KEGG   Macaca fascicularis (crab-eating macaque): 102124167
Entry
102124167         CDS       T02918                                 
Symbol
TPH2
Name
(RefSeq) tryptophan 5-hydroxylase 2
  KO
K00502  tryptophan 5-monooxygenase [EC:1.14.16.4]
Organism
mcf  Macaca fascicularis (crab-eating macaque)
Pathway
mcf00380  Tryptophan metabolism
mcf00790  Folate biosynthesis
mcf01100  Metabolic pathways
mcf04726  Serotonergic synapse
Module
mcf_M00037  Melatonin biosynthesis, animals, tryptophan => serotonin => melatonin
Brite
KEGG Orthology (KO) [BR:mcf00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00380 Tryptophan metabolism
    102124167 (TPH2)
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    102124167 (TPH2)
 09150 Organismal Systems
  09156 Nervous system
   04726 Serotonergic synapse
    102124167 (TPH2)
Enzymes [BR:mcf01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.16  With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.16.4  tryptophan 5-monooxygenase
     102124167 (TPH2)
SSDB
Motif
Pfam: Biopterin_H TH_ACT ACT
Other DBs
NCBI-GeneID: 102124167
NCBI-ProteinID: XP_005571609
Ensembl: ENSMFAG00000035804
UniProt: A0A2K5VAQ7
LinkDB
Position
11:join(78758173..78758277,78760768..78760917,78763591..78763774,78763883..78763983,78769830..78769897,78789260..78789456,78796062..78796197,78811538..78811664,78839574..78839669,78848350..78848483,78848610..78848784)
AA seq 490 aa
MQPAMMMFSSKYWARRGFSLDSAVPEEHQLLGNLTLNKANSGKNDDKGNKGSSKNETATE
SGKTAVVFSLKNEVGGLVKALRLFQEKRVHMVHIESRKSRRRSSEVEIFVDCECGKTEFN
ELIQLLKFQTTIVTLNPPENIWTEEEELEDVPWFPRKISELDKCSHRVLMYGSELDADHP
GFKDNVYRQRRKYFVDVAMGYKYGQPIPRVEYTEEETKTWGVVFRELSKLYPTHACREYL
KNFPLLTKYCGYREDNVPQLEDVSVFLKERSGFTVRPVAGYLSPRDFLAGLAYRVFHCTQ
YIRHGSDPLYTPEPDTCHELLGHVPLLADPKFAQFSQEIGLASLGASDEDVQKLATCYFF
TIEFGLCKQEGQLRAYGAGLLSSIGELKHALSDKACVKAFDPKTTCLQECLITTFQEAYF
VSESFEEAKEKMRDFAKSITRPFSVYFNPYTQSIEILKDTRSIENVVQDLRSDLNTVCDA
LNKMNQYLGI
NT seq 1473 nt   +upstreamnt  +downstreamnt
atgcagccagcaatgatgatgttttccagtaaatactgggcaaggagagggttttccctg
gattcagcagtgcccgaagagcatcagctactcggcaacttaacactaaataaagctaac
tctggcaaaaatgacgacaaaggcaacaagggaagcagcaaaaatgaaactgctaccgaa
agtggcaagacagcagttgttttctccttgaaaaatgaagtcggtggattggtgaaagca
ctgaggctctttcaggaaaaacgcgtccacatggttcatattgaatccaggaaatctcgg
cgaaggagctctgaggttgaaatctttgtggactgtgagtgtgggaaaacagaattcaat
gagctcattcagttgctgaaatttcaaaccactattgtgacgctgaatcctccagagaat
atttggacagaggaagaagagctagaggatgtgccctggttccctcggaagatctctgag
ttagacaaatgctctcacagagttctcatgtatggttctgagcttgatgccgaccaccca
ggatttaaggacaatgtctatcgacagagaagaaagtattttgtggatgtggccatgggt
tataaatatggtcagcccattcccagggtggagtatactgaagaagaaactaaaacttgg
ggcgttgtattccgggagctctccaaactctatcccactcatgcttgccgagagtatttg
aaaaacttccctctgctgactaaatactgtggctacagagaggacaatgtgcctcaactc
gaagatgtctccgtgtttctgaaagaaaggtctggcttcaccgtgaggccggtggctgga
tacctgagcccacgagactttctggcaggactggcctacagagtgttccactgtacccag
tacatccggcatggctcagatcccctctacaccccggaaccagatacatgccatgaactc
ttgggacatgttccactacttgcggatcctaagtttgctcagttttcacaagaaataggt
ctggcgtctctgggagcatcagatgaagatgttcagaaactagccacgtgctatttcttc
acaatcgagtttggtctttgcaagcaagaagggcaactgcgggcatatggagcaggactc
ctttcctccattggagaattaaagcatgccctttctgacaaggcatgtgtgaaagccttt
gacccaaagacaacttgcttacaggaatgccttatcaccaccttccaggaagcctacttt
gtttcagaaagttttgaagaagccaaagaaaagatgagggactttgcaaagtcaattacc
cgtcccttctcagtatacttcaatccctacacgcagagtattgaaattctgaaagacacc
agaagtattgaaaatgtggtgcaggaccttcgcagcgacttgaacacagtgtgtgatgcc
ttaaacaaaatgaaccaatatctggggatttga

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