Macaca fascicularis (crab-eating macaque): 102125852
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Entry
102125852 CDS
T02918
Symbol
PDHA1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
mcf
Macaca fascicularis (crab-eating macaque)
Pathway
mcf00010
Glycolysis / Gluconeogenesis
mcf00020
Citrate cycle (TCA cycle)
mcf00620
Pyruvate metabolism
mcf00785
Lipoic acid metabolism
mcf01100
Metabolic pathways
mcf01200
Carbon metabolism
mcf01210
2-Oxocarboxylic acid metabolism
mcf04066
HIF-1 signaling pathway
mcf04922
Glucagon signaling pathway
mcf05230
Central carbon metabolism in cancer
mcf05415
Diabetic cardiomyopathy
Module
mcf_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
mcf00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
102125852 (PDHA1)
00020 Citrate cycle (TCA cycle)
102125852 (PDHA1)
00620 Pyruvate metabolism
102125852 (PDHA1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
102125852 (PDHA1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
102125852 (PDHA1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
102125852 (PDHA1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
102125852 (PDHA1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
102125852 (PDHA1)
Enzymes [BR:
mcf01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
102125852 (PDHA1)
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
102125852
NCBI-ProteinID:
XP_045240247
Ensembl:
ENSMFAG00000043170
LinkDB
All DBs
Position
X:18815087..18831397
Genome browser
AA seq
390 aa
AA seq
DB search
MRKMLAAVSRVLSGASQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTRED
GLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRA
HGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALA
CKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAAST
DYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVS
YRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPP
LEELGYHIYSSDPPFEVRGANQWIKFKSVS
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagatgctcgccgccgtctcccgcgtgttgtctggcgcttctcagaagccggca
agcagagtgctggtagcatcccgtaattttgcaaatgatgctacatttgaaattaagaaa
tgtgaccttcaccgactggaagaaggccctcctgtcacaacagtgctcaccagggaggat
gggctcaaatactacaggatgatgcagactgtgcgccgaatggagttgaaagcagatcag
ctgtataaacagaaaattattcgtggtttctgtcacttgtgtgatggtcaggaagcttgc
tgtgtgggcctggaagccggcatcaaccccacagaccatctcataacagcctaccgggct
catggctttaccttcacccggggcctttccgtccgagaaattctcgcagagcttacagga
cgaaaaggaggttgtgctaaagggaaaggaggatcgatgcacatgtatgccaagaacttc
tacgggggcaatggcatcgtgggagcgcaggtgcccctgggcgctgggattgctctagcc
tgtaagtataatggaaaagatgaggtctgcctgactttatatggcgatggtgctgctaac
cagggccagatatttgaagcttacaacatggcagctttgtggaaattaccttgtattttc
atctgtgagaataatcgctatggaatgggaacatctgttgagagagcagcagccagcact
gattactacaagagaggcgatttcattcctgggctgagagtggatggaatggatatcttg
tgcgtccgagaggcgacaaggtttgctgccgcctattgtagatctgggaaggggcccatc
ctgatggagctgcagacttatcgttaccacggacacagtatgagtgatcctggagttagt
taccgtacacgagaagaaattcaggaagtaagaagtaagagtgaccctattatgcttctc
aaggacaggatggtgaacagcaatcttgccagtgtggaagaactaaaggaaattgatgtg
gaagtgaggaaggagattgaggatgctgcccagtttgccacggccgatcctgagccacct
ttggaggagctgggctaccacatctactccagcgacccacctttcgaagttcgtggtgcc
aatcagtggatcaagtttaagtcagtcagttaa
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