Mycobacterium florentinum: MFLOJ_00500
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Entry
MFLOJ_00500 CDS
T06524
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase E1 component
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
mfj
Mycobacterium florentinum
Pathway
mfj00010
Glycolysis / Gluconeogenesis
mfj00020
Citrate cycle (TCA cycle)
mfj00620
Pyruvate metabolism
mfj00785
Lipoic acid metabolism
mfj01100
Metabolic pathways
mfj01110
Biosynthesis of secondary metabolites
mfj01120
Microbial metabolism in diverse environments
mfj01200
Carbon metabolism
mfj01210
2-Oxocarboxylic acid metabolism
Module
mfj_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
mfj00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
MFLOJ_00500 (aceE)
00020 Citrate cycle (TCA cycle)
MFLOJ_00500 (aceE)
00620 Pyruvate metabolism
MFLOJ_00500 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
MFLOJ_00500 (aceE)
Enzymes [BR:
mfj01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
MFLOJ_00500 (aceE)
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
BBX76263
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Position
complement(45854..48643)
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AA seq
929 aa
AA seq
DB search
MTTEFARHDLAKTPSNGSEPDRVRVIRDGVASYLPDIDPEETSEWLESFDALLERSGPAR
ARYLMLRLLERAGEQRVAIPALTSTDYVNTIPTELEPWFPGDEDVERRFRAWIRWNAAIM
VHRAQRPGIGVGGHISTYASSAALYEVGFNHFFRGKQHPGGGDQIFIQGHASPGIYARAF
LEGRLTADRLDGFRQEHSHPGGGLPSYPHPRLMPDFWEFPTVSMGLGPMNAIYQARFNHY
LHDRGIKDTSDQHVWAFLGDGEMDEPESRGLIQVAANEALDNLTFVINCNLQRLDGPVRG
NGKIIQELESFFRGAGWNVIKVVWGREWDALLHADRDGALVNLMNTTPDGDYQTYKANDG
AYVRDHFFGRDPRTKALVEAMTDSEIWNLKRGGHDYRKVYAAYRAAVDHKGQPTVILAKT
IKGYSLGAHFQGRNATHQMKKLAIEDLKYFRDAIRIPISDAQLEEDPYLPPYYHPGPDAP
EIRYMLDRRRQLGGFLPERPTKAKVLKLPSRDIYAPLKKGSGHQEVATTMALVRTFKEVM
RDKEIGPRIVPIIPDEARTFGMDSWFPSLKIYNRLGQLYTAVDAELMLAYKESEIGQILH
EGINEAGSTASFTAAGTSYATHNEPMIPLYIFYSMFGFQRTGDGLWAAADQMARGFVLGA
TAGRTTLTGEGLQHADGHSLLLAATNPAVVSYDPAFAYEIAYIVESGLARMFGQNPENIY
FYITIYNEPYVQPPQPHNLDPEGVLRGIYRYQAAPERRTNTAQILASGVAMPSAVKAAEM
LAAEWDVAADVWSVTSWGELNRDGLAIQRAQLRHPGEQAGVPYITKALEGTTGPVIAVSD
WMRGVPEQIRPWVPGTYVTLGTDGFGFSDTRPAARRFFNTDAESQVVAVLEALARDGEID
PSVPVAAARQYKIDDVQAAPKQTSDPGVA
NT seq
2790 nt
NT seq
+upstream
nt +downstream
nt
ttgacgaccgagttcgcgcgccacgatttggccaaaaccccaagcaacggaagcgaaccc
gatcgcgtccgggtgatccgagacggtgtcgcgtcgtatctgcccgacatcgatcccgag
gaaacgtcggagtggctcgagtccttcgacgcgctgctggagcgctcgggtccggcgcgg
gcgcgctacctgatgttgcggttgctggaacgagcgggtgaacagcgggttgccatcccg
gcgctcacgtcgaccgactacgtcaacaccatcccgaccgagctggagccgtggttcccc
ggcgacgaggacgtcgaacgtcgcttccgggcctggatccggtggaacgccgcgatcatg
gtgcaccgcgctcagcgtccgggaatcggcgtgggcggccacatttcgacgtacgcctcg
tcggcggcgctgtacgaggtcggcttcaaccacttctttcgcggcaagcagcatcccggc
ggcggggatcagatcttcattcagggccacgcgtccccggggatctacgcgcgcgcgttc
ctggaaggccggctgaccgcggaccggctcgatggcttccgccaggagcacagccatccg
ggcggcgggctgccgtcctacccgcacccgcggctgatgcccgacttctgggagttcccg
acggtgtcgatgggccttggcccgatgaacgccatctaccaggcccgcttcaaccactac
ctgcacgaccgtggcatcaaggacacctcggaccagcacgtctgggcattcctgggcgac
ggcgagatggacgagccggaaagccgcggcctgatccaggtggcggcgaacgaggcactg
gacaacctgaccttcgtcatcaactgcaacctgcagcgcctcgacggcccggtgcgcggc
aacggcaagatcatccaggagctggagtcgttcttccgcggcgccggctggaacgtcatc
aaggtggtctggggccgcgagtgggacgccctgctgcacgccgaccgcgacggcgccctg
gtgaatctgatgaacaccacgcccgacggcgactaccagacctacaaggccaacgacggc
gcctacgtccgcgaccacttcttcggccgcgacccgcgcaccaaggcgctcgtcgaggcg
atgaccgattcggagatctggaacctcaagcgcggcggccacgactaccgcaaggtctac
gccgcctaccgggccgccgtcgaccacaagggacagccgacggtgatcctggccaagacg
atcaagggctactcgctgggcgcgcacttccagggccgcaacgccacgcatcagatgaaa
aagcttgcgatagaagaccttaagtacttccgcgacgccatccggattccgatcagcgac
gcccagctggaggaagacccctacctgccgccgtactaccaccccgggcccgacgccccc
gagatccgctacatgctggaccggcgccgccagctgggcggcttcctgcccgagcgcccg
acgaaggccaaggtgctcaagctgccgagccgcgacatctacgccccgctgaagaagggg
tccgggcaccaagaggtcgccaccacgatggcgctggtgcgcaccttcaaagaagtgatg
cgggacaaggagattggcccgcgcatcgtgccgatcattcccgacgaggcccgcacgttc
ggcatggactcgtggttcccgtcgctgaagatctacaaccgcctcggccagctctacacc
gccgtcgacgccgaattgatgttggcgtacaaggaaagtgaaatcggccagatcctgcac
gagggcatcaacgaggccggctcgacggcgtcgttcaccgcggccggtacgtcgtacgcg
acgcacaacgagccgatgatcccgctctacatcttctattcgatgttcggattccagcgc
accggcgacggcctgtgggccgcggccgaccagatggcccgcggctttgtgctgggggcc
accgcggggcgcaccaccctgaccggtgagggcttgcagcatgccgacggtcactcgctg
ctgctggccgccaccaacccggcggtggtctcctacgacccggcgttcgcctacgagatc
gcctacatcgtcgagagcgggctggcccggatgttcggccagaacccggagaacatctac
ttctacatcaccatctacaacgagccgtatgtgcagccgccgcagccgcacaacctggat
cccgagggcgtgctgcgcgggatctaccgctatcaggcggcccccgagcgacgcaccaac
accgcgcagatcctggcctccggcgtcgcgatgccgtcggcggtgaaggccgccgagatg
ctggccgccgagtgggatgtcgccgccgacgtgtggtcggtgaccagctggggtgagctc
aaccgcgacgggctggcgattcagcgggctcagctgcggcaccccggcgagcaggccggc
gtcccgtacatcacgaaggcgctggaagggaccaccgggccggtgatcgccgtatcggac
tggatgcgcggagtgcccgagcagatccggccgtgggtgcccggcacctacgtcacgctg
ggcaccgacgggttcgggttctccgacacccgcccggcggcgcggcggttcttcaacacc
gacgcggagtcgcaggtcgtggcggtgcttgaggcgctggcccgcgacggcgagatcgac
ccgtcggtgccggtcgcggcggcccgtcagtacaagatcgacgacgtgcaggccgctccc
aagcagacgtccgaccccggcgtggcctag
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