KEGG   Monodelphis domestica (gray short-tailed opossum): 100029049
Entry
100029049         CDS       T01031                                 
Symbol
MAP2K6
Name
(RefSeq) mitogen-activated protein kinase kinase 6
  KO
K04433  mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
Organism
mdo  Monodelphis domestica (gray short-tailed opossum)
Pathway
mdo04010  MAPK signaling pathway
mdo04015  Rap1 signaling pathway
mdo04218  Cellular senescence
mdo04380  Osteoclast differentiation
mdo04620  Toll-like receptor signaling pathway
mdo04664  Fc epsilon RI signaling pathway
mdo04668  TNF signaling pathway
mdo04750  Inflammatory mediator regulation of TRP channels
mdo04912  GnRH signaling pathway
mdo04935  Growth hormone synthesis, secretion and action
mdo04936  Alcoholic liver disease
mdo05014  Amyotrophic lateral sclerosis
mdo05022  Pathways of neurodegeneration - multiple diseases
mdo05132  Salmonella infection
mdo05135  Yersinia infection
mdo05145  Toxoplasmosis
mdo05161  Hepatitis B
mdo05163  Human cytomegalovirus infection
mdo05167  Kaposi sarcoma-associated herpesvirus infection
mdo05169  Epstein-Barr virus infection
mdo05170  Human immunodeficiency virus 1 infection
mdo05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
mdo05417  Lipid and atherosclerosis
mdo05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mdo00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100029049 (MAP2K6)
   04015 Rap1 signaling pathway
    100029049 (MAP2K6)
   04668 TNF signaling pathway
    100029049 (MAP2K6)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    100029049 (MAP2K6)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    100029049 (MAP2K6)
   04664 Fc epsilon RI signaling pathway
    100029049 (MAP2K6)
  09152 Endocrine system
   04912 GnRH signaling pathway
    100029049 (MAP2K6)
   04935 Growth hormone synthesis, secretion and action
    100029049 (MAP2K6)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100029049 (MAP2K6)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    100029049 (MAP2K6)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    100029049 (MAP2K6)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    100029049 (MAP2K6)
   05161 Hepatitis B
    100029049 (MAP2K6)
   05163 Human cytomegalovirus infection
    100029049 (MAP2K6)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100029049 (MAP2K6)
   05169 Epstein-Barr virus infection
    100029049 (MAP2K6)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    100029049 (MAP2K6)
   05135 Yersinia infection
    100029049 (MAP2K6)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    100029049 (MAP2K6)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    100029049 (MAP2K6)
   05022 Pathways of neurodegeneration - multiple diseases
    100029049 (MAP2K6)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100029049 (MAP2K6)
   05418 Fluid shear stress and atherosclerosis
    100029049 (MAP2K6)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    100029049 (MAP2K6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mdo01001]
    100029049 (MAP2K6)
Enzymes [BR:mdo01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     100029049 (MAP2K6)
Protein kinases [BR:mdo01001]
 Serine/threonine kinases: STE group
  STE7 family
   100029049 (MAP2K6)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Seadorna_VP7 Pkinase_fungal Haspin_kinase Choline_kinase DUF4344 CLP1_P APH
Other DBs
NCBI-GeneID: 100029049
NCBI-ProteinID: XP_007482783
Ensembl: ENSMODG00000006330
LinkDB
Position
2:complement(223541574..223626879)
AA seq 335 aa
MIVAENCRKRNPGLKIPKEAFEQPQTSSAPPRDLDSKACISIGDKNFEVKADDLEPIAEL
GRGAYGVVEKMRHMPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVTFYGAL
FREGDVWICMELMDTSLDKFYKQVIDKGLTIPEDILGKIAVSIVKALEHLHSKLSVIHRD
VKPSNVLINTLGQVKMCDFGISGYLVDSVAKTMDAGCKPYMAPERINPELNQKGYNVKSD
IWSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSAEFVDFTSQCLKKNS
KERPTYAELMQHQFFTLHESKATDAASFVKLILGD
NT seq 1008 nt   +upstreamnt  +downstreamnt
atgatagtggcagagaactgcaggaagcggaaccctgggttgaagattccaaaggaagca
tttgaacaacctcagaccagctcagcacctcctcgggatttagattccaaggcttgcatc
tcaattggagataagaattttgaagtgaaggctgatgacttggagcctatagcagaactg
ggacgaggtgcatatggggtggtggagaagatgcgacacatgcctagtgggcagatcatg
gcagtgaagcgaatccgagcaactgtgaatagccaggaacagaagaggctactgatggac
ctggatatctccatgaggacagtggattgccctttcacagtcaccttttatggtgcactc
tttcgggagggtgatgtgtggatctgtatggaactcatggatacctcactggataagttc
tacaaacaagtcattgataagggtttaacaatcccagaggacatcttagggaaaattgca
gtttctattgtaaaagccctagaacatttacacagtaaactttctgtcattcatcgagat
gtgaagccatctaatgtattgatcaatacactgggtcaagtgaagatgtgtgattttggt
attagtggttacctggtggactctgtggccaaaactatggatgcaggatgtaaaccctac
atggctcctgaaagaataaatccagaactaaatcagaaggggtacaatgtgaaatctgac
atttggagcctgggcatcacaatgattgaactggcaatccttaggttcccctatgattcc
tgggggacaccatttcagcagctcaagcaggtggtggaagaaccatcacctcaacttcca
gcagacaagttctcagcagagtttgtcgactttacctcacagtgcttgaagaagaattcc
aaagaacggccaacatatgcagaacttatgcaacatcagtttttcactctgcatgaatcc
aaagcaacagatgcagcatcttttgtaaaactgattcttggagactaa

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