KEGG   Microtus fortis (reed vole): 126492719
Entry
126492719         CDS       T08493                                 
Name
(RefSeq) mitogen-activated protein kinase 12 isoform X1
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
mfot  Microtus fortis (reed vole)
Pathway
mfot01522  Endocrine resistance
mfot04010  MAPK signaling pathway
mfot04015  Rap1 signaling pathway
mfot04068  FoxO signaling pathway
mfot04071  Sphingolipid signaling pathway
mfot04114  Oocyte meiosis
mfot04148  Efferocytosis
mfot04218  Cellular senescence
mfot04261  Adrenergic signaling in cardiomyocytes
mfot04370  VEGF signaling pathway
mfot04380  Osteoclast differentiation
mfot04550  Signaling pathways regulating pluripotency of stem cells
mfot04611  Platelet activation
mfot04613  Neutrophil extracellular trap formation
mfot04620  Toll-like receptor signaling pathway
mfot04621  NOD-like receptor signaling pathway
mfot04622  RIG-I-like receptor signaling pathway
mfot04625  C-type lectin receptor signaling pathway
mfot04657  IL-17 signaling pathway
mfot04658  Th1 and Th2 cell differentiation
mfot04659  Th17 cell differentiation
mfot04660  T cell receptor signaling pathway
mfot04664  Fc epsilon RI signaling pathway
mfot04668  TNF signaling pathway
mfot04670  Leukocyte transendothelial migration
mfot04714  Thermogenesis
mfot04722  Neurotrophin signaling pathway
mfot04723  Retrograde endocannabinoid signaling
mfot04728  Dopaminergic synapse
mfot04750  Inflammatory mediator regulation of TRP channels
mfot04912  GnRH signaling pathway
mfot04914  Progesterone-mediated oocyte maturation
mfot04917  Prolactin signaling pathway
mfot04926  Relaxin signaling pathway
mfot04932  Non-alcoholic fatty liver disease
mfot04933  AGE-RAGE signaling pathway in diabetic complications
mfot04935  Growth hormone synthesis, secretion and action
mfot04936  Alcoholic liver disease
mfot05014  Amyotrophic lateral sclerosis
mfot05020  Prion disease
mfot05022  Pathways of neurodegeneration - multiple diseases
mfot05132  Salmonella infection
mfot05133  Pertussis
mfot05135  Yersinia infection
mfot05140  Leishmaniasis
mfot05142  Chagas disease
mfot05145  Toxoplasmosis
mfot05152  Tuberculosis
mfot05161  Hepatitis B
mfot05163  Human cytomegalovirus infection
mfot05167  Kaposi sarcoma-associated herpesvirus infection
mfot05169  Epstein-Barr virus infection
mfot05170  Human immunodeficiency virus 1 infection
mfot05171  Coronavirus disease - COVID-19
mfot05205  Proteoglycans in cancer
mfot05208  Chemical carcinogenesis - reactive oxygen species
mfot05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
mfot05415  Diabetic cardiomyopathy
mfot05417  Lipid and atherosclerosis
mfot05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mfot00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    126492719
   04015 Rap1 signaling pathway
    126492719
   04370 VEGF signaling pathway
    126492719
   04668 TNF signaling pathway
    126492719
   04068 FoxO signaling pathway
    126492719
   04071 Sphingolipid signaling pathway
    126492719
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    126492719
  09143 Cell growth and death
   04114 Oocyte meiosis
    126492719
   04218 Cellular senescence
    126492719
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    126492719
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    126492719
   04613 Neutrophil extracellular trap formation
    126492719
   04620 Toll-like receptor signaling pathway
    126492719
   04621 NOD-like receptor signaling pathway
    126492719
   04622 RIG-I-like receptor signaling pathway
    126492719
   04625 C-type lectin receptor signaling pathway
    126492719
   04660 T cell receptor signaling pathway
    126492719
   04658 Th1 and Th2 cell differentiation
    126492719
   04659 Th17 cell differentiation
    126492719
   04657 IL-17 signaling pathway
    126492719
   04664 Fc epsilon RI signaling pathway
    126492719
   04670 Leukocyte transendothelial migration
    126492719
  09152 Endocrine system
   04912 GnRH signaling pathway
    126492719
   04914 Progesterone-mediated oocyte maturation
    126492719
   04917 Prolactin signaling pathway
    126492719
   04926 Relaxin signaling pathway
    126492719
   04935 Growth hormone synthesis, secretion and action
    126492719
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    126492719
  09156 Nervous system
   04728 Dopaminergic synapse
    126492719
   04723 Retrograde endocannabinoid signaling
    126492719
   04722 Neurotrophin signaling pathway
    126492719
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    126492719
  09158 Development and regeneration
   04380 Osteoclast differentiation
    126492719
  09159 Environmental adaptation
   04714 Thermogenesis
    126492719
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    126492719
   05208 Chemical carcinogenesis - reactive oxygen species
    126492719
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    126492719
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    126492719
   05161 Hepatitis B
    126492719
   05171 Coronavirus disease - COVID-19
    126492719
   05163 Human cytomegalovirus infection
    126492719
   05167 Kaposi sarcoma-associated herpesvirus infection
    126492719
   05169 Epstein-Barr virus infection
    126492719
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    126492719
   05135 Yersinia infection
    126492719
   05133 Pertussis
    126492719
   05152 Tuberculosis
    126492719
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    126492719
   05140 Leishmaniasis
    126492719
   05142 Chagas disease
    126492719
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    126492719
   05020 Prion disease
    126492719
   05022 Pathways of neurodegeneration - multiple diseases
    126492719
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    126492719
   05418 Fluid shear stress and atherosclerosis
    126492719
   05415 Diabetic cardiomyopathy
    126492719
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    126492719
   04932 Non-alcoholic fatty liver disease
    126492719
   04933 AGE-RAGE signaling pathway in diabetic complications
    126492719
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    126492719
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mfot01001]
    126492719
Enzymes [BR:mfot01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     126492719
Protein kinases [BR:mfot01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   126492719
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 APH Kdo Haspin_kinase UvrD_C Kinase-like
Other DBs
NCBI-GeneID: 126492719
NCBI-ProteinID: XP_049985238
LinkDB
Position
Unknown
AA seq 376 aa
MGLGMQPEMSGRQNQIPPPKRRRMNQPQGRGILGKEELSQEQENNWVGCDCSAIDSRTGN
KVAIKKLYRPFQSELFAKRAYRELRLLKHMRHENVIGLLDVFTPDETLDDFTDFYLVMPF
MGTDLGKLMKHETLSEDRIQFLVYQMLKGLKYIHAAGVIHRDLKPGNLAVNEDCELKILD
FGLARQADSEMTGYVVTRWYRAPEVILNWMRYTQTVDIWSVGCIMAEMITGKILFKGSDH
LDQLKEIMKVTGTPPPEFVQKLQSAEAKNYMEGLPELEKKDFASVLTNASPQAVNLLEKM
LVLDSEQRVTAAEALAHPYFESLQDTEDESKAQKYDDSFDDVDRTLEEWKRVTYKEVLSF
KPPRQLGARVPKETAL
NT seq 1131 nt   +upstreamnt  +downstreamnt
atggggttgggaatgcaacctgagatgtctgggagacagaaccaaatacctcctccaaag
agaagaagaatgaatcagccccaggggcggggcatccttgggaaagaagagttaagccag
gaacaggaaaacaattgggttgggtgtgattgctctgcaatagacagccgcactggtaac
aaggtggccatcaagaagttgtaccggcccttccagtcggagctgtttgccaagcgcgcc
tacagagagctgcgcctcctcaaacacatgcgccacgagaacgtgattggcctactggat
gtgttcactcctgatgagactctggatgacttcacagacttctacctggtgatgccgttc
atgggcactgatctgggcaagctgatgaagcatgagactctgagtgaagacagaatccag
tttcttgtgtatcagatgctgaaggggctgaagtatatccacgctgctggtgtcatccac
agggatttgaagcctggcaacctggctgtgaatgaagactgtgagctgaagatcctagac
tttggcctagccagacaggcagacagtgagatgacgggatatgtggtgacccggtggtac
cgggcaccagaggtcatcttgaattggatgcgctacactcagacagtggacatttggtct
gtcggctgcatcatggcggagatgattacagggaagattctgttcaaaggcagtgaccac
ctggaccagctgaaggagatcatgaaggtcacagggacaccccctcctgagtttgtacag
aagttacagagtgctgaggccaagaactacatggaaggccttcctgagctggaaaaaaag
gattttgcctctgtcctgaccaacgcaagccctcaggctgtgaaccttctagaaaagatg
ctggtgctggactcagaacagcgggtgacggcagctgaggcactggcccatccgtacttt
gagtccctgcaggataccgaggatgagtccaaggcccagaaatatgatgactcctttgat
gacgtagaccgcacccttgaggagtggaagcgtgttacttacaaggaagtgctcagcttc
aagcctcccaggcagctaggagccagagtcccaaaggagacagctctatga

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