Macaca mulatta (rhesus monkey): 100423990
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Entry
100423990 CDS
T01028
Symbol
PDHA1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
mcc
Macaca mulatta (rhesus monkey)
Pathway
mcc00010
Glycolysis / Gluconeogenesis
mcc00020
Citrate cycle (TCA cycle)
mcc00620
Pyruvate metabolism
mcc00785
Lipoic acid metabolism
mcc01100
Metabolic pathways
mcc01200
Carbon metabolism
mcc01210
2-Oxocarboxylic acid metabolism
mcc04066
HIF-1 signaling pathway
mcc04922
Glucagon signaling pathway
mcc05230
Central carbon metabolism in cancer
mcc05415
Diabetic cardiomyopathy
Module
mcc_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
mcc00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
100423990 (PDHA1)
00020 Citrate cycle (TCA cycle)
100423990 (PDHA1)
00620 Pyruvate metabolism
100423990 (PDHA1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
100423990 (PDHA1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
100423990 (PDHA1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
100423990 (PDHA1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
100423990 (PDHA1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
100423990 (PDHA1)
Enzymes [BR:
mcc01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
100423990 (PDHA1)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
100423990
NCBI-ProteinID:
NP_001243768
Ensembl:
ENSMMUG00000017336
UniProt:
F7HBM4
LinkDB
All DBs
Position
X:19100547..19118719
Genome browser
AA seq
390 aa
AA seq
DB search
MRKMLAAVSRVLSGASQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTRED
GLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRA
HGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALA
CKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAAST
DYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVS
YRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPP
LEELGYHIYSSDPPFEVRGANQWIKFKSVS
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagatgctcgccgccgtctcccgcgtgttgtctggcgcttctcagaagccggca
agcagagtgctggtagcatcccgtaattttgcaaatgatgctacatttgaaattaagaaa
tgtgaccttcaccgactggaagaaggccctcctgtcacaacagtgctcaccagggaggat
gggctcaaatactacaggatgatgcagactgtgcgccgaatggagttgaaagcagatcag
ctgtataaacagaaaattattcgtggtttctgtcacttgtgtgatggtcaggaagcttgc
tgtgtgggcctggaagccggcatcaaccccacagaccatctcataacagcctaccgggct
catggctttaccttcacccggggcctttccgtccgagaaattctcgcagagcttacagga
cgaaaaggaggttgtgctaaagggaaaggaggatcgatgcacatgtatgccaagaacttc
tacgggggcaatggcatcgtgggagcgcaggtgcccctgggcgctgggattgctctagcc
tgtaagtataatggaaaagatgaggtctgcctgactttatatggcgatggtgctgctaac
cagggccagatatttgaagcttacaacatggcagctttgtggaaattaccttgtattttc
atctgtgagaataatcgctatggaatgggaacatctgttgagagagcagcagccagcact
gattactacaagagaggcgatttcattcctgggctgagagtggatggaatggatatcttg
tgcgtccgagaggcgacaaggtttgctgccgcctattgtagatctgggaaggggcccatc
ctgatggagctgcagacttatcgttaccacggacacagtatgagtgatcctggagtcagt
taccgtacacgagaagaaattcaggaagtaagaagtaagagtgaccctattatgcttctc
aaggacaggatggtgaacagcaatcttgccagtgtggaagaactaaaggaaattgatgtg
gaagtgaggaaggagattgaggatgctgcccagtttgccacagccgatcctgagccacct
ttggaggagctgggctaccacatctactccagcgacccacctttcgaagttcgtggtgcc
aatcagtggatcaagtttaagtcagtcagttaa
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