Microtus fortis (reed vole): 126488334
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Entry
126488334 CDS
T08493
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial isoform X1
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
mfot
Microtus fortis (reed vole)
Pathway
mfot00010
Glycolysis / Gluconeogenesis
mfot00020
Citrate cycle (TCA cycle)
mfot00620
Pyruvate metabolism
mfot00785
Lipoic acid metabolism
mfot01100
Metabolic pathways
mfot01200
Carbon metabolism
mfot01210
2-Oxocarboxylic acid metabolism
mfot04066
HIF-1 signaling pathway
mfot04922
Glucagon signaling pathway
mfot05230
Central carbon metabolism in cancer
mfot05415
Diabetic cardiomyopathy
Module
mfot_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
mfot00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
126488334
00020 Citrate cycle (TCA cycle)
126488334
00620 Pyruvate metabolism
126488334
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
126488334
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
126488334
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
126488334
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
126488334
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
126488334
Enzymes [BR:
mfot01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
126488334
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Ortholog
Paralog
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Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
126488334
NCBI-ProteinID:
XP_049977706
LinkDB
All DBs
Position
Unknown
AA seq
391 aa
AA seq
DB search
MRKMLAAVVSHVFSGATQKPAMRGLLASLNFSNDATCDIKKCDLYRLEEGPPTSTVLTRE
EALKYYRTMQVIRRMELKSDQMYKQKFIRGFCHLCDGQEACCVGLEAGINPTDHVITSYR
AHGLCYTRGLSVKSILAELTGRRGGCAKGKGGSMHMYGKHFYGGNGIVGAQVPLGAGVAF
ACKYLGNGQVCLALYGDGAANQGQVAEAYNISALWKLPCVFICENNRYGMGTAVERAAAS
TDYHKRGNFIPGLRVNGMDILSVREATKFAADHCRSGKGPILMELQTYRYHGHSMSDPGV
SYRSREEVHNMRSKSDPIMLLRERMINNNLSNVEELKEIDADVRKEVEEAAQFAITDPEP
TLDELAHHLYYRNSPFEVRGTNKWIKYMSVS
NT seq
1176 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagatgctggccgctgtggtgtcccacgtgttttcgggagcgacccagaagccg
gccatgagagggctgctggcgtccctgaacttctccaacgacgccacctgcgacattaag
aaatgcgacctgtaccggctggaagagggccctccgacctccaccgtgctcacccgagag
gaggccctcaagtactaccggaccatgcaggtgattcggcgcatggagctgaagtctgac
cagatgtacaagcagaagttcattcgtggtttctgtcacctgtgtgatgggcaagaagcc
tgctgcgtggggctggaggcagggatcaatcccacggatcacgtcatcacgtcctaccgg
gctcatggcttgtgctacacacgggggctgtcggtcaaatccattctcgccgagctgact
ggacgccgaggaggctgtgccaagggcaaaggaggctcgatgcacatgtacggcaagcac
ttctacggaggcaatggcattgttggggcacaggtaccactgggagccggtgtcgctttc
gcctgtaaatacctgggaaatggtcaggtctgcctggctctgtatggcgacggtgcggct
aaccaggggcaggtggccgaagcttacaatatatcggccttgtggaaattaccttgtgtc
ttcatctgtgagaataaccgctacggaatggggacagccgttgagagagcagcagccagc
actgattaccacaagagaggcaattttatccctggactgagggtgaatgggatggatatc
ctctctgtccgtgaggcgaccaagtttgcagctgatcactgcagatctggaaaggggccc
attttgatggaactgcagacctaccgttatcatggacacagtatgagtgacccaggggtc
agttaccgttcacgagaagaagttcacaacatgcgaagcaagagtgatcctattatgctt
ctccgagagagaatgataaacaacaacctcagcaacgttgaagagttgaaggaaatcgat
gcagatgtgagaaaagaagttgaggaagcagcccagtttgctataactgatccagaacca
actttggacgaattagctcatcacctctactaccgcaattcaccatttgaagttcgtggt
acaaataaatggatcaagtatatgtctgtcagttag
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