Mannheimia haemolytica USDA-ARS-USMARC-185: D648_13340
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Entry
D648_13340 CDS
T02522
Name
(GenBank) bifunctional tetrahydrofolate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
mht
Mannheimia haemolytica USDA-ARS-USMARC-185
Pathway
mht00790
Folate biosynthesis
mht01100
Metabolic pathways
mht01240
Biosynthesis of cofactors
Module
mht_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
mht00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
D648_13340
Enzymes [BR:
mht01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
D648_13340
6.3.2.17 tetrahydrofolate synthase
D648_13340
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
AGI35338
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Position
1216934..1218235
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AA seq
433 aa
AA seq
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MNTLSIPKATDSLETWLSYLEQAHSKPIDMGLDRIRKVATELDLLKPAPYVITVAGTNGK
GSTCRLLEVTLLKAGFRVGVYSSPHLIHYNERVRINGEVLPDADHVQAFAKINAKKTASL
TYFEFSTLSAFELFKQNQLDIVILEVGLGGRLDATNIIDPSLAVIISIDIDHVAFLGDNR
EDIGREKAGIFRENIPVVIGEPDCPHSIKQIADSLNCHAFYRGKDWQFEIKNNLFHWYSE
EKSFTDLPIPLIPIPNAGTALAVLMQLPFEIDEKIIRQALNEAQMTGRFQTLTDTDFTHF
SQPKPAAKVIIDVGHNPHAARYLADKLRELKQPNQKIYAVFSALEDKDLSGIVEPLANII
DEWHCAGLDCWRGQTGEAVLAKLVNVLPNSTACSYENVAQASRVLFETANENDIVLVFGS
FHTVADFMLWLET
NT seq
1302 nt
NT seq
+upstream
nt +downstream
nt
atgaatacattaagcatacctaaagccacggattctttggaaacgtggctttcctattta
gaacaagcccattctaaaccgattgatatgggcttagatcgtattcgtaaggtcgcaaca
gagctggatttactcaagcctgccccttatgtgattaccgttgccggtactaacggcaag
ggttcgacctgccgtttgttagaagttaccttattaaaagccggatttcgggttggtgtt
tactcttcaccgcacttaattcactataatgaacgggtgcgaattaacggcgaagtatta
cctgatgccgaccacgtccaagcatttgcaaaaattaatgcaaaaaagaccgcttcactc
acttattttgagtttagtacgctgtctgcatttgagctattcaaacaaaatcagctcgat
attgtgattttagaagtcggattaggtgggcgattagatgccactaatattattgatcca
agccttgccgtgattatctcgattgatatcgaccacgttgcatttttaggcgataaccgt
gaagacatcgggcgtgagaaagccggcattttccgtgaaaatattccggttgtcatcggc
gagcctgattgccctcattcgattaaacagattgctgattcgttaaattgtcacgctttt
taccggggtaaagactggcagtttgaaattaagaataatctgtttcattggtattctgaa
gaaaaatcctttaccgatttaccaatcccgcttattccgattccaaacgccggcaccgca
ttagcagtattaatgcaactgccatttgaaattgatgaaaagattattcgacaagcctta
aatgaagctcaaatgacagggcgttttcaaaccctgacggataccgattttactcatttt
tctcaacctaaaccggctgcaaaagtaattattgatgtagggcataacccacacgcagca
cgttatttagctgacaaactgcgggagttaaagcaaccaaatcaaaaaatctatgcggtg
tttagtgcgttagaagataaggatttatccggtattgtcgagccattagctaatattatt
gatgaatggcattgtgcagggctagattgttggcgtggacaaacaggcgaggcggtgtta
gcgaaattggtaaacgttttgccaaattcaaccgcttgtagctatgaaaatgtggcacag
gcaagccgagtattgtttgaaacagccaacgaaaatgatattgtgctggtgttcggctca
tttcatacggtagcagattttatgctttggttggaaacctag
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