctgtgctaaaggcaagggaggctctatgcacatgtacggcaagaac
ttctacggtggcaatggcattgttggggcccaggtacccctgggagctggtgtggctttc
gcctgtaaatacctgaagaatggtcaggtctgcttggctttgtacggtgatggtgcggct
aaccaagggcaggtattcgaagcatacaatatgtcagccttgtggaaattaccctgtgtt
ttcatctgtgagaataacctctatggaatgggaacctccaatgagagagcagcagccagt
actgattaccacaagaaaggttttagtatccccggactgagggtgaatgggatggatatt
ctcagtgttcgggaggcaaccaagtttgcagctgatcactgcagatctggaaaggggccc
attgtgatggagctgcagacctaccgttatcatggacacagtatgagcgacccagggatc
agttatcgttcacgagaagaagttcataacgtgagaagtaagagtgatcctataatgctg
ctccgagagagaattatcagcaacaacctcagcaatattgaagaattgaaagaaattgat
gcagatgtgaagaaagaagtggaggaagcagctcagtttgctacaactgatccagaacca
gctgtggaagatatagctaattacctctaccaccaaaatccaccttttgaagtccgtggt
gcacataagtggctcaagtataagtcccacagttag
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