Monodelphis domestica (gray short-tailed opossum): 100014220
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Entry
100014220 CDS
T01031
Symbol
PDHA1
Name
(RefSeq) pyruvate dehydrogenase (lipoamide) alpha 1
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
mdo
Monodelphis domestica (gray short-tailed opossum)
Pathway
mdo00010
Glycolysis / Gluconeogenesis
mdo00020
Citrate cycle (TCA cycle)
mdo00620
Pyruvate metabolism
mdo00785
Lipoic acid metabolism
mdo01100
Metabolic pathways
mdo01200
Carbon metabolism
mdo01210
2-Oxocarboxylic acid metabolism
mdo04066
HIF-1 signaling pathway
mdo04922
Glucagon signaling pathway
mdo05230
Central carbon metabolism in cancer
mdo05415
Diabetic cardiomyopathy
Module
mdo_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
mdo00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
100014220 (PDHA1)
00020 Citrate cycle (TCA cycle)
100014220 (PDHA1)
00620 Pyruvate metabolism
100014220 (PDHA1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
100014220 (PDHA1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
100014220 (PDHA1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
100014220 (PDHA1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
100014220 (PDHA1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
100014220 (PDHA1)
Enzymes [BR:
mdo01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
100014220 (PDHA1)
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
100014220
NCBI-ProteinID:
XP_007493545
Ensembl:
ENSMODG00000009055
UniProt:
A0A5F8GC60
LinkDB
All DBs
Position
4:complement(49747857..49772989)
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AA seq
395 aa
AA seq
DB search
MRKMLAVVSRVLTAVSQKPGAATETGRVLLATRNFANDASFDIKKCDIHRLEEGPPTTTI
LTREEGLKYYKIMQTVRRMELKADQLYKQKIIRGFCHLYDGQEACCVGLEAGINPSDHVI
TAYRAHGFTYTRGLTVREILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGA
GIALACKYNGKDEICLTLYGDGAANQGQIFETYNMAALWKLPCIFICENNRYGMGTSVER
AAASTDYYKRGDYIPGIRVDGMDVLCVREATKFAAAYCRSGKGPMVMELQTYRYHGHSMS
DPGVSYRTREEIQEVRSKSDPIMLLKDRMVNNNLASIEELKEIDVEVRKEIEDAAQFATA
DPEPPLEELGYHIYSREPPFEVRGANQWIKYKSIS
NT seq
1188 nt
NT seq
+upstream
nt +downstream
nt
atgaggaaaatgctcgccgtcgtttctcgcgtgctgacagccgtctcccagaaaccggga
gctgctactgagactggaagagtgctattggcaacccgtaactttgcaaatgatgcttca
tttgatattaagaaatgtgacattcatcgccttgaggagggccctcccaccacaacaatt
cttactagagaggaaggtctcaagtactataagataatgcagactgtccgtcggatggaa
ttgaaagcagaccagctgtataagcaaaaaatcatccgtggtttctgccacttgtatgat
ggtcaggaagcttgttgtgtggggcttgaggctggtataaatccttcagatcatgtgatt
acagcctatcgagctcatggctttacttatactcgtggacttaccgttcgagaaattctg
gcagagcttacaggacgaagagggggctgtgctaaaggaaagggaggatcaatgcacatg
tatgccaagaacttctatgggggcaatggcattgttggagctcaggtacctctaggagct
ggtattgccctggcctgcaagtacaatggaaaagatgagatttgtttgactttgtatgga
gatggtgctgctaatcagggtcagatatttgaaacttacaatatggcagctttgtggaaa
ttgccttgtattttcatttgtgagaataatcgatatggaatgggaacttctgtagagaga
gcagcagccagcactgactattataaaagaggagactatattccaggaataagggtagat
ggaatggatgttttgtgtgtccgtgaggcaacaaaatttgcagctgcctactgcagatca
ggaaagggccccatggtgatggaactacagacatatcgttatcatggacacagcatgagt
gaccctggtgtcagttatcgtactcgggaagaaattcaggaagtgaggagtaagagtgac
cctatcatgcttctcaaggataggatggtgaacaacaaccttgccagtattgaagaatta
aaggaaattgatgtggaagtaaggaaagaaattgaagatgccgcccagtttgctacggct
gatccagaaccacctttggaagaattaggctatcatatctactccagagagccacctttt
gaagttcgtggtgcaaatcaatggatcaagtacaaatctatcagctaa
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