Macaca mulatta (rhesus monkey): 721610
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Entry
721610 CDS
T01028
Symbol
TPO
Name
(RefSeq) thyroid peroxidase
KO
K00431
thyroid peroxidase [EC:
1.11.1.8
]
Organism
mcc
Macaca mulatta (rhesus monkey)
Pathway
mcc00350
Tyrosine metabolism
mcc01100
Metabolic pathways
mcc04918
Thyroid hormone synthesis
mcc05320
Autoimmune thyroid disease
Module
mcc_M00043
Thyroid hormone biosynthesis, tyrosine => triiodothyronine/thyroxine
Brite
KEGG Orthology (KO) [BR:
mcc00001
]
09100 Metabolism
09105 Amino acid metabolism
00350 Tyrosine metabolism
721610 (TPO)
09150 Organismal Systems
09152 Endocrine system
04918 Thyroid hormone synthesis
721610 (TPO)
09160 Human Diseases
09163 Immune disease
05320 Autoimmune thyroid disease
721610 (TPO)
Enzymes [BR:
mcc01000
]
1. Oxidoreductases
1.11 Acting on a peroxide as acceptor
1.11.1 Peroxidases
1.11.1.8 iodide peroxidase
721610 (TPO)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
An_peroxidase
EGF_CA
EGF_3
Sushi
FXa_inhibition
cEGF
EGF
Motif
Other DBs
NCBI-GeneID:
721610
NCBI-ProteinID:
XP_028687879
Ensembl:
ENSMMUG00000009662
LinkDB
All DBs
Position
13:complement(107243278..107349164)
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AA seq
1053 aa
AA seq
DB search
MEMGFGRVVEVLDSEEDLHAIPPSAKSCANFSLERSCQVTLPLGEKAAPGEGVRCVTRRL
ICLTPELMAVTPLPPKNAGNIPKAPESWGVVTVFGKQLHAGGWTLLHSKEVKARGGEASR
RPGRLPALETTWASPQPDGLERQSNTVSESPNRKPEESRVAGVLEESKRLVDTAMYATMQ
RNLKKREILSPHQLLSFSKLPEPTSGEIARAAEIMETSIQAMKRKVNLKIQQSQHPTDAL
SEDLLSIIANMSGCLPYMLPPKCPNTCLANKYRLITGACNNRDHPRWGASNTALARWLPP
VYEDGFSQPRGWNPSILHNGFPLPPVREVTRHVIQVSNEVVTDDDRYSDLLMAWGQYIDH
DIAFTPQSTSKAAFRGGADCQVTCENQNPCFPIQLPEEARPAAGTACLPFYRSSAACGTG
DQGALFGNLSTANPRQQMNGLTSFLDASTVYGSSPALERQLRNWTSAEGLLRVHARLRDS
GRAYLPFAPPRAPAACAPEPGIPGETRGPCFLAGDGRASEVPSLTALHTLWLREHNRLAA
ALKALNAHWSADAVYQEARKVVGALHQIITLRDYVPRILGPEAFQQYVGPYEGYDSAANP
TVSNVFSTAAFRFGHATIHPLVRRLDAGFQEHPGLPGLWLHETFFSPWTLLHGGGLDPLI
RGLLARPAKLQVQDQLMNEELTERLFVLSNSSTLDLASINLQRGRDHGLPGYNEWREFCG
LPRLETPADLSTAIASRSVADKILDLYKHPDNIDVWLGGLAENFLPRARTGPLFACLIGK
QMKALRDGDWFWWENSHVFTDAQRHELEKHSLSRVICDNTGLTRVPVDAFRVGKFPEDFE
SCDSIPGMNLEAWRETFPQDDKCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGHEQ
LTCTQEGWDFQPPLCKDVNECADGAHPPCHTSARCRNTKGGFQCLCADPYELGGDGRTCV
DSGRLPRATWVSISLAALLIGGLAGLTSTVICRWTRAGTKPTLPISETGGGTPRLRCGKH
WGAGTSQGAAAQDSEQESAGMEGRDTHRLPRAL
NT seq
3162 nt
NT seq
+upstream
nt +downstream
nt
atggagatgggttttgggcgggttgtggaagtcctggattctgaggaggacctgcatgca
attccgccctcagccaagagctgtgcaaacttctctctagaacgatcctgccaggtaact
ctgccgctaggagagaaagctgcgccaggtgaaggggtccgctgcgtcactcggagattg
atttgtctcactccagagctcatggccgtcacccctctgccacctaagaatgccggcaac
atcccaaaagcaccagagtcctggggggtggttactgtgtttggcaagcagcttcatgca
gggggatggacacttctccatagcaaggaagtgaaggcccgtggaggagaagcctcccgc
agacctggtcgcctgcctgccctggaaaccacgtgggcatcaccacagccagatgggctt
gagcgacaaagcaacaccgtcagtgaatccccgaaccgaaagcctgaggagtctcgtgtc
gccggcgtcttggaggaaagcaagcggctggtggacactgccatgtacgccacgatgcag
agaaacctcaaaaaaagagaaatcctttccccacatcagcttctgtctttttccaaactt
cccgagccaactagcggagagattgcccgagcagcagagataatggaaacatcaatacaa
gcgatgaaaagaaaagtcaacctgaaaattcaacaatcacagcatccaaccgatgcttta
tcagaagatctgctgagcatcattgcaaacatgtccgggtgtctcccttacatgctgccc
ccaaaatgcccaaacacgtgcctggcgaacaaatacagactcatcacaggagcttgcaac
aacagagaccaccccagatggggtgcctccaacacagccctggcacgatggctccctcca
gtctacgaggacggcttcagtcagccccgaggctggaaccccagcatcttgcacaacggg
ttcccactgcccccggtccgggaggtgacacgacatgtcattcaagtttcaaatgaggtt
gtcacagatgatgaccgctattctgacctcctgatggcatggggacaatacatcgaccat
gacatcgcgttcacaccgcagagcaccagcaaagctgccttcaggggaggggctgactgc
caggtgacttgtgagaaccaaaacccatgttttcccatacaactcccggaggaggcccgg
ccggccgcgggcaccgcctgtctgcccttctaccgctcttcggccgcctgtggcaccggg
gaccaaggcgcgctcttcgggaacctgtccaccgccaacccgcggcagcagatgaacggg
ctgacctcgttcctggacgcgtccaccgtgtacggcagctccccggccctggagaggcag
ctgcggaactggaccagcgccgaggggctgctccgcgtccacgcgcgcctccgggactcc
ggccgcgcctacctgcccttcgcgccgccacgcgcgcccgcggcctgtgcgcctgagccc
ggcatccccggagagacccgcgggccctgcttcctggccggggacggccgcgccagcgag
gtcccctccctgacggcgctgcacacgctgtggctgcgcgagcacaaccgcctggccgcg
gcgctcaaggccctcaacgcgcactggagcgcggacgccgtgtaccaggaggcgcgcaag
gtcgtgggcgccctgcaccagatcatcaccctgagggattacgtccccaggatcctggga
cccgaggccttccagcagtacgtgggcccctatgaaggctatgactccgccgccaacccc
actgtgtccaacgtgttctccacggccgccttccgcttcggccacgccacgatccacccg
ctggtgaggaggctggacgctggcttccaggagcaccccggcctgcccgggctgtggctg
cacgagaccttcttcagcccatggacgctcctccacggaggtggtttggacccactaata
cgaggccttcttgcaagaccagccaaactgcaggtgcaggatcagctgatgaacgaggaa
ctgacggaaaggctctttgtgctgtccaattccagcaccttggatctggcgtccatcaac
ctgcagaggggccgggaccacgggctgccaggttacaacgagtggagggagttctgtggc
ctgcctcgcctggagacccccgctgacctgagcacagccatcgccagcaggagcgtggcc
gacaagatcctggacttgtacaagcatcctgacaacatcgacgtctggctgggaggctta
gctgaaaacttcctccccagggctcggacaggccccctgtttgcctgtctcattgggaag
cagatgaaggctctgcgggacggagactggttttggtgggagaacagccacgtcttcacg
gacgcgcagaggcatgagctggagaagcactccctgtctcgggtcatctgtgacaacacc
ggcctcaccagggtgcccgtggacgccttccgagtcggaaaattccctgaagactttgag
tcttgtgacagcatccctggcatgaacctggaggcctggagggagacctttcctcaagac
gacaagtgtggcttcccagagagcgtggagaatggggactttgtgcactgtgaggagtct
gggaggcgcgtgctggtgtattcctgccggcacgggtatgagctccaaggccacgagcaa
ctcacttgcacccaggaaggatgggatttccagcctccgctctgcaaagatgtgaacgag
tgtgcagacggtgcccacccaccctgccacacctctgcgaggtgcagaaataccaagggc
ggcttccagtgcctctgcgcggacccctacgagttaggaggcgatgggagaacctgcgta
gactccgggaggctccctcgggcgacttgggtctccatctcactggctgctctgctgatt
ggaggcttggcaggtctcacctcgacggtgatttgcaggtggacacgcgctggcactaaa
cccacactgcccatctcggagacaggcggaggaactccccggctgagatgcgggaagcac
tggggtgcagggacttcgcagggcgccgcagctcaggactcggagcaggagagtgccggg
atggaaggccgggatactcacaggctgccgagagccctctga
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