Micromonospora chalcea: PVK74_15650
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Entry
PVK74_15650 CDS
T08919
Name
(GenBank) thiamine pyrophosphate-dependent enzyme
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
mchl
Micromonospora chalcea
Pathway
mchl00280
Valine, leucine and isoleucine degradation
mchl00640
Propanoate metabolism
mchl00785
Lipoic acid metabolism
mchl01100
Metabolic pathways
mchl01110
Biosynthesis of secondary metabolites
mchl01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
mchl00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
PVK74_15650
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
PVK74_15650
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
PVK74_15650
Enzymes [BR:
mchl01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
PVK74_15650
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Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Transketolase_N
Motif
Other DBs
NCBI-ProteinID:
WDP97361
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Position
3603041..3604171
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AA seq
376 aa
AA seq
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MTTVDLADSPVTNPFTGTTDLPRAAEGWTQLVTPDGRLHPDVDVDRDALGHLTRDLYRGM
RLARRLDDEAFALQRQGELGLWLQCRGQEAAQVGSVAAVRADDYVFPSYREHAAALWRGI
GPADLLRQWRGVAHSGWDPEPYSFHIYTLVLAAQLLHATGYALGVQRDGSDTVVVTYFGD
GAASEGDASEAMNIAAVNAAPMVFFCQNNQWAISTPTASQTRTPIHRRGAGFGLRSEWVD
GNDVLAVYAVTSAVTEHARAGAGPAIVEATTYRMGGHSTSDDPTRYRTDDELEAWRARDP
LARVEALMRAEGWSDETFLGQIQAEADELADRTRRECLALTAPDLADAFATVLSDVPQLL
REERDAFVAYRGSFLD
NT seq
1131 nt
NT seq
+upstream
nt +downstream
nt
atgactaccgtagatctcgccgactcaccggtcaccaaccccttcaccggcaccaccgac
cttccgcgcgccgccgagggctggacccagctcgtcaccccggacggacgcctgcacccg
gacgtggacgtcgaccgagacgccctcggccacctcacccgcgacctgtaccgggggatg
cggctggcccgccgcctcgacgacgaggcgttcgcgttgcagcgacagggcgagctgggc
ctgtggctgcagtgccgcggccaggaggccgcacaggtcggctccgtcgcggcggtacgc
gccgacgactacgtcttcccgagctaccgcgagcacgcggcggcgctgtggcgcggcatc
ggcccggccgacctgctccggcagtggcgcggcgtcgcgcacagcggctgggacccggag
ccgtactcgttccacatctacacgctggtgctggccgcgcagctgctgcacgccaccggg
tacgcgctcggcgtgcagcgcgacggcagcgacacggtggtagtgacgtacttcggtgac
ggcgcggccagtgagggcgacgcgagcgaggcaatgaacatcgccgccgtgaacgccgcc
ccgatggtgttcttctgccagaacaaccagtgggccatctccacgccgaccgcgtcgcag
acgcgtaccccgatccaccggcgcggcgccgggttcggcctgcgcagcgagtgggtcgac
ggcaacgacgtgctggcggtgtacgcggtgacgtcggcggtgaccgagcacgcccgcgcc
ggcgccggccccgcgatcgtcgaggccaccacgtaccggatgggcgggcacagcacgtcc
gacgacccgacccggtaccgcaccgacgacgagttggaagcctggcgggcgcgggacccg
ctggcccgggtcgaggcgctgatgcgcgccgagggctggagcgacgagacgttcctcggc
cagatccaggccgaggcggacgaactcgccgaccggacccgccgggagtgcctggccctg
acggccccggacctcgcggacgccttcgccacggtgctgtccgacgtgccccagcttctg
cgggaggagcgcgacgcgttcgtcgcctaccgcggctccttcctcgactga
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