Mastomys coucha (southern multimammate mouse): 116099600
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Entry
116099600 CDS
T07224
Symbol
Pdha1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
mcoc
Mastomys coucha (southern multimammate mouse)
Pathway
mcoc00010
Glycolysis / Gluconeogenesis
mcoc00020
Citrate cycle (TCA cycle)
mcoc00620
Pyruvate metabolism
mcoc00785
Lipoic acid metabolism
mcoc01100
Metabolic pathways
mcoc01200
Carbon metabolism
mcoc01210
2-Oxocarboxylic acid metabolism
mcoc04066
HIF-1 signaling pathway
mcoc04922
Glucagon signaling pathway
mcoc05230
Central carbon metabolism in cancer
mcoc05415
Diabetic cardiomyopathy
Module
mcoc_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
mcoc00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
116099600 (Pdha1)
00020 Citrate cycle (TCA cycle)
116099600 (Pdha1)
00620 Pyruvate metabolism
116099600 (Pdha1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
116099600 (Pdha1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
116099600 (Pdha1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
116099600 (Pdha1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
116099600 (Pdha1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
116099600 (Pdha1)
Enzymes [BR:
mcoc01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
116099600 (Pdha1)
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GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
116099600
NCBI-ProteinID:
XP_031239335
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All DBs
Position
X
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AA seq
358 aa
AA seq
DB search
MRKMLAAVSRVLAGAAQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTRED
GLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRA
HGFTFTRGLPVRAILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALA
CKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAAST
DYYKRGDFIPGLRVDGMDILCVREATKFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVS
YRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPE
NT seq
1074 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagatgcttgccgctgtgtcccgcgtgttggcaggcgctgcacagaagccggca
agcagagtgctggtagcttcccgtaattttgcaaatgatgctacatttgagattaagaaa
tgtgaccttcatcggctagaagagggccctccagtcaccacggtgctcaccagagaggat
gggctcaagtattacaggatgatgcagactgtgcgccggatggagctaaaggcagatcag
ctgtataagcagaaaattattcgtggtttctgtcacttatgtgatggtcaggaagcctgc
tgtgtaggcctggaggctggcataaaccccacggaccatctcatcactgcctatcgagca
catggtttcaccttcactaggggcctgcctgtccgagcaattcttgcggagctaacagga
cgaagaggaggttgtgctaaagggaaaggcggatcaatgcacatgtatgccaagaacttc
tatgggggcaatggcatcgttggagctcaggtgcccctgggagcaggaattgctctggcc
tgcaagtacaatggaaaagatgaggtctgtttgacattgtatggtgatggtgctgctaat
cagggtcagatctttgaagcttacaatatggcagcattgtggaaattaccttgtattttc
atctgtgagaataaccgctatggcatggggacatcggtcgagagagcagcagccagcaca
gactactacaaaagaggagattttattcctggactcagggtagatggaatggatatcttg
tgtgtccgagaggcaacaaagtttgcagctgcctattgcaggtctggtaaggggcccatc
ctgatggagctacagacttaccgctaccatggacatagcatgagtgaccctggagtaagt
taccgcactcgagaggaaatccaggaagtaagaagtaagagcgaccctattatgcttctc
aaggataggatggtgaacagcaatcttgcaagtgttgaagaattaaaggagattgatgtg
gaagtgaggaaagaaatcgaggatgctgcccagtttgccacggctgatccagag
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