Mycolicibacterium gadium: MGAD_22510
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Entry
MGAD_22510 CDS
T07053
Symbol
pdhA
Name
(GenBank) pyruvate dehydrogenase E1 component subunit alpha
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
mgad
Mycolicibacterium gadium
Pathway
mgad00010
Glycolysis / Gluconeogenesis
mgad00020
Citrate cycle (TCA cycle)
mgad00620
Pyruvate metabolism
mgad00785
Lipoic acid metabolism
mgad01100
Metabolic pathways
mgad01110
Biosynthesis of secondary metabolites
mgad01120
Microbial metabolism in diverse environments
mgad01200
Carbon metabolism
mgad01210
2-Oxocarboxylic acid metabolism
Module
mgad_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
mgad00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
MGAD_22510 (pdhA)
00020 Citrate cycle (TCA cycle)
MGAD_22510 (pdhA)
00620 Pyruvate metabolism
MGAD_22510 (pdhA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
MGAD_22510 (pdhA)
Enzymes [BR:
mgad01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
MGAD_22510 (pdhA)
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Gene cluster
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Motif
Pfam:
E1_dh
TPP_enzyme_C
Motif
Other DBs
NCBI-ProteinID:
BBZ17916
UniProt:
A0A7I7WJU8
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All DBs
Position
2238306..2239286
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AA seq
326 aa
AA seq
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MIDHDTATTLLSDMVRVRLMEEKCAELYSAAKIRGFLHLYVGEEAVAAGSLRMLEAEDAV
VATYRDHAHALLRGVPMTRIMAEMFGKQEGCSRGRGGSMHLFDARTRFYGGNAIVGSGLP
LAVGLALADKQLGKPRVTACYFGEGAVAEGAFHESLNLAELWQLPVLFCCENNFYAMGTA
LAVEQSQTDMTAKASSYRIPALAVDGMDVLACHTAAQEGVYHVRNGGGPFFLEFRTYRFR
PHSMFDPELYRGKSEVEHWKERDPIRTFTERCLADGALTDDDIAAIRRAAEEELDEAVAY
AEAGTWEPVEDLSRDVMTPATAEALR
NT seq
981 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgaccacgacaccgcgacgacgctgctgtcggacatggtgcgggtgcgcctgatg
gaagagaagtgcgctgagctctacagcgcggccaagatccgcggattcctgcacctttac
gtcggtgaggaggcggtggccgccgggtcgctgcggatgctggaagccgaggacgctgtg
gtggccacctaccgcgatcacgcgcacgccctgcttcggggtgtcccgatgaccagaatc
atggccgagatgttcggcaagcaggagggttgctcccgtgggcgcggcggctcgatgcac
ctgttcgacgcgcgcacccgcttctacggcggcaacgccatcgtcggcagcggcctcccg
ctggcggtaggtctcgcgctggccgacaagcagctgggcaagccacgggttaccgcctgc
tacttcggcgaaggtgcggtcgccgaaggcgcctttcacgaatcgctgaacctagccgaa
ctctggcagttgccggtgctgttctgctgcgagaacaacttctatgcgatggggacggcc
ctcgcggtggagcagtcgcagacggacatgaccgcgaaggcgtcgtcgtaccggataccg
gcgctggcggtcgacggcatggatgtgctggcatgccataccgccgcccaagagggcgtg
taccacgtccgcaatggtggcggtccgttcttcctggagttccgcacctatcggttccgt
ccgcattcgatgttcgatcccgagttgtaccggggcaaaagcgaagtcgaacactggaag
gagcgtgacccgatccgcaccttcaccgagcggtgcctggccgacggcgcgctcaccgac
gacgacatcgccgcgatccgccgcgccgccgaagaggaactggacgaggcggtggcctac
gccgaggccggcacctgggagcccgtggaggatctcagccgtgacgtgatgacacctgcg
acggcggaggcgctccgatga
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