Meleagris gallopavo (turkey): 100543712
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Entry
100543712 CDS
T01523
Symbol
GCLC
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
mgp
Meleagris gallopavo (turkey)
Pathway
mgp00270
Cysteine and methionine metabolism
mgp00480
Glutathione metabolism
mgp01100
Metabolic pathways
mgp01240
Biosynthesis of cofactors
mgp04216
Ferroptosis
Module
mgp_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
mgp00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
100543712 (GCLC)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
100543712 (GCLC)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
100543712 (GCLC)
Enzymes [BR:
mgp01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
100543712 (GCLC)
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Gene cluster
GFIT
Motif
Pfam:
GCS
GCS2
SANT_DAMP1_like
DUF2811
Motif
Other DBs
NCBI-GeneID:
100543712
NCBI-ProteinID:
XP_031408451
Ensembl:
ENSMGAG00000013920
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Position
2:87089814..87109854
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AA seq
583 aa
AA seq
DB search
MLVKFDHENKKVRLVLSGEEVLQTLQDKGEKINPNHPTLWRPEYGSYMIEGTPGQPYGGT
MSEFNTVQDNMRKRRQEAASVLKENEAICTVTSFPRLGCPGFTLPEYKPTPVEGGASKSL
FFPDEAINKHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPSPFIETFPNDDGEAAKAAK
PDFIYMDAMGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYVSD
IDCRWGVISASVDDRTREERGLEPLKNNHYRISKSRYDSIDSYLSECGEKYNDIDLTIDK
DIYEHLIKEGIDHLLAQHIAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFK
PPPPNSDIGWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKM
AQKRDAVRQGMFYFRKDICKGGNVVVDGCGSAQNGTGTDTEEYTLMSIDTIINGKEGVFP
GLIPILNSYLENMEVDVDTRCTILNYLKLIKKRASGELMTVARWMREFISQHPDYKQDSV
ITDEMNYSLIWKCNQIALGQAECPELLGVGFNKKPSGNKTDPL
NT seq
1752 nt
NT seq
+upstream
nt +downstream
nt
atgttagtaaaatttgaccatgagaataagaaagtacgcttagtgctgagtggcgaagaa
gttcttcaaacactgcaagacaagggggagaagataaaccccaaccacccaacactctgg
cgaccagaatatggaagctatatgattgaaggcacacccgggcagccatatgggggaacc
atgtctgaattcaacactgttcaagacaacatgaggaaaaggaggcaagaggccgcttct
gtgctgaaagaaaacgaggctatttgcactgtgacatcttttccaaggttagggtgtcct
gggtttacgctgccggaatacaagccaactccagtagaaggaggagcttcaaaatccctc
ttctttccagatgaagccatcaataaacatcctagatttagtacactgaccagaaacatt
cggcaccgaagaggagagaaggttgtcataaatgtaccaatctttaaagataagaacaca
ccatcaccgttcatagaaacatttcctaatgatgatggagaagcagcaaaagcagcaaaa
ccagactttatatatatggacgctatggggtttggaatgggcaactgctgtcttcaggta
acattccaggcttgcagcatttctgaagcaagatatctctatgatcaactagccacaatc
tgtcccattgtgatggccttgagtgctgcatctccgttctacagaggctatgtgtctgat
attgattgtcgctggggagtaatatctgcatctgtggatgatcgaacgcgagaagagagg
gggctggagccactgaagaacaaccattatagaatcagtaaatccagatatgattccata
gacagttatctatctgaatgtggtgagaaatacaatgacattgatttgacaatagacaaa
gatatctacgagcacctaataaaggaaggtattgaccaccttttggcacagcatattgca
cacttgtttattcgagacccattgactttgtttgaggagaaaatacatctagatgatgca
aatgaatccgaccattttgagaacattcagtctacaaactggcagacaatgagattcaaa
ccaccccctccaaattcagatataggatggagagtggaattcaggcctatggaggtccag
ttaacagactttgaaaactctgcatacgttgtgtttgtggtgctgctaactcgagtcatt
ctgtcatacaaactggattttctcattcctttgtccaaggtggatgaaaatatgaagatg
gcccagaaaagagatgctgttcggcaaggaatgttttacttcagaaaggatatttgcaaa
ggtggaaatgtcgttgtggatggatgtggctctgcacaaaatgggacgggcacagacaca
gaagagtacaccttaatgagcatcgatacaattataaacgggaaggaaggagtctttcct
ggtttgatcccaattttgaattcttaccttgaaaacatggaggtggatgtggacacaaga
tgcaccatcctaaactacttgaagttaataaaaaagagagcatctggagaattaatgaca
gttgctcgatggatgagggaattcatctcacagcacccagactacaagcaggatagtgtg
ataacagatgaaatgaattacagccttatttggaaatgcaaccaaatcgcactaggccag
gcagaatgtccagaactgttgggggtaggatttaacaagaagccaagtggaaacaaaact
gaccctttgtaa
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