Macaca mulatta (rhesus monkey): 709359
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Entry
709359 CDS
T01028
Symbol
PDHA2
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
mcc
Macaca mulatta (rhesus monkey)
Pathway
mcc00010
Glycolysis / Gluconeogenesis
mcc00020
Citrate cycle (TCA cycle)
mcc00620
Pyruvate metabolism
mcc00785
Lipoic acid metabolism
mcc01100
Metabolic pathways
mcc01200
Carbon metabolism
mcc01210
2-Oxocarboxylic acid metabolism
mcc04066
HIF-1 signaling pathway
mcc04922
Glucagon signaling pathway
mcc05230
Central carbon metabolism in cancer
mcc05415
Diabetic cardiomyopathy
Module
mcc_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
mcc00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
709359 (PDHA2)
00020 Citrate cycle (TCA cycle)
709359 (PDHA2)
00620 Pyruvate metabolism
709359 (PDHA2)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
709359 (PDHA2)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
709359 (PDHA2)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
709359 (PDHA2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
709359 (PDHA2)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
709359 (PDHA2)
Enzymes [BR:
mcc01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
709359 (PDHA2)
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Motif
Pfam:
E1_dh
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
709359
NCBI-ProteinID:
XP_001097880
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Position
5:94194389..94195798
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AA seq
391 aa
AA seq
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MKKMLAVFISRVLRRVAQKSARRVLVASRNSSNDATFEIEKCDLHLLEEGPPVTTVLTRA
EGLKYYRMMLTVRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLEAGINPSDHLITSYR
AHGMCYTRGLSVRSILTELTGRRGGCAKGKGGSMHMYTKNFYGGNGIVGAQGPLGAGIAL
ACKYKGNNEICLTLYGDGAANQGQIAEAFNMAALWKLPCVFICENNLYAMGTSAERAAAS
TDYYKRGNFIPGLKVDGMDVLCVREATKFAADYCRSGKGPILMELQTYRYHGHSMSDPGV
SYRTRDEIQEVRSKRDPIMILQDRMVNSKLATVEELKEIGTEVKKEIDDAAQFAISDPEP
RLEELGHHIYSSDSSFEVRGANPWIKFKSVS
NT seq
1176 nt
NT seq
+upstream
nt +downstream
nt
atgaagaaaatgctggccgtcttcatctcccgcgtgttgaggcgagttgcccagaagtca
gctcgcagagtgctggtggcatcccgtaactcctcaaatgacgctacatttgaaattgag
aaatgtgatcttcacctgttggaggagggtccccccgtcactacagtgctcactagggcg
gaggggcttaaatactacaggatgatgctgactgttcgccgcatggaattgaaggcagat
cagctgtacaaacagaaattcattcgtggtttctgtcacctgtgcgatggtcaggaagct
tgctgcgtgggccttgaggctggaataaacccctcggatcacctcatcacatcctatagg
gctcatggtatgtgctatactcggggactttctgtccgatccattctcacagagctgacg
ggaagaagaggaggttgtgctaaaggaaaaggaggatcgatgcatatgtataccaagaac
ttctacgggggcaatggcatcgtcggcgcgcagggccccctgggcgctggcattgctctg
gcctgtaaatataagggaaacaatgagatctgtttgactttatatggcgatggcgctgcg
aatcaggggcagatagccgaagctttcaatatggcagctttatggaaattaccttgtgtt
ttcatctgtgagaataacctatatgcaatgggaacatctgctgagagagcagcagccagc
actgattactacaagaggggcaattttattcctgggctaaaagtcgatggaatggatgtt
ctatgtgttcgtgaggcaacaaaatttgcagctgactactgtaggtctggaaaggggccc
atactgatggagctgcagacctaccgttatcatggacacagtatgagtgatcctggagtc
agttatcgtacacgagatgaaattcaggaagtaagaagtaagagggatcctataatgatt
ctccaagatagaatggtaaacagcaagcttgccactgtggaagaattaaaggaaattggg
actgaggtgaagaaagaaattgatgatgctgcccaatttgctatcagtgatcctgagcca
cgtctggaagaattaggccatcacatctacagcagtgattcatcttttgaagttcgtggt
gcaaatccatggatcaagtttaagtccgtcagttaa
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